SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gs2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 5gs2 ANTI-MBP
ANTI-REPEBODY
(Homo
sapiens;
Mus
musculus) 		6 / 12 TYR D 162
GLN D 215
PHE D 224
VAL H  37
ALA H  97
TRP H 117
 None
 0.67A 1h8sA-5gs2D:
21.4		 1h8sA-5gs2D:
39.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 5gs2 ANTI-MBP
ANTI-REPEBODY
(Homo
sapiens;
Mus
musculus) 		6 / 12 TYR H 168
TYR H 226
PHE H 230
VAL D  37
ALA D  97
TRP D 111
 None
 0.39A 1h8sA-5gs2H:
13.2		 1h8sA-5gs2H:
76.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5gs2 REPEBODY
(Escherichia
coli) 		3 / 3 HIS B 209
ASP B 163
ASN B 166
 None
 0.82A 1wg8B-5gs2B:
undetectable		 1wg8B-5gs2B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5gs2 ANTI-REPEBODY
(Mus
musculus) 		4 / 7 ARG D 192
GLY D 194
SER D 156
SER D 154
 None
 1.04A 2c8aB-5gs2D:
undetectable		 2c8aB-5gs2D:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5gs2 ANTI-REPEBODY
(Mus
musculus) 		4 / 7 ARG D 192
GLY D 194
SER D 156
SER D 154
 None
 1.10A 2c8aD-5gs2D:
undetectable		 2c8aD-5gs2D:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_A_CLUA808_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 5gs2 ANTI-MBP
ANTI-REPEBODY
(Homo
sapiens;
Mus
musculus) 		4 / 7 ALA D 107
TYR D 105
TYR H 181
TYR H 168
 None
 1.19A 2pncA-5gs2D:
undetectable		 2pncA-5gs2D:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 5gs2 REPEBODY
(Escherichia
coli) 		4 / 7 ILE B 231
TYR B 226
PHE B 201
ASP B 202
 None
 1.16A 2qebA-5gs2B:
undetectable		 2qebA-5gs2B:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 5gs2 REPEBODY
(Escherichia
coli) 		4 / 7 ILE B 231
TYR B 226
PHE B 201
ASP B 202
 None
 1.13A 2qebB-5gs2B:
undetectable		 2qebB-5gs2B:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DFR_A_MTXA164_1
(DIHYDROFOLATE
REDUCTASE)		 5gs2 ANTI-MBP
(Homo
sapiens) 		6 / 12 LEU H 236
ASP H 149
PRO H 191
LEU H 179
ALA H 216
THR H 145
 None
 1.34A 3dfrA-5gs2H:
undetectable		 3dfrA-5gs2H:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_A_ACRA720_1
(ALPHA-AMYLASE, SUSG)		 5gs2 REPEBODY
(Escherichia
coli) 		4 / 7 TYR B  61
GLU B  83
LEU B  40
ASN B  41
 None
 1.41A 3k8mA-5gs2B:
undetectable		 3k8mA-5gs2B:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 5gs2 REPEBODY
(Escherichia
coli) 		4 / 7 ASP B  16
GLN B  11
PRO B  14
GLN B  57
 None
 1.21A 3l2vA-5gs2B:
undetectable		 3l2vA-5gs2B:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5gs2 ANTI-MBP
REPEBODY
(Escherichia
coli;
Homo
sapiens) 		4 / 6 GLN H 222
MET H 136
ILE H 134
SER B 123
 None
 1.27A 3pmzD-5gs2H:
undetectable		 3pmzD-5gs2H:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5gs2 ANTI-MBP
REPEBODY
(Escherichia
coli;
Homo
sapiens) 		4 / 6 GLN H 222
MET H 136
ILE H 134
SER B 123
 None
 1.27A 3pmzD-5gs2H:
undetectable		 3pmzD-5gs2H:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 5gs2 REPEBODY
(Escherichia
coli) 		4 / 7 VAL B 196
LEU B 227
PHE B 177
LEU B 207
 None
 1.06A 3qeoB-5gs2B:
undetectable		 3qeoB-5gs2B:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5gs2 REPEBODY
(Escherichia
coli) 		5 / 12 VAL B  35
PHE B  18
ILE B  22
ASN B  25
PHE B  13
 None
 1.44A 4c49D-5gs2B:
undetectable		 4c49D-5gs2B:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5gs2 ANTI-REPEBODY
ANTI-MBP
(Mus
musculus;
Homo
sapiens) 		4 / 7 ARG H  38
PRO D  14
SER D 121
VAL H  64
