SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gw7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 12 ASP A 362
PHE A 365
ALA A 442
GLY A 441
HIS A 448
 None
 1.49A 1a4lD-5gw7A:
undetectable		 1a4lD-5gw7A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		3 / 3 VAL A 686
VAL A 684
TRP A 744
 None
 0.89A 1bdwA-5gw7A:
undetectable
1bdwB-5gw7A:
undetectable		 1bdwA-5gw7A:
1.76
1bdwB-5gw7A:
1.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		3 / 3 TRP A 350
VAL A 366
TRP A 385
 None
 1.08A 1c4dA-5gw7A:
undetectable
1c4dB-5gw7A:
undetectable		 1c4dA-5gw7A:
1.76
1c4dB-5gw7A:
1.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 8 PHE A  66
ILE A  64
PHE A  33
HIS A  41
LEU A  42
 None
 1.24A 1fslB-5gw7A:
undetectable		 1fslB-5gw7A:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_0
(HYPOTHETICAL PROTEIN
RV2118C)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 12 ILE A 591
GLY A 631
SER A 550
ALA A 554
VAL A 651
 None
 1.23A 1i9gA-5gw7A:
undetectable		 1i9gA-5gw7A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		4 / 8 PHE A 691
TYR A 556
LEU A 394
TRP A 397
 None
 1.01A 1rmtD-5gw7A:
undetectable		 1rmtD-5gw7A:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0F_A_STRA1499_1
(CYTOCHROME P450 3A4)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		4 / 4 PHE A 602
ASP A 597
PHE A 596
VAL A 648
 None
 1.27A 1w0fA-5gw7A:
undetectable		 1w0fA-5gw7A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 10 TYR A  63
ARG A 313
TYR A 160
THR A 184
ALA A 183
 None
 1.48A 2coiA-5gw7A:
undetectable
2coiB-5gw7A:
undetectable		 2coiA-5gw7A:
21.13
2coiB-5gw7A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 10 TYR A  63
ARG A 313
TYR A 160
THR A 184
ALA A 183
 None
 1.50A 2coiA-5gw7A:
undetectable
2coiB-5gw7A:
undetectable		 2coiA-5gw7A:
21.13
2coiB-5gw7A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 12 SER A 238
GLN A 241
LEU A 248
ILE A 244
SER A 229
 None
 1.34A 2fj1A-5gw7A:
undetectable		 2fj1A-5gw7A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		4 / 8 LEU A  42
PRO A 740
SER A 309
GLY A 723
 None
 0.92A 2qd5B-5gw7A:
undetectable		 2qd5B-5gw7A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W13_A_ACTA1208_0
(ZINC
METALLOPROTEINASE
BAP1)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		4 / 4 THR A 213
ARG A 211
GLU A 206
ASN A 208
 None
 0.76A 2w13A-5gw7A:
undetectable		 2w13A-5gw7A:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W1B_A_DXCA2034_0
(ACRIFLAVIN
RESISTANCE PROTEIN B)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		3 / 3 PHE A 348
SER A 398
LEU A 394
 None
 0.78A 2w1bA-5gw7A:
undetectable		 2w1bA-5gw7A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_B_SALB258_1
(TRANSCRIPTIONAL
REGULATOR)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 11 LEU A 266
ILE A  92
PRO A  93
GLY A  94
SER A 258
 None
 1.49A 3bpxA-5gw7A:
undetectable
3bpxB-5gw7A:
undetectable		 3bpxA-5gw7A:
12.16
3bpxB-5gw7A:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		4 / 4 LEU A 224
ALA A 216
VAL A 203
PRO A 202
 None
 1.23A 3gv1B-5gw7A:
undetectable		 3gv1B-5gw7A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		4 / 7 LEU A  42
PRO A 740
SER A 309
GLY A 723
 None
 1.03A 3hcnA-5gw7A:
undetectable		 3hcnA-5gw7A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		4 / 7 LEU A  42
PRO A 740
SER A 309
GLY A 723
 None
 0.94A 3hcrB-5gw7A:
