SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gx8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 7 LEU A 218
ASP A 282
THR A 281
TRP A 163
None
1.09A 1v55C-5gx8A:
undetectable
1v55N-5gx8A:
2.5
1v55P-5gx8A:
3.1
1v55C-5gx8A:
20.67
1v55N-5gx8A:
20.36
1v55P-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A7Q_A_CFBA328_2
(DEOXYCYTIDINE KINASE)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 4 ILE A 285
ASP A 427
LEU A 308
ARG A 322
None
EDO  A 602 ( 4.7A)
None
None
1.38A 2a7qA-5gx8A:
undetectable
2a7qA-5gx8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGZ_D_COCD401_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 6 TRP A 329
TYR A 399
TYR A 344
ILE A  86
None
1.32A 2pgzD-5gx8A:
undetectable
2pgzE-5gx8A:
undetectable
2pgzD-5gx8A:
20.48
2pgzE-5gx8A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 7 TRP A 329
TYR A 399
TYR A 344
ILE A  86
None
1.29A 2ph9A-5gx8A:
undetectable
2ph9B-5gx8A:
undetectable
2ph9A-5gx8A:
20.48
2ph9B-5gx8A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 5 PHE A 201
PHE A 202
LEU A 273
PHE A 302
None
1.30A 2y69C-5gx8A:
3.0
2y69J-5gx8A:
undetectable
2y69C-5gx8A:
20.67
2y69J-5gx8A:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 LEU A 218
ASP A 282
THR A 281
TRP A 163
None
1.12A 2y69C-5gx8A:
3.0
2y69N-5gx8A:
4.2
2y69P-5gx8A:
3.0
2y69C-5gx8A:
20.67
2y69N-5gx8A:
20.36
2y69P-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 5 PHE A 201
PHE A 202
LEU A 273
PHE A 302
None
1.31A 2y69P-5gx8A:
3.0
2y69W-5gx8A:
undetectable
2y69P-5gx8A:
20.67
2y69W-5gx8A:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 ASP A 282
THR A 281
TRP A 163
LEU A 218
None
1.07A 3ablA-5gx8A:
3.5
3ablC-5gx8A:
3.0
3ablP-5gx8A:
undetectable
3ablA-5gx8A:
20.36
3ablC-5gx8A:
20.67
3ablP-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 LEU A 218
ASP A 282
THR A 281
TRP A 163
None
1.10A 3ablC-5gx8A:
3.1
3ablN-5gx8A:
2.4
3ablP-5gx8A:
undetectable
3ablC-5gx8A:
20.67
3ablN-5gx8A:
20.36
3ablP-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 ASP A 282
THR A 281
TRP A 163
LEU A 218
None
1.07A 3abmA-5gx8A:
3.0
3abmC-5gx8A:
3.1
3abmP-5gx8A:
undetectable
3abmA-5gx8A:
20.36
3abmC-5gx8A:
20.67
3abmP-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 5 PHE A 201
PHE A 202
LEU A 273
PHE A 302
None
1.34A 3abmP-5gx8A:
undetectable
3abmW-5gx8A:
undetectable
3abmP-5gx8A:
20.67
3abmW-5gx8A:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 LEU A 218
ASP A 282
THR A 281
TRP A 163
None
1.06A 3asnC-5gx8A:
undetectable
3asnN-5gx8A:
3.0
3asnP-5gx8A:
2.7
3asnC-5gx8A:
20.67
3asnN-5gx8A:
20.36
3asnP-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 ASP A 282
THR A 281
TRP A 163
LEU A 218
None
1.08A 3asoA-5gx8A:
2.4
3asoC-5gx8A:
undetectable
3asoP-5gx8A:
3.0
3asoA-5gx8A:
20.36
3asoC-5gx8A:
20.67
3asoP-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 LEU A 218
ASP A 282
THR A 281
TRP A 163
None
1.07A 3asoC-5gx8A:
undetectable
3asoN-5gx8A:
2.5
3asoP-5gx8A:
3.0
3asoC-5gx8A:
20.67
3asoN-5gx8A:
20.36
3asoP-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
3 / 3 PHE A 404
TYR A 148
LEU A 401
None
0.66A 3keeB-5gx8A:
undetectable
3keeB-5gx8A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
3 / 3 ASN A 275
ASN A 193
GLU A 198
None
CA  A 601 (-3.1A)
CA  A 601 (-2.2A)
0.88A 3kpdC-5gx8A:
undetectable
3kpdC-5gx8A:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
3 / 3 PHE A 404
TYR A 148
LEU A 401
None
0.71A 3sueB-5gx8A:
undetectable
3sueB-5gx8A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
5 / 11 ILE A 245
PHE A 262
ILE A 261
ALA A 463
VAL A 216
None
1.04A 3tmzA-5gx8A:
undetectable
3tmzA-5gx8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 ASP A 282
THR A 281
TRP A 163
LEU A 218
None
1.08A 3wg7A-5gx8A:
3.6
