SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gt5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 12 ILE A 117
ALA A 116
ALA A 115
PHE A 132
LEU A  39
 None
 0.91A 1fm6A-5gt5A:
undetectable		 1fm6A-5gt5A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 12 ILE A 117
ALA A 116
ALA A 115
PHE A 132
LEU A  39
 None
 0.92A 1fm9A-5gt5A:
undetectable		 1fm9A-5gt5A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKW_A_EFZA2000_1
(POL POLYPROTEIN)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 10 LEU A 176
LYS A 171
TYR A 270
GLY A 195
TYR A 153
 None
 1.48A 1ikwA-5gt5A:
undetectable		 1ikwA-5gt5A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 12 ILE A 117
ALA A 116
ALA A 115
PHE A 132
LEU A  39
 None
 0.91A 1k74A-5gt5A:
undetectable		 1k74A-5gt5A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		3 / 3 ASP A 147
ASP A 139
LYS A 245
 None
 0.91A 1lqtB-5gt5A:
undetectable		 1lqtB-5gt5A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		3 / 3 ASP A 147
ASP A 139
LYS A 245
 None
 0.92A 1lquB-5gt5A:
undetectable		 1lquB-5gt5A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 11 PHE A 169
SER A 191
LEU A 156
VAL A 119
VAL A 186
 None
 1.39A 1q23L-5gt5A:
undetectable		 1q23L-5gt5A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 11 PHE A 193
SER A 191
LEU A 156
VAL A 119
VAL A 186
 None
 1.30A 1q23L-5gt5A:
undetectable		 1q23L-5gt5A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		4 / 7 LEU A 224
LEU A 231
SER A 232
VAL A 204
 None
 0.93A 1tyrB-5gt5A:
undetectable		 1tyrB-5gt5A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 12 ILE A 117
ALA A 116
ALA A 115
PHE A 132
LEU A  39
 None
 0.96A 1xdkE-5gt5A:
undetectable		 1xdkE-5gt5A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 12 ILE A 117
ALA A 116
ALA A 115
PHE A 132
LEU A  39
 None
 0.95A 1xiuA-5gt5A:
undetectable		 1xiuA-5gt5A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 12 ILE A 117
ALA A 116
ALA A 115
PHE A 132
LEU A  39
 None
 1.01A 1xiuB-5gt5A:
undetectable		 1xiuB-5gt5A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 12 ILE A 117
ALA A 116
ALA A 115
PHE A 132
LEU A  39
 None
 0.95A 1xlsA-5gt5A:
undetectable		 1xlsA-5gt5A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 12 ILE A 117
ALA A 116
ALA A 115
PHE A 132
LEU A  39
 None
 0.95A 1xlsB-5gt5A:
undetectable		 1xlsB-5gt5A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 12 ILE A 117
ALA A 116
ALA A 115
PHE A 132
LEU A  39
 None
 0.95A 1xlsC-5gt5A:
undetectable		 1xlsC-5gt5A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 12 ILE A 117
ALA A 116
ALA A 115
PHE A 132
LEU A  39
 None
 0.95A 1xlsD-5gt5A:
undetectable		 1xlsD-5gt5A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		3 / 3 THR A  89
GLU A 137
HIS A  77
 None
 0.83A 1xwfA-5gt5A:
undetectable		 1xwfA-5gt5A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		3 / 3 THR A  89
GLU A 137
HIS A  77
 None
 0.84A 1xwfB-5gt5A:
undetectable		 1xwfB-5gt5A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		3 / 3 THR A  89
GLU A 137
HIS A  77
 None
 0.82A 1xwfC-5gt5A:
undetectable		 1xwfC-5gt5A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		4 / 7 ALA A 333
ASN A 402
PHE A 404
LEU A 280
 None
 1.06A 2hzqA-5gt5A:
undetectable		 2hzqA-5gt5A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZTH_A_SAMA305_1
(CATECHOL
O-METHYLTRANSFERASE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		3 / 3 SER A 122
GLU A 157
ASP A  97
 None
 0.84A 2zthA-5gt5A:
