SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gs3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DV1_A_SRYA1601_1 (16S RRNA RIBOSOMAL PROTEIN S12)	5gs3	DIABODY PROTEIN (Homo sapiens)	3 / 3	LYS H 166 LYS H 163 PRO H 164	None	1.21A	4dv1L-5gs3H: undetectable	4dv1L-5gs3H: 19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECM_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	5gs3	DIABODY PROTEIN (Homo sapiens)	4 / 7	ALA H 92 THR H 91 VAL H 115 GLU H 89	None	0.75A	5ecmD-5gs3H: undetectable	5ecmD-5gs3H: 17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECO_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	5gs3	DIABODY PROTEIN (Homo sapiens)	4 / 7	ALA H 92 THR H 91 VAL H 115 GLU H 89	None	0.84A	5ecoD-5gs3H: undetectable	5ecoD-5gs3H: 17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L4E_D_EDPD402_1 (PROTON-GATED ION CHANNEL)	5gs3	DIABODY PROTEIN (Homo sapiens)	4 / 8	THR H 198 SER H 187 THR H 196 SER H 189	None	0.96A	5l4eA-5gs3H: undetectable 5l4eB-5gs3H: undetectable 5l4eC-5gs3H: undetectable 5l4eD-5gs3H: undetectable 5l4eE-5gs3H: undetectable	5l4eA-5gs3H: 20.06 5l4eB-5gs3H: 20.06 5l4eC-5gs3H: 20.06 5l4eD-5gs3H: 20.06 5l4eE-5gs3H: 20.06

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4DV1_A_SRYA1601_1","16S RRNA;RIBOSOMAL PROTEIN S12","5gs3","DIABODY PROTEIN","Homo sapiens",3,"LYS H 166;LYS H 163;PRO H 164","None","1.21A","4dv1L-5gs3H:undetectable","4dv1L-5gs3H:19.67"],["5ECM_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","5gs3","DIABODY PROTEIN","Homo sapiens",4,"ALA H  92;THR H  91;VAL H 115;GLU H  89","None","0.75A","5ecmD-5gs3H:undetectable","5ecmD-5gs3H:17.63"],["5ECO_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","5gs3","DIABODY PROTEIN","Homo sapiens",4,"ALA H  92;THR H  91;VAL H 115;GLU H  89","None","0.84A","5ecoD-5gs3H:undetectable","5ecoD-5gs3H:17.63"],["5L4E_D_EDPD402_1","PROTON-GATED ION CHANNEL;PROTON-GATED ION CHANNEL;PROTON-GATED ION CHANNEL;PROTON-GATED ION CHANNEL;PROTON-GATED ION CHANNEL","5gs3","DIABODY PROTEIN","Homo sapiens",4,"THR H 198;SER H 187;THR H 196;SER H 189","None","0.96A","5l4eA-5gs3H:undetectable;5l4eB-5gs3H:undetectable;5l4eC-5gs3H:undetectable;5l4eD-5gs3H:undetectable;5l4eE-5gs3H:undetectable","5l4eA-5gs3H:20.06;5l4eB-5gs3H:20.06;5l4eC-5gs3H:20.06;5l4eD-5gs3H:20.06;5l4eE-5gs3H:20.06"]]