SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gwo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		4 / 6 LEU A 109
LEU A 207
LEU A  97
LEU A 100
 None
 0.78A 1errA-5gwoA:
undetectable		 1errA-5gwoA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB8_0
(GRAMICIDIN D)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		3 / 3 VAL A 291
VAL A 215
TRP A 160
 None
 1.00A 1w5uA-5gwoA:
undetectable
1w5uB-5gwoA:
undetectable		 1w5uA-5gwoA:
4.29
1w5uB-5gwoA:
4.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		5 / 12 LEU A 268
LEU A 279
GLY A 275
CYH A 129
ALA A 203
 None
 1.15A 2bm9A-5gwoA:
undetectable		 2bm9A-5gwoA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		5 / 12 LEU A 268
LEU A 279
GLY A 275
CYH A 129
ALA A 203
 None
 1.12A 2bm9B-5gwoA:
undetectable		 2bm9B-5gwoA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		5 / 12 LEU A 268
LEU A 279
GLY A 275
CYH A 129
ALA A 203
 None
 1.11A 2bm9C-5gwoA:
undetectable		 2bm9C-5gwoA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		5 / 12 LEU A 268
LEU A 279
GLY A 275
CYH A 129
ALA A 203
 None
 1.13A 2bm9D-5gwoA:
undetectable		 2bm9D-5gwoA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		5 / 12 LEU A 268
LEU A 279
GLY A 275
CYH A 129
ALA A 203
 None
 1.08A 2br4C-5gwoA:
undetectable		 2br4C-5gwoA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		5 / 11 LEU A 234
ARG A 227
VAL A 208
ALA A 206
LEU A 301
 None
 1.19A 2bxgA-5gwoA:
2.0		 2bxgA-5gwoA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		5 / 10 ALA A  84
LEU A  91
SER A 138
LEU A 141
ARG A 108
 None
 1.38A 2ceoB-5gwoA:
undetectable		 2ceoB-5gwoA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		4 / 5 VAL A 194
THR A 195
VAL A 199
GLY A 200
 None
 0.90A 2p2fA-5gwoA:
undetectable		 2p2fA-5gwoA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_B_ACTB653_0
(ACETYL-COENZYME A
SYNTHETASE)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		4 / 4 VAL A 194
THR A 195
VAL A 199
GLY A 200
 None
 0.94A 2p2fB-5gwoA:
undetectable		 2p2fB-5gwoA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ACTA908_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		4 / 4 MET A 270
SER A 273
LEU A 268
VAL A 283
 None
 1.45A 3vlnA-5gwoA:
0.4		 3vlnA-5gwoA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		4 / 5 ASP A 276
VAL A 199
GLY A 121
TYR A 278
 None
 1.10A 3w9tA-5gwoA:
undetectable		 3w9tA-5gwoA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		4 / 5 ASP A 276
VAL A 199
GLY A 121
TYR A 278
 None
 1.10A 3w9tB-5gwoA:
undetectable		 3w9tB-5gwoA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		4 / 5 ASP A 276
VAL A 199
GLY A 121
TYR A 278
 None
 1.09A 3w9tC-5gwoA:
undetectable		 3w9tC-5gwoA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		4 / 5 ASP A 276
VAL A 199
GLY A 121
TYR A 278
 None
 1.09A 3w9tD-5gwoA:
undetectable		 3w9tD-5gwoA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		4 / 5 ASP A 276
VAL A 199
GLY A 121
TYR A 278
 None
 1.09A 3w9tE-5gwoA:
undetectable		 3w9tE-5gwoA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		4 / 5 ASP A 276
VAL A 199
GLY A 121
TYR A 278
 None
 1.10A 3w9tF-5gwoA:
undetectable		 3w9tF-5gwoA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		4 / 5 ASP A 276
VAL A 199
GLY A 121
TYR A 278
 None
 1.09A 3w9tG-5gwoA:
undetectable		 3w9tG-5gwoA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		5 / 12 ASN A 369
ASP A 118
LEU A 268
ASP A 276
GLY A 121
 None
MG  A 403 ( 2.4A)
None
None
None
 1.46A 4djeA-5gwoA:
undetectable		 4djeA-5gwoA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		5 / 12 PHE A 164
ILE A 133
ALA A 216
LEU A 113
LEU A 141
 None
 1.27A 4qztC-5gwoA:
1.0		 4qztC-5gwoA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		5 / 12 PHE A 164
ILE A 133
ALA A 216
LEU A 113
LEU A 141
 None
 1.25A 4qzuA-5gwoA:
1.2		 4qzuA-5gwoA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT7_A_TOPA302_1
(RV2671)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		5 / 11 ASN A 217
SER A 271
GLU A 245
GLU A 288
THR A 202
 None
 1.28A 4xt7A-5gwoA:
undetectable		 4xt7A-5gwoA:
25.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50
(Oryza
sativa) 		5 / 12 LEU A 141
LEU A 137
LEU A  90
PRO A 287
ALA A 216
 None
 1.17A 5og9B-5gwoA:
undetectable		 5og9B-5gwoA:
20.33