SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gw9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5gw9 GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Homo
sapiens) 		5 / 12 LEU A  85
ALA A 115
SER A 165
LEU A 162
LEU A  62
 None
 1.48A 1ya3B-5gw9A:
undetectable		 1ya3B-5gw9A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 5gw9 GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Homo
sapiens) 		4 / 4 LEU A  55
SER A 143
LEU A 153
LEU A  51
 None
 1.12A 1yajA-5gw9A:
undetectable		 1yajA-5gw9A:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 5gw9 GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Homo
sapiens) 		4 / 6 LEU A  36
TYR A  40
ILE A  96
ARG A 147
 None
 0.94A 2q8hA-5gw9A:
undetectable		 2q8hA-5gw9A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5gw9 GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Homo
sapiens) 		4 / 7 PRO A  58
LEU A  89
ALA A  92
PHE A 141
 None
 0.90A 2vcvA-5gw9A:
undetectable		 2vcvA-5gw9A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5gw9 GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Homo
sapiens) 		4 / 7 PRO A  58
LEU A  89
ALA A  92
PHE A 141
 None
 0.94A 2vcvG-5gw9A:
2.4		 2vcvG-5gw9A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5gw9 GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Homo
sapiens) 		4 / 7 PRO A  58
LEU A  89
ALA A  92
PHE A 141
 None
 0.84A 2vcvL-5gw9A:
undetectable		 2vcvL-5gw9A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 5gw9 GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Homo
sapiens) 		4 / 6 GLN A 146
GLY A 150
ARG A 148
LEU A  36
 None
 1.06A 3bjwE-5gw9A:
undetectable		 3bjwE-5gw9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 5gw9 GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Homo
sapiens) 		5 / 12 GLY A 151
ALA A  31
LEU A  89
THR A 106
LEU A 107
 None
 1.00A 3p2kA-5gw9A:
undetectable		 3p2kA-5gw9A:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5gw9 GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Homo
sapiens) 		4 / 6 LEU A  50
GLU A  46
VAL A 152
ALA A 149
 None
 1.10A 4nkvC-5gw9A:
undetectable		 4nkvC-5gw9A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 5gw9 GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Homo
sapiens) 		5 / 12 LEU A  51
ILE A  96
LEU A  90
PHE A 141
LEU A 107
 None
 1.25A 5tiwA-5gw9A:
undetectable		 5tiwA-5gw9A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 5gw9 GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Homo
sapiens) 		5 / 12 LEU A  32
LEU A 107
SER A 143
LEU A  36
LEU A  48
 None
 1.04A 6ew0B-5gw9A:
undetectable		 6ew0B-5gw9A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 5gw9 GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Homo
sapiens) 		5 / 12 LEU A  32
LEU A 107
SER A 143
LEU A  36
LEU A  48
 None
 1.04A 6ew0D-5gw9A:
undetectable		 6ew0D-5gw9A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 5gw9 GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Homo
sapiens) 		5 / 12 LEU A  32
LEU A 107
SER A 143
LEU A  36
LEU A  48
 None
 1.04A 6ew0H-5gw9A:
undetectable		 6ew0H-5gw9A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 5gw9 GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Homo
sapiens) 		5 / 12 LEU A  32
LEU A 107
SER A 143
LEU A  36
LEU A  48
 None
 1.04A 6ew0I-5gw9A:
undetectable		 6ew0I-5gw9A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA605_0
(SERUM ALBUMIN)		 5gw9 GRANULOCYTE
COLONY-STIMULATING
FACTOR
(Homo
sapiens) 		4 / 8 GLY A  52
GLY A 150
LEU A 153
GLU A  47
 None
 0.84A 6mdqA-5gw9A:
undetectable		 6mdqA-5gw9A:
19.14