SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gv0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP6_B_SALB3003_1 (TRANSCRIPTIONAL REGULATOR TCAR)	5gv0	LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 (Mus musculus)	4 / 6	ILE A 333 VAL A 335 LEU A 339 LEU A 231	None	0.82A	3kp6A-5gv0A: undetectable 3kp6B-5gv0A: undetectable	3kp6A-5gv0A: 22.16 3kp6B-5gv0A: 22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KIR_B_RCXB601_2 (PROSTAGLANDIN G/H SYNTHASE 2)	5gv0	LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 (Mus musculus)	4 / 4	LEU A 299 ARG A 273 ILE A 233 PHE A 247	None	1.36A	5kirB-5gv0A: undetectable	5kirB-5gv0A: 14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OH1_C_9UQC202_0 (CEREBLON ISOFORM 4)	5gv0	LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 (Mus musculus)	4 / 8	ASN A 248 PRO A 208 PHE A 344 TYR A 213	None	1.41A	5oh1C-5gv0A: undetectable	5oh1C-5gv0A: 21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V0V_A_8QPA612_1 (SERUM ALBUMIN)	5gv0	LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 (Mus musculus)	5 / 12	GLU A 330 LEU A 277 LEU A 341 LEU A 231 ILE A 249	None	1.08A	5v0vA-5gv0A: undetectable	5v0vA-5gv0A: 13.77

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3KP6_B_SALB3003_1","TRANSCRIPTIONAL REGULATOR TCAR;TRANSCRIPTIONAL REGULATOR TCAR","5gv0","LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1","Mus musculus",4,"ILE A 333;VAL A 335;LEU A 339;LEU A 231","None","0.82A","3kp6A-5gv0A:undetectable;3kp6B-5gv0A:undetectable","3kp6A-5gv0A:22.16;3kp6B-5gv0A:22.16"],["5KIR_B_RCXB601_2","PROSTAGLANDIN G\/H SYNTHASE 2","5gv0","LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1","Mus musculus",4,"LEU A 299;ARG A 273;ILE A 233;PHE A 247","None","1.36A","5kirB-5gv0A:undetectable","5kirB-5gv0A:14.39"],["5OH1_C_9UQC202_0","CEREBLON ISOFORM 4","5gv0","LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1","Mus musculus",4,"ASN A 248;PRO A 208;PHE A 344;TYR A 213","None","1.41A","5oh1C-5gv0A:undetectable","5oh1C-5gv0A:21.18"],["5V0V_A_8QPA612_1","SERUM ALBUMIN","5gv0","LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1","Mus musculus",5,"GLU A 330;LEU A 277;LEU A 341;LEU A 231;ILE A 249","None","1.08A","5v0vA-5gv0A:undetectable","5v0vA-5gv0A:13.77"]]