SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gsz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 5gsz KINESIN-LIKE PROTEIN
KIF19
(Mus
musculus) 		4 / 6 ALA A  83
PHE A  71
ILE A 320
VAL A 318
 None
 0.88A 2cizA-5gszA:
undetectable		 2cizA-5gszA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 5gsz KINESIN-LIKE PROTEIN
KIF19
(Mus
musculus) 		5 / 12 ILE A 179
VAL A 223
LEU A 151
ARG A 245
ALA A 227
 None
 1.32A 2jj8C-5gszA:
undetectable		 2jj8C-5gszA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)		 5gsz KINESIN-LIKE PROTEIN
KIF19
(Mus
musculus) 		3 / 3 GLY A  91
TYR A  96
SER A  94
 None
 0.62A 2xatA-5gszA:
undetectable		 2xatA-5gszA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 5gsz KINESIN-LIKE PROTEIN
KIF19
(Mus
musculus) 		5 / 10 HIS A 221
VAL A 223
PHE A 247
LEU A 307
THR A 304
 None
 1.34A 3zncA-5gszA:
undetectable		 3zncA-5gszA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5gsz KINESIN-LIKE PROTEIN
KIF19
(Mus
musculus) 		5 / 12 GLY A 341
PHE A  67
LYS A  63
SER A 324
LEU A  16
 None
 1.49A 4a83A-5gszA:
undetectable		 4a83A-5gszA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5gsz KINESIN-LIKE PROTEIN
KIF19
(Mus
musculus) 		4 / 8 ASP A 250
ASN A 203
ARG A 206
GLY A 109
 MG  A 402 ( 3.9A)
None
MG  A 402 ( 4.3A)
ADP  A 401 (-3.1A)
 0.93A 4af0A-5gszA:
undetectable		 4af0A-5gszA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYK_B_IMNB300_1
(LACTOYLGLUTATHIONE
LYASE)		 5gsz KINESIN-LIKE PROTEIN
KIF19
(Mus
musculus) 		5 / 12 ALA A 227
PHE A 247
LEU A 307
GLY A 183
LEU A 171
 None
 1.04A 4kykA-5gszA:
1.1
4kykB-5gszA:
1.2		 4kykA-5gszA:
19.78
4kykB-5gszA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA810_1
(CATALASE-PEROXIDASE)		 5gsz KINESIN-LIKE PROTEIN
KIF19
(Mus
musculus) 		4 / 6 HIS A  35
LEU A  44
PRO A  47
SER A 327
 None
 1.27A 5syjA-5gszA:
undetectable		 5syjA-5gszA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB810_1
(CATALASE-PEROXIDASE)		 5gsz KINESIN-LIKE PROTEIN
KIF19
(Mus
musculus) 		4 / 6 HIS A  35
LEU A  44
PRO A  47
SER A 327
 None
 1.24A 5syjB-5gszA:
undetectable		 5syjB-5gszA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 5gsz KINESIN-LIKE PROTEIN
KIF19
(Mus
musculus) 		5 / 12 LEU A 224
PHE A 247
SER A 310
LEU A 128
THR A 127
 None
 1.19A 6b52A-5gszA:
undetectable		 6b52A-5gszA:
20.06