SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gus'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TMZ_A_06XA504_1 (CYTOCHROME P450 2B4)	5gus	HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN (Zymomonas mobilis)	5 / 9	LEU A 116 LEU A 140 ILE A 44 PHE A 123 GLU A 9	None	1.48A	3tmzA-5gusA: undetectable	3tmzA-5gusA: 17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DTA_A_ADNA401_1 (APH(2'')-ID)	5gus	HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN (Zymomonas mobilis)	5 / 10	ALA A 10 ILE A 44 ILE A 22 LEU A 14 ILE A 46	None	1.21A	4dtaA-5gusA: undetectable	4dtaA-5gusA: 17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RVD_A_SAMA502_0 (D-MYCAROSE 3-C-METHYLTRANSFERAS E)	5gus	HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN (Zymomonas mobilis)	5 / 12	ILE A 46 GLY A 57 PRO A 110 HIS A 105 VAL A 23	None	1.07A	4rvdA-5gusA: undetectable	4rvdA-5gusA: 17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGD_A_ACTA812_0 (GEPHYRIN)	5gus	HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN (Zymomonas mobilis)	4 / 6	GLU A 9 ARG A 43 PHE A 58 VAL A 55	None	1.47A	6fgdA-5gusA: undetectable	6fgdA-5gusA: 17.44

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3TMZ_A_06XA504_1","CYTOCHROME P450 2B4","5gus","HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN","Zymomonas mobilis",5,"LEU A 116;LEU A 140;ILE A  44;PHE A 123;GLU A   9","None","1.48A","3tmzA-5gusA:undetectable","3tmzA-5gusA:17.21"],["4DTA_A_ADNA401_1","APH(2'')-ID","5gus","HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN","Zymomonas mobilis",5,"ALA A  10;ILE A  44;ILE A  22;LEU A  14;ILE A  46","None","1.21A","4dtaA-5gusA:undetectable","4dtaA-5gusA:17.82"],["4RVD_A_SAMA502_0","D-MYCAROSE 3-C-METHYLTRANSFERASE","5gus","HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN","Zymomonas mobilis",5,"ILE A  46;GLY A  57;PRO A 110;HIS A 105;VAL A  23","None","1.07A","4rvdA-5gusA:undetectable","4rvdA-5gusA:17.06"],["6FGD_A_ACTA812_0","GEPHYRIN","5gus","HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN","Zymomonas mobilis",4,"GLU A   9;ARG A  43;PHE A  58;VAL A  55","None","1.47A","6fgdA-5gusA:undetectable","6fgdA-5gusA:17.44"]]