undetectable		 2zthA-5gt5A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		3 / 3 SER A 122
GLU A 157
ASP A  97
 None
 0.80A 3bwmA-5gt5A:
undetectable		 3bwmA-5gt5A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_1
(COMT PROTEIN)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		3 / 3 SER A 122
GLU A 157
ASP A  97
 None
 0.79A 3bwyA-5gt5A:
undetectable		 3bwyA-5gt5A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		4 / 7 ILE A 126
LYS A 438
MET A  55
LYS A  32
 None
 1.14A 3sj0X-5gt5A:
undetectable		 3sj0X-5gt5A:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 10 PHE A 193
SER A 191
LEU A 156
VAL A 119
VAL A 186
 None
 1.28A 3u9fE-5gt5A:
undetectable		 3u9fE-5gt5A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 10 PHE A 169
SER A 191
LEU A 156
VAL A 119
VAL A 186
 None
 1.33A 3u9fI-5gt5A:
undetectable		 3u9fI-5gt5A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 10 PHE A 193
SER A 191
LEU A 156
VAL A 119
VAL A 186
 None
 1.33A 3u9fI-5gt5A:
undetectable		 3u9fI-5gt5A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 10 PHE A 169
SER A 191
LEU A 156
VAL A 119
VAL A 186
 None
 1.26A 3u9fK-5gt5A:
undetectable		 3u9fK-5gt5A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 10 PHE A 193
SER A 191
LEU A 156
VAL A 119
VAL A 186
 None
 1.34A 3u9fK-5gt5A:
undetectable		 3u9fK-5gt5A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 11 PHE A 193
SER A 191
LEU A 156
VAL A 119
VAL A 186
 None
 1.37A 3u9fN-5gt5A:
undetectable
3u9fO-5gt5A:
undetectable		 3u9fN-5gt5A:
17.56
3u9fO-5gt5A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_P_CLMP221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 9 PHE A 193
SER A 191
LEU A 156
VAL A 119
VAL A 186
 None
 1.27A 3u9fP-5gt5A:
undetectable		 3u9fP-5gt5A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 10 PHE A 193
SER A 191
LEU A 156
VAL A 119
VAL A 186
 None
 1.28A 3u9fR-5gt5A:
undetectable		 3u9fR-5gt5A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 12 ILE A 273
GLY A 175
GLY A 246
ILE A 154
ALA A 172
 None
 0.92A 3uj7B-5gt5A:
undetectable		 3uj7B-5gt5A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 12 PHE A  12
HIS A 266
GLY A  11
ALA A 333
ASN A 402
 None
 1.28A 3v3oB-5gt5A:
undetectable		 3v3oB-5gt5A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 12 LEU A 156
SER A 159
ILE A 104
VAL A 125
LEU A 102
 None
 1.09A 3w68A-5gt5A:
undetectable		 3w68A-5gt5A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		3 / 3 ASP A 178
ARG A 276
ASP A 150
 None
 0.71A 4fzvA-5gt5A:
undetectable		 4fzvA-5gt5A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		4 / 7 LEU A 130
LYS A 438
MET A  55
LYS A  32
 None
 0.99A 4hbfA-5gt5A:
undetectable		 4hbfA-5gt5A:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		4 / 8 ASN A  59
GLU A 134
GLU A  64
TYR A 173
 None
 0.91A 4mj8A-5gt5A:
undetectable
4mj8C-5gt5A:
undetectable		 4mj8A-5gt5A:
17.71
4mj8C-5gt5A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP6_A_B40A601_1
(TRANSPORTER)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		4 / 5 VAL A 177
ASP A 178
PHE A 193
GLY A 246
 None
 1.08A 4xp6A-5gt5A:
undetectable		 4xp6A-5gt5A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		3 / 3 SER A 122
GLU A 157
ASP A  97
 None
 0.81A 4xudA-5gt5A:
undetectable		 4xudA-5gt5A:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		3 / 3 ALA A 257
ASN A 260
LEU A 261
 None
 0.34A 5i1nB-5gt5A:
undetectable		 5i1nB-5gt5A:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		4 / 8 SER A 339