undetectable		 3hcrB-5gw7A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_1
(O-METHYLTRANSFERASE)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		4 / 4 ASP A 136
SER A 214
PHE A 212
SER A  69
 None
 1.39A 3i5uA-5gw7A:
0.0		 3i5uA-5gw7A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		4 / 8 GLU A 263
PHE A  32
SER A  91
ILE A   9
 None
 1.09A 3jz0B-5gw7A:
4.0		 3jz0B-5gw7A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_4
(HIV-1 PROTEASE)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		3 / 3 ARG A 295
VAL A 347
THR A 325
 None
 0.80A 3k4vD-5gw7A:
undetectable		 3k4vD-5gw7A:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		4 / 7 MET A 652
LEU A 708
LEU A 635
PHE A 602
 None
 1.24A 3nk2X-5gw7A:
undetectable		 3nk2X-5gw7A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_B_D16B520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 12 ALA A 668
PHE A 602
PRO A 634
LEU A 664
THR A 670
 None
 1.21A 3nrrB-5gw7A:
undetectable		 3nrrB-5gw7A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7V_A_SAMA992_0
(METHYLORNITHINE
SYNTHASE PYLB)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 12 THR A 305
GLY A  36
ARG A 117
VAL A 301
ALA A 300
 None
 1.08A 3t7vA-5gw7A:
undetectable		 3t7vA-5gw7A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		4 / 7 PHE A 742
GLY A 738
THR A 311
PHE A 315
 BGC  A1003 (-4.2A)
None
None
BGC  A1003 (-4.4A)
 1.09A 3vnsA-5gw7A:
undetectable		 3vnsA-5gw7A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 12 GLY A  51
LEU A 133
ALA A  89
PHE A  85
LEU A  87
 None
 1.11A 3vywA-5gw7A:
undetectable		 3vywA-5gw7A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 12 GLY A  51
LEU A 133
ALA A  89
PHE A  85
LEU A  87
 None
 1.14A 3vywB-5gw7A:
undetectable		 3vywB-5gw7A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 12 GLY A  51
LEU A 133
ALA A  89
PHE A  85
LEU A  87
 None
 1.08A 3vywC-5gw7A:
undetectable		 3vywC-5gw7A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 12 GLY A  51
LEU A 133
ALA A  89
PHE A  85
LEU A  87
 None
 1.08A 3vywD-5gw7A:
undetectable		 3vywD-5gw7A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB504_1
(HEMOLYTIC LECTIN
CEL-III)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		4 / 5 GLU A 697
GLY A 700
TYR A 699
GLN A 642
 None
 1.40A 3w9tB-5gw7A:
undetectable		 3w9tB-5gw7A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD506_1
(HEMOLYTIC LECTIN
CEL-III)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		4 / 5 GLU A 697
GLY A 700
TYR A 699
GLN A 642
 None
 1.42A 3w9tD-5gw7A:
undetectable		 3w9tD-5gw7A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG505_1
(HEMOLYTIC LECTIN
CEL-III)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		4 / 5 GLU A 697
GLY A 700
TYR A 699
GLN A 642
 None
 1.47A 3w9tG-5gw7A:
undetectable		 3w9tG-5gw7A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		3 / 3 ARG A 500
TRP A 632
GLY A 631
 None
 0.94A 4e7cA-5gw7A:
undetectable		 4e7cA-5gw7A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOS_A_4KOA201_1
(UNCHARACTERIZED
PROTEIN)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 12 PRO A  31
GLY A  55
PHE A  33
TYR A 195
LEU A  59
 None
 1.30A 4kosA-5gw7A:
undetectable		 4kosA-5gw7A:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 12 PRO A  31
GLY A  55
PHE A  33
TYR A 195
LEU A  59
 None
 1.30A 4kovA-5gw7A:
undetectable		 4kovA-5gw7A:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOW_A_CFXA204_1
(UNCHARACTERIZED
