SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gwp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SQN_A_NDRA1001_0 (PROGESTERONE RECEPTOR)	5gwp	ABA RECEPTOR RCAR3 (Oryza sativa)	5 / 12	LEU C 179 LEU C 178 ASN C 182 LEU C 132 TYR C 135	None A8S C 301 (-4.2A) A8S C 301 (-3.7A) None A8S C 301 ( 4.8A)	1.39A	1sqnA-5gwpC: undetectable	1sqnA-5gwpC: 19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q72_A_IXXA802_1 (TRANSPORTER)	5gwp	ABA RECEPTOR RCAR3 (Oryza sativa)	4 / 6	ILE C 138 SER C 136 ARG C 110 ILE C 90	None	1.07A	2q72A-5gwpC: undetectable	2q72A-5gwpC: 15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W8Y_B_NDRB1000_0 (PROGESTERONE RECEPTOR)	5gwp	ABA RECEPTOR RCAR3 (Oryza sativa)	5 / 12	LEU C 179 LEU C 178 ASN C 182 LEU C 132 TYR C 135	None A8S C 301 (-4.2A) A8S C 301 (-3.7A) None A8S C 301 ( 4.8A)	1.40A	2w8yB-5gwpC: undetectable	2w8yB-5gwpC: 21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D90_A_NOGA1001_1 (PROGESTERONE RECEPTOR)	5gwp	ABA RECEPTOR RCAR3 (Oryza sativa)	5 / 12	LEU C 179 LEU C 178 ASN C 182 LEU C 132 TYR C 135	None A8S C 301 (-4.2A) A8S C 301 (-3.7A) None A8S C 301 ( 4.8A)	1.39A	3d90A-5gwpC: undetectable	3d90A-5gwpC: 21.63

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1SQN_A_NDRA1001_0","PROGESTERONE RECEPTOR","5gwp","ABA RECEPTOR RCAR3","Oryza sativa",5,"LEU C 179;LEU C 178;ASN C 182;LEU C 132;TYR C 135","None;A8S C 301 (-4.2A);A8S C 301 (-3.7A);None;A8S C 301 ( 4.8A)","1.39A","1sqnA-5gwpC:undetectable","1sqnA-5gwpC:19.85"],["2Q72_A_IXXA802_1","TRANSPORTER","5gwp","ABA RECEPTOR RCAR3","Oryza sativa",4,"ILE C 138;SER C 136;ARG C 110;ILE C  90","None","1.07A","2q72A-5gwpC:undetectable","2q72A-5gwpC:15.84"],["2W8Y_B_NDRB1000_0","PROGESTERONE RECEPTOR","5gwp","ABA RECEPTOR RCAR3","Oryza sativa",5,"LEU C 179;LEU C 178;ASN C 182;LEU C 132;TYR C 135","None;A8S C 301 (-4.2A);A8S C 301 (-3.7A);None;A8S C 301 ( 4.8A)","1.40A","2w8yB-5gwpC:undetectable","2w8yB-5gwpC:21.63"],["3D90_A_NOGA1001_1","PROGESTERONE RECEPTOR","5gwp","ABA RECEPTOR RCAR3","Oryza sativa",5,"LEU C 179;LEU C 178;ASN C 182;LEU C 132;TYR C 135","None;A8S C 301 (-4.2A);A8S C 301 (-3.7A);None;A8S C 301 ( 4.8A)","1.39A","3d90A-5gwpC:undetectable","3d90A-5gwpC:21.63"]]