HIS A 267
ASN A 289
HIS A 266
 None
 0.78A 5m8rB-5gt5A:
undetectable		 5m8rB-5gt5A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		4 / 8 SER A 339
HIS A 267
ASN A 289
HIS A 266
 None
 0.82A 5m8rD-5gt5A:
undetectable		 5m8rD-5gt5A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIO_B_LOCB502_1
(TUBULIN BETA CHAIN)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 12 ALA A  40
LEU A  43
ILE A  54
LYS A  31
ILE A 104
 None
 0.97A 5mioB-5gt5A:
undetectable		 5mioB-5gt5A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_D_SAMD501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 10 LEU A 265
HIS A 266
ILE A 263
GLY A  11
ALA A 285
 None
 1.05A 5o96C-5gt5A:
undetectable
5o96D-5gt5A:
undetectable		 5o96C-5gt5A:
20.54
5o96D-5gt5A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		3 / 3 GLY A  90
LEU A  86
HIS A 114
 None
 0.62A 5u63A-5gt5A:
undetectable		 5u63A-5gt5A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		3 / 3 GLY A  90
LEU A  86
HIS A 114
 None
 0.62A 5u63B-5gt5A:
undetectable		 5u63B-5gt5A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 12 ILE A 117
ALA A 116
ALA A 115
PHE A 132
LEU A  39
 None
 1.00A 5uanA-5gt5A:
undetectable		 5uanA-5gt5A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		4 / 4 LEU A 102
GLY A 101
SER A 123
SER A 122
 None
 1.15A 5uunA-5gt5A:
undetectable		 5uunA-5gt5A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		4 / 4 LEU A 102
GLY A 101
SER A 123
SER A 122
 None
 1.20A 5uunB-5gt5A:
undetectable		 5uunB-5gt5A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 12 ILE A 117
ALA A 116
ALA A 115
PHE A 132
LEU A  39
 None
 0.97A 5z12B-5gt5A:
undetectable		 5z12B-5gt5A:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 12 ILE A 117
ALA A 116
ALA A 115
PHE A 132
LEU A  39
 None
 0.93A 5z12C-5gt5A:
undetectable		 5z12C-5gt5A:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		3 / 3 ASP A 178
ARG A 276
ASP A 150
 None
 0.74A 5zvgA-5gt5A:
undetectable		 5zvgA-5gt5A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		3 / 3 ASP A 178
ARG A 276
ASP A 150
 None
 0.79A 5zvgB-5gt5A:
undetectable		 5zvgB-5gt5A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 12 ILE A 117
ALA A 116
ALA A 115
PHE A 132
LEU A  39
 None
 0.95A 6a5yD-5gt5A:
undetectable		 6a5yD-5gt5A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 12 ILE A 117
ALA A 116
ALA A 115
PHE A 132
LEU A  39
 None
 0.94A 6a5zL-5gt5A:
undetectable		 6a5zL-5gt5A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 12 ILE A 117
ALA A 116
ALA A 115
PHE A 132
LEU A  39
 None
 0.98A 6a60D-5gt5A:
undetectable		 6a60D-5gt5A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 12 ILE A 188
PHE A 193
GLY A 430
ALA A 429
ILE A 290
 None
 1.11A 6dwnD-5gt5A:
undetectable		 6dwnD-5gt5A:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_E_ZOLE401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		4 / 4 LEU A 248
ASP A 178
ASP A 152
ARG A 276
 None
 1.46A 6g31E-5gt5A:
undetectable		 6g31E-5gt5A:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_2
(-)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		4 / 8 VAL A 336
HIS A 267
ASN A 268
TYR A 270
 None
 1.17A 6gneB-5gt5A:
undetectable		 6gneB-5gt5A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_1
(-)		 5gt5 PECTATE LYASE
(Paenibacillus
sp.
0602) 		5 / 12 TYR A 146
TRP A 138
HIS A  83
VAL A  85
GLY A  90
 None
 1.46A 6gngB-5gt5A:
undetectable		 6gngB-5gt5A:
22.28