SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gvt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BCU_H_PRLH280_0
(ALPHA-THROMBIN)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		5 / 9 ASP A 189
ALA A 190
SER A 195
GLY A 216
GLY A 226
 None
 0.46A 1bcuH-5gvtA:
35.5		 1bcuH-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BCU_H_PRLH280_0
(ALPHA-THROMBIN)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		5 / 9 ASP A 189
ALA A 190
SER A 195
TRP A 215
GLY A 226
 None
 1.25A 1bcuH-5gvtA:
35.5		 1bcuH-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETR_H_MITH1_1
(EPSILON-THROMBIN)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		5 / 12 HIS A  57
ASP A 189
SER A 195
GLY A 216
GLY A 226
 None
 0.65A 1etrH-5gvtA:
34.6		 1etrH-5gvtA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F5L_A_AMRA301_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		4 / 8 ASP A 189
SER A 195
GLY A 216
GLY A 226
 None
 0.45A 1f5lA-5gvtA:
34.7		 1f5lA-5gvtA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		4 / 4 LEU A 199
GLY A 184
ASP A 189
TYR A 228
 None
 1.37A 1oxrA-5gvtA:
undetectable		 1oxrA-5gvtA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SS4_A_ACTA411_0
(GLYOXALASE FAMILY
PROTEIN)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		4 / 5 VAL A 138
THR A 139
GLN A  30
ILE A 121
 None
 1.36A 1ss4A-5gvtA:
undetectable		 1ss4A-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TNL_A_TPAA900_1
(TRYPSIN)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		4 / 6 ASP A 189
SER A 195
GLY A 216
GLY A 226
 None
 0.54A 1tnlA-5gvtA:
33.3		 1tnlA-5gvtA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_A_RBFA300_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		5 / 11 GLY A 197
LEU A  33
HIS A  40
ILE A  16
ALA A 190
 None
 1.38A 2a58A-5gvtA:
undetectable
2a58E-5gvtA:
undetectable		 2a58A-5gvtA:
19.63
2a58E-5gvtA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_D_RBFD303_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		5 / 11 ILE A  16
ALA A 190
GLY A 197
LEU A  33
HIS A  40
 None
 1.38A 2a58C-5gvtA:
undetectable
2a58D-5gvtA:
undetectable		 2a58C-5gvtA:
19.63
2a58D-5gvtA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		3 / 3 LYS A  16
ASP A  60
ASP A 194
 None
 0.93A 2br4D-5gvtA:
undetectable		 2br4D-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTV_A_NCAA1301_0
(CATIONIC TRYPSIN)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		4 / 6 ASP A 189
SER A 195
GLY A 216
GLY A 226
 None
 0.49A 2otvA-5gvtA:
33.4		 2otvA-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
LEU A  53
 None
 1.39A 2oxtD-5gvtA:
undetectable		 2oxtD-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_1
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 ASP A 189
ALA A 190
SER A 195
GLY A 216
GLY A 226
TYR A 228
 None
 0.32A 2p16A-5gvtA:
35.3		 2p16A-5gvtA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_1
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 ASP A 189
ALA A 190
SER A 195
TRP A 215
GLY A 226
TYR A 228
 None
 1.14A 2p16A-5gvtA:
35.3		 2p16A-5gvtA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
VAL A  52
 None
 1.36A 2pxcA-5gvtA:
undetectable		 2pxcA-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		4 / 8 ILE A 181
GLY A 211
LEU A 209
LEU A 123
 None
 0.80A 2vctA-5gvtA:
undetectable		 2vctA-5gvtA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		4 / 8 ILE A 181
GLY A 211
LEU A 209
LEU A 123
 None
 0.83A 2vctB-5gvtA:
undetectable		 2vctB-5gvtA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		4 / 8 ILE A 181
GLY A 211
LEU A 209
LEU A 123
 None
 0.86A 2vctC-5gvtA:
undetectable		 2vctC-5gvtA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W26_A_RIVA1001_1
(ACTIVATED FACTOR XA
HEAVY CHAIN)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		7 / 12 ASP A 189
ALA A 190
SER A 195
GLY A 216
GLY A 219
GLY A 226
TYR A 228
 None
 0.71A 2w26A-5gvtA:
35.3		 2w26A-5gvtA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W26_A_RIVA1001_1
(ACTIVATED FACTOR XA
HEAVY CHAIN)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 ASP A 189
