SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gvi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 10 GLY A 441
HIS A 434
HIS A 435
ALA A  73
SER A  77
 None
 1.29A 1utdN-5gviA:
undetectable
1utdO-5gviA:
undetectable		 1utdN-5gviA:
11.54
1utdO-5gviA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 10 GLY A 441
HIS A 434
HIS A 435
ALA A  73
SER A  77
 None
 1.29A 1utdR-5gviA:
undetectable
1utdS-5gviA:
undetectable		 1utdR-5gviA:
11.54
1utdS-5gviA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_2
(CES1 PROTEIN)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		4 / 4 LEU A 310
PRO A 252
ILE A 319
LEU A 247
 None
 1.11A 1ya4B-5gviA:
undetectable		 1ya4B-5gviA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 11 LEU A 247
SER A 346
LEU A 347
LEU A 317
ARG A 491
 None
 1.00A 2ceoA-5gviA:
undetectable		 2ceoA-5gviA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		4 / 5 ALA A 430
TRP A 463
LEU A 428
MET A 492
 None
 1.17A 2oaxA-5gviA:
undetectable		 2oaxA-5gviA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_A_FOLA401_0
(DIHYDROFOLATE
REDUCTASE)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 12 ILE A 270
LEU A 313
PHE A 244
ILE A 319
LEU A 249
 None
 1.08A 2w3bA-5gviA:
undetectable		 2w3bA-5gviA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_0
(DIHYDROFOLATE
REDUCTASE)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 12 ILE A 270
LEU A 313
PHE A 244
ILE A 319
LEU A 249
 None
 1.07A 2w3bB-5gviA:
undetectable		 2w3bB-5gviA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_1
(HYPOTHETICAL PROTEIN)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		4 / 4 GLY A 441
GLU A 155
ASP A 157
TYR A 485
 None
 1.36A 2yvlC-5gviA:
undetectable		 2yvlC-5gviA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		4 / 6 TRP A 465
ASN A  76
ALA A  73
HIS A 442
 None
 1.35A 3aruA-5gviA:
undetectable		 3aruA-5gviA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		4 / 8 LEU A 487
VAL A 479
LEU A 262
TYR A 489
 None
 1.05A 3v81C-5gviA:
undetectable		 3v81C-5gviA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KEB_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 12 ILE A 270
LEU A 313
PHE A 244
ILE A 319
LEU A 249
 None
 1.09A 4kebB-5gviA:
undetectable		 4kebB-5gviA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFJ_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 12 ILE A 270
LEU A 313
PHE A 244
ILE A 319
LEU A 249
 None
 1.06A 4kfjB-5gviA:
undetectable		 4kfjB-5gviA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 12 ILE A 270
LEU A 313
PHE A 244
ILE A 319
LEU A 249
 None
 1.05A 4m6kA-5gviA:
undetectable		 4m6kA-5gviA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		4 / 4 LEU A 321
SER A 248
LEU A 486
LEU A 262
 None
 0.97A 4n09A-5gviA:
undetectable		 4n09A-5gviA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_C_IPHC101_0
(INSULIN)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 11 LEU A 119
LEU A 139
ALA A 136
LEU A  66
LEU A 161
 None
 1.14A 4p65C-5gviA:
undetectable
4p65D-5gviA:
undetectable
4p65J-5gviA:
undetectable
4p65L-5gviA:
undetectable		 4p65C-5gviA:
5.17
4p65D-5gviA:
5.74
4p65J-5gviA:
5.74
4p65L-5gviA:
5.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_G_IPHG101_0
(INSULIN)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 11 LEU A  66
LEU A 161
LEU A 119
LEU A 139
ALA A 136
 None
 1.04A 4p65B-5gviA:
undetectable
4p65D-5gviA:
undetectable
4p65G-5gviA:
undetectable
4p65H-5gviA:
undetectable		 4p65B-5gviA:
5.74
4p65D-5gviA:
5.74
4p65G-5gviA:
5.17
4p65H-5gviA:
5.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		4 / 8 LEU A 487
VAL A 479
LEU A 262
TYR A 489
 None
 1.00A 4pwdC-5gviA:
undetectable		 4pwdC-5gviA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		4 / 8 LEU A 347
THR A 342
LEU A 262
LEU A 266
 None
 0.77A 4z90F-5gviA:
undetectable
4z90G-5gviA:
undetectable
4z90H-5gviA:
undetectable
4z90I-5gviA:
undetectable
4z90J-5gviA:
undetectable		 4z90F-5gviA:
19.35
4z90G-5gviA:
19.35
4z90H-5gviA:
19.35
4z90I-5gviA:
19.35
4z90J-5gviA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 10 GLY A 441
HIS A 434
HIS A 435
ALA A  73
SER A  77
 None
 1.32A 5eeuR-5gviA:
undetectable
5eeuS-5gviA:
undetectable		 5eeuR-5gviA:
11.54
5eeuS-5gviA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 10 GLY A 441
HIS A 434
HIS A 435
ALA A  73
SER A  77
 None
 1.32A 5eeuT-5gviA:
undetectable
5eeuU-5gviA:
undetectable		 5eeuT-5gviA:
11.54
5eeuU-5gviA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 10 GLY A 441
HIS A 434
HIS A 435
ALA A  73
SER A  77
 None
 1.31A 5eevR-5gviA:
undetectable
5eevS-5gviA:
undetectable		 5eevR-5gviA:
11.54
5eevS-5gviA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 10 GLY A 441
HIS A 434
HIS A 435
ALA A  73
SER A  77
 None
 1.31A 5eewR-5gviA:
undetectable
5eewS-5gviA:
undetectable		 5eewR-5gviA:
11.54
5eewS-5gviA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 10 GLY A 441
HIS A 434
HIS A 435
ALA A  73
SER A  77
 None
 1.31A 5eexR-5gviA:
undetectable
5eexS-5gviA:
undetectable		 5eexR-5gviA:
11.54
5eexS-5gviA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 10 GLY A 441
HIS A 434
HIS A 435
ALA A  73
SER A  77
 None
 1.31A 5eeyR-5gviA:
undetectable
5eeyS-5gviA:
undetectable		 5eeyR-5gviA:
11.54
5eeyS-5gviA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 10 GLY A 441
HIS A 434
HIS A 435
ALA A  73
SER A  77
 None
 1.31A 5eezR-5gviA:
undetectable
5eezS-5gviA:
undetectable		 5eezR-5gviA:
11.54
5eezS-5gviA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 10 GLY A 441
HIS A 434
HIS A 435
ALA A  73
SER A  77
 None
 1.31A 5ef0R-5gviA:
undetectable
5ef0S-5gviA:
undetectable		 5ef0R-5gviA:
11.54
5ef0S-5gviA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 10 GLY A 441
HIS A 434
HIS A 435
ALA A  73
SER A  77
 None
 1.30A 5ef1P-5gviA:
undetectable
5ef1Q-5gviA:
undetectable		 5ef1P-5gviA:
11.54
5ef1Q-5gviA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 10 GLY A 441
HIS A 434
HIS A 435
ALA A  73
SER A  77
 None
 1.31A 5ef1R-5gviA:
undetectable
5ef1S-5gviA:
undetectable		 5ef1R-5gviA:
11.54
5ef1S-5gviA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 10 GLY A 441
HIS A 434
HIS A 435
ALA A  73
SER A  77
 None
 1.30A 5ef2P-5gviA:
undetectable
5ef2Q-5gviA:
undetectable		 5ef2P-5gviA:
11.54
5ef2Q-5gviA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 10 GLY A 441
HIS A 434
HIS A 435
ALA A  73
SER A  77
 None
 1.31A 5ef2R-5gviA:
undetectable
5ef2S-5gviA:
undetectable		 5ef2R-5gviA:
11.54
5ef2S-5gviA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 10 GLY A 441
HIS A 434
HIS A 435
ALA A  73
SER A  77
 None
 1.30A 5ef3P-5gviA:
undetectable
5ef3Q-5gviA:
undetectable		 5ef3P-5gviA:
11.54
5ef3Q-5gviA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 10 GLY A 441
HIS A 434
HIS A 435
ALA A  73
SER A  77
 None
 1.31A 5ef3R-5gviA:
undetectable
5ef3S-5gviA:
undetectable		 5ef3R-5gviA:
11.54
5ef3S-5gviA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 10 GLY A 441
HIS A 434
HIS A 435
ALA A  73
SER A  77
 None
 1.31A 5ef3S-5gviA:
undetectable
5ef3T-5gviA:
undetectable		 5ef3S-5gviA:
11.54
5ef3T-5gviA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 10 GLY A 441
HIS A 434
HIS A 435
ALA A  73
SER A  77
 None
 1.32A 5ef3T-5gviA:
undetectable
5ef3U-5gviA:
undetectable		 5ef3T-5gviA:
11.54
5ef3U-5gviA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_2
(ESTROGEN RECEPTOR)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		4 / 5 LEU A  82
LEU A 139
PHE A  88
LEU A 169
 None
 0.90A 5gtrA-5gviA:
undetectable		 5gtrA-5gviA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 8 GLY A  65
LEU A  66
ASN A  76
SER A  77
GLN A  80
 None
 0.60A 5xu8A-5gviA:
31.3		 5xu8A-5gviA:
27.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30
(Danio
rerio) 		5 / 12 LEU A 432
HIS A 442
ARG A 447
GLY A  65
LEU A  66
 None
 0.99A 6b0lB-5gviA:
undetectable		 6b0lB-5gviA:
11.47