 None
 1.27A 4kmmA-5gs2H:
undetectable		 4kmmA-5gs2H:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HSW_A_ACTA501_0
(ORF 37)		 5gs2 ANTI-MBP
(Homo
sapiens) 		4 / 5 SER H  52
SER H  53
SER H  54
SER H  32
 None
 0.95A 5hswA-5gs2H:
undetectable		 5hswA-5gs2H:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5gs2 ANTI-MBP
ANTI-REPEBODY
(Homo
sapiens;
Mus
musculus) 		3 / 3 VAL D  37
HIS H 223
VAL D 108
 None
 0.53A 5jmnC-5gs2D:
1.6		 5jmnC-5gs2D:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 5gs2 ANTI-REPEBODY
(Mus
musculus) 		3 / 3 THR D  28
SER D  31
TYR D  32
 None
 0.77A 5jsdA-5gs2D:
2.5		 5jsdA-5gs2D:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 5gs2 ANTI-REPEBODY
(Mus
musculus) 		3 / 3 THR D  28
SER D  31
TYR D  32
 None
 0.78A 5jsdB-5gs2D:
undetectable		 5jsdB-5gs2D:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 5gs2 ANTI-REPEBODY
(Mus
musculus) 		3 / 3 THR D  28
SER D  31
TYR D  32
 None
 0.77A 5jsdC-5gs2D:
undetectable		 5jsdC-5gs2D:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 5gs2 ANTI-REPEBODY
(Mus
musculus) 		3 / 3 THR D  28
SER D  31
TYR D  32
 None
 0.79A 5jseA-5gs2D:
2.6		 5jseA-5gs2D:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 5gs2 ANTI-REPEBODY
(Mus
musculus) 		3 / 3 THR D  28
SER D  31
TYR D  32
 None
 0.78A 5jseB-5gs2D:
undetectable		 5jseB-5gs2D:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 5gs2 ANTI-REPEBODY
(Mus
musculus) 		3 / 3 THR D  28
SER D  31
TYR D  32
 None
 0.78A 5jseC-5gs2D:
2.8		 5jseC-5gs2D:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 5gs2 REPEBODY
(Escherichia
coli) 		5 / 9 LEU B  75
ASN B  73
ILE B  47
VAL B  56
ILE B  53
 None
 1.15A 5kr2D-5gs2B:
undetectable		 5kr2D-5gs2B:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 5gs2 REPEBODY
(Escherichia
coli) 		6 / 12 LEU B 169
ALA B 249
PHE B 201
LEU B 183
LEU B 204
VAL B 200
 None
 1.44A 5tudA-5gs2B:
undetectable		 5tudA-5gs2B:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_1
(NS3 PROTEASE)		 5gs2 ANTI-MBP
(Homo
sapiens) 		5 / 9 ARG H  38
ALA H  88
VAL H 125
SER H 126
ASP H  90
 None
 1.48A 6c2mA-5gs2H:
undetectable		 6c2mA-5gs2H:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5gs2 REPEBODY
ANTI-REPEBODY
(Escherichia
coli;
Mus
musculus) 		3 / 3 GLN B 192
TYR D  54
ASN D  52
 None
 0.78A 6dwdC-5gs2B:
undetectable		 6dwdC-5gs2B:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 5gs2 REPEBODY
(Escherichia
coli) 		5 / 12 ASP B  77
LEU B 132
ASP B 106
LEU B 111
LEU B  92
 None
 1.14A 6ew0F-5gs2B:
undetectable		 6ew0F-5gs2B:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_1
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 5gs2 ANTI-REPEBODY
ANTI-MBP
(Mus
musculus;
Homo
sapiens) 		4 / 4 ASP H 133
SER H 127
SER H 126
ASN D  61
 None
 1.41A 6iblA-5gs2H:
undetectable		 6iblA-5gs2H:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_1
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 5gs2 ANTI-REPEBODY
ANTI-MBP
(Mus
musculus;
Homo
sapiens) 		4 / 4 ASP H 133
SER H 127
SER H 126
ASN D  61
 None
 1.37A 6iblB-5gs2H:
undetectable		 6iblB-5gs2H:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IEY_A_CLMA401_0
(ESTERASE)		 5gs2 REPEBODY
(Escherichia
coli) 		5 / 11 ILE B  59
ALA B  69
LEU B  92
GLY B  71
SER B  51
 None
 1.24A 6ieyA-5gs2B:
undetectable
6ieyB-5gs2B:
undetectable		 6ieyA-5gs2B:
20.00
6ieyB-5gs2B:
20.00