PROTEIN)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 12 PRO A  31
GLY A  55
PHE A  33
TYR A 195
LEU A  59
 None
 1.33A 4kowA-5gw7A:
undetectable		 4kowA-5gw7A:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOX_A_CLSA205_1
(UNCHARACTERIZED
PROTEIN)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 11 PRO A  31
GLY A  55
PHE A  33
TYR A 195
LEU A  59
 None
 1.28A 4koxA-5gw7A:
undetectable		 4koxA-5gw7A:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		3 / 3 TRP A 294
GLN A 319
THR A 305
 None
 1.00A 4m2xA-5gw7A:
undetectable		 4m2xA-5gw7A:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		4 / 6 LEU A 188
ARG A 313
VAL A 301
ALA A 300
 None
 1.00A 4nkxA-5gw7A:
undetectable		 4nkxA-5gw7A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 12 GLU A 108
LEU A  87
LEU A 224
GLY A  52
PHE A  53
 None
 1.29A 4retC-5gw7A:
undetectable		 4retC-5gw7A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 6 ARG A 500
SER A 633
ARG A 625
GLY A 626
GLU A 624
 None
 1.33A 5cdqA-5gw7A:
undetectable
5cdqC-5gw7A:
0.8
5cdqD-5gw7A:
undetectable		 5cdqA-5gw7A:
20.97
5cdqC-5gw7A:
20.97
5cdqD-5gw7A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		4 / 6 PHE A 742
PRO A 740
THR A 289
ILE A 725
 BGC  A1003 (-4.2A)
None
None
None
 1.21A 5ih0A-5gw7A:
1.7		 5ih0A-5gw7A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		4 / 8 GLY A 626
ASP A 605
GLY A 507
ILE A 509
 None
 0.66A 5kr1B-5gw7A:
undetectable		 5kr1B-5gw7A:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		4 / 8 VAL A 648
GLY A 665
LEU A 664
THR A 660
 None
 1.08A 5sxqB-5gw7A:
undetectable		 5sxqB-5gw7A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		4 / 8 TRP A 323
TRP A 744
THR A 666
TRP A 685
 BGC  A1003 (-3.9A)
None
None
None
 1.42A 5tzoA-5gw7A:
undetectable		 5tzoA-5gw7A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHG_C_RFPC1201_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 12 ASP A  22
HIS A  26
SER A 316
ASN A  65
ILE A  64
 None
 1.49A 5uhgC-5gw7A:
undetectable		 5uhgC-5gw7A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC607_0
(ALPHA-AMYLASE)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 6 GLY A 626
ASP A 597
GLY A 628
PRO A 629
GLY A 631
 None
 1.25A 6ag0C-5gw7A:
undetectable		 6ag0C-5gw7A:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_1
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 12 TYR A 590
ILE A 591
ASN A 615
LEU A 613
SER A 633
 None
 1.45A 6baaE-5gw7A:
0.6		 6baaE-5gw7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_1
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 12 TYR A 590
ILE A 591
ASN A 615
LEU A 613
SER A 633
 None
 1.45A 6baaF-5gw7A:
0.7		 6baaF-5gw7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_1
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 12 TYR A 590
ILE A 591
ASN A 615
LEU A 613
SER A 633
 None
 1.45A 6baaG-5gw7A:
0.6		 6baaG-5gw7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_1
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		5 / 12 TYR A 590
ILE A 591
ASN A 615
LEU A 613
SER A 633
 None
 1.45A 6baaH-5gw7A:
0.6		 6baaH-5gw7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		3 / 3 ARG A 281
LYS A 285
ARG A 295
 None
 1.23A 6c06D-5gw7A:
2.4		 6c06D-5gw7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5gw7 GLUCOSIDASE YGJK
(Escherichia
coli) 		4 / 4 TYR A 604
LEU A 635
TYR A 701
PRO A 634
 None
 1.05A 6e8qA-5gw7A:
0.0		 6e8qA-5gw7A:
7.43