ALA A 190
SER A 195
TRP A 215
GLY A 226
TYR A 228
 None
 1.16A 2w26A-5gvtA:
35.3		 2w26A-5gvtA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GY3_A_PNTA246_0
(CATIONIC TRYPSIN)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		5 / 11 HIS A  57
ASP A 189
SER A 195
GLY A 216
GLY A 226
 None
 0.56A 3gy3A-5gvtA:
11.9		 3gy3A-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GY3_A_PNTA246_0
(CATIONIC TRYPSIN)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		5 / 11 HIS A  57
ASP A 189
SER A 195
TRP A 215
GLY A 226
 None
 1.19A 3gy3A-5gvtA:
11.9		 3gy3A-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		5 / 12 HIS A  57
ASP A 102
LYS A 192
GLY A 193
SER A 195
 None
 0.97A 3keeD-5gvtA:
11.2		 3keeD-5gvtA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
VAL A  52
 None
 1.26A 3p97C-5gvtA:
undetectable		 3p97C-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		3 / 3 TRP A 137
TRP A  27
THR A 139
 None
 1.42A 4bboB-5gvtA:
undetectable		 4bboB-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
VAL A  52
 None
 1.27A 4ctjA-5gvtA:
undetectable		 4ctjA-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
VAL A  52
 None
 1.25A 4ctjC-5gvtA:
undetectable		 4ctjC-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
VAL A  52
 None
 1.29A 4ctkA-5gvtA:
undetectable		 4ctkA-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
VAL A  52
 None
 1.25A 4ctkC-5gvtA:
undetectable		 4ctkC-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		5 / 10 LEU A  53
ILE A 106
ILE A 212
GLY A 197
GLY A  43
 None
 0.95A 4fakA-5gvtA:
undetectable		 4fakA-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		3 / 3 ASP A 102
TRP A  65
SER A 195
 None
 0.98A 4lrhB-5gvtA:
undetectable		 4lrhB-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		3 / 3 ASP A 102
TRP A  65
SER A 195
 None
 1.04A 4lrhF-5gvtA:
undetectable		 4lrhF-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		4 / 6 LEU A 155
ILE A 154
LYS A 157
GLU A  26
 None
 0.95A 4w5nA-5gvtA:
undetectable		 4w5nA-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		5 / 9 PRO A 198
LEU A  33
ILE A 212
LEU A  53
THR A  54
 None
 1.24A 4x3mB-5gvtA:
undetectable		 4x3mB-5gvtA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
VAL A  52
 None
 1.28A 5e9qA-5gvtA:
undetectable		 5e9qA-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
VAL A  52
 None
 1.26A 5e9qC-5gvtA:
undetectable		 5e9qC-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
VAL A  52
 None
 1.25A 5ec8C-5gvtA:
undetectable		 5ec8C-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
VAL A  52
 None
 1.29A 5ehgA-5gvtA:
undetectable		 5ehgA-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
VAL A  52
 None
 1.26A 5ehgC-5gvtA:
undetectable		 5ehgC-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
VAL A  52
 None
 1.27A 5eifA-5gvtA:
undetectable		 5eifA-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
VAL A  52
 None
 1.25A 5eifC-5gvtA:
undetectable		 5eifC-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
VAL A  52
 None
 1.25A 5eiwC-5gvtA:
undetectable		 5eiwC-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
VAL A  52
 None
 1.26A 5ekxB-5gvtA:
undetectable		 5ekxB-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
VAL A  52
 None
 1.30A 5kqrA-5gvtA:
undetectable		 5kqrA-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		5 / 10 LEU A 155
GLY A  44
GLY A 197
ILE A  70
LEU A  33
 None
 0.99A 5l0zB-5gvtA:
undetectable		 5l0zB-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
VAL A  52
 None
 1.26A 5m5bA-5gvtA:
undetectable		 5m5bA-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
VAL A  52
 None
 1.28A 5njvA-5gvtA:
undetectable		 5njvA-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_B_SAMB301_0
(NS5)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
VAL A  52
 None
 1.29A 5njvB-5gvtA:
undetectable		 5njvB-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 5gvt PLASMA KALLIKREIN
(Mus
musculus) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
VAL A  52
 None
 1.33A 5wz1B-5gvtA:
undetectable		 5wz1B-5gvtA:
undetectable