3wg7C-5gx8A:
3.0
3wg7P-5gx8A:
2.7
3wg7A-5gx8A:
20.36
3wg7C-5gx8A:
20.67
3wg7P-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 LEU A 218
ASP A 282
THR A 281
TRP A 163
None
1.10A 3wg7C-5gx8A:
3.1
3wg7N-5gx8A:
3.6
3wg7P-5gx8A:
2.8
3wg7C-5gx8A:
20.67
3wg7N-5gx8A:
20.36
3wg7P-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 ASP A 282
THR A 281
TRP A 163
LEU A 218
None
1.10A 3x2qA-5gx8A:
3.2
3x2qC-5gx8A:
3.1
3x2qP-5gx8A:
3.0
3x2qA-5gx8A:
20.36
3x2qC-5gx8A:
20.67
3x2qP-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 LEU A 218
ASP A 282
THR A 281
TRP A 163
None
1.13A 3x2qC-5gx8A:
3.1
3x2qN-5gx8A:
2.7
3x2qP-5gx8A:
3.1
3x2qC-5gx8A:
20.67
3x2qN-5gx8A:
20.36
3x2qP-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7A_A_MXDA1002_1
(ANDROGEN RECEPTOR)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
3 / 3 GLU A 198
TRP A 163
LYS A 195
CA  A 601 (-2.2A)
None
None
1.25A 4k7aA-5gx8A:
undetectable
4k7aA-5gx8A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 7 ARG A 264
ASP A 258
ILE A 261
TYR A 252
SO4  A 605 (-2.8A)
None
None
None
0.93A 5a06B-5gx8A:
undetectable
5a06B-5gx8A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 ASP A 282
THR A 281
TRP A 163
LEU A 218
None
1.10A 5b1aA-5gx8A:
3.5
5b1aC-5gx8A:
3.0
5b1aP-5gx8A:
3.0
5b1aA-5gx8A:
20.36
5b1aC-5gx8A:
20.67
5b1aP-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 ASP A 282
THR A 281
TRP A 163
LEU A 218
None
1.11A 5b1bA-5gx8A:
3.3
5b1bC-5gx8A:
undetectable
5b1bP-5gx8A:
undetectable
5b1bA-5gx8A:
20.36
5b1bC-5gx8A:
20.67
5b1bP-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 ASP A 282
THR A 281
TRP A 163
LEU A 218
None
1.09A 5b3sA-5gx8A:
2.4
5b3sC-5gx8A:
3.1
5b3sP-5gx8A:
undetectable
5b3sA-5gx8A:
20.36
5b3sC-5gx8A:
20.67
5b3sP-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 6 TYR A  74
GLY A 327
SER A  92
LEU A  95
None
1.23A 5bphA-5gx8A:
undetectable
5bphA-5gx8A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 4 TYR A  74
GLY A 327
SER A  92
LEU A  95
None
1.25A 5bphC-5gx8A:
undetectable
5bphC-5gx8A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 6 TYR A  74
GLY A 327
SER A  92
LEU A  95
None
1.24A 5bphD-5gx8A:
undetectable
5bphD-5gx8A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 ASP A 282
THR A 281
TRP A 163
LEU A 218
None
1.11A 5xdqA-5gx8A:
undetectable
5xdqC-5gx8A:
3.1
5xdqP-5gx8A:
3.1
5xdqA-5gx8A:
20.36
5xdqC-5gx8A:
20.67
5xdqP-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 LEU A 218
ASP A 282
THR A 281
TRP A 163
None
1.08A 5xdqC-5gx8A:
3.1
5xdqN-5gx8A:
3.4
5xdqP-5gx8A:
3.1
5xdqC-5gx8A:
20.67
5xdqN-5gx8A:
20.36
5xdqP-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 LEU A 218
ASP A 282
THR A 281
TRP A 163
None
1.11A 5xdxC-5gx8A:
2.9
5xdxN-5gx8A:
3.1
5xdxP-5gx8A:
3.0
5xdxC-5gx8A:
20.45
5xdxN-5gx8A:
20.36
5xdxP-5gx8A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 ASP A 282
THR A 281
TRP A 163
LEU A 218
None
1.09A 5z84A-5gx8A:
undetectable
5z84C-5gx8A:
3.0
5z84P-5gx8A:
3.0
5z84A-5gx8A:
20.36
5z84C-5gx8A:
20.67
5z84P-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 7 LEU A 218
ASP A 282
THR A 281
TRP A 163
None
1.10A 5z84C-5gx8A:
3.0
5z84N-5gx8A:
3.4
5z84P-5gx8A:
3.1
5z84C-5gx8A:
20.67
5z84N-5gx8A:
20.36
5z84P-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 ASP A 282
THR A 281
TRP A 163
LEU A 218
None
1.11A 5z85A-5gx8A:
3.4
5z85C-5gx8A:
3.0
5z85P-5gx8A:
3.0
5z85A-5gx8A:
20.36
5z85C-5gx8A:
20.67
5z85P-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 7 LEU A 218
ASP A 282
THR A 281
TRP A 163
None
1.08A 5z85C-5gx8A:
2.9
5z85N-5gx8A:
3.6
5z85P-5gx8A:
3.1
5z85C-5gx8A:
20.67
5z85N-5gx8A:
20.36
5z85P-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 ASP A 282
THR A 281
TRP A 163
LEU A 218
None
1.10A 5z86A-5gx8A:
3.5
5z86C-5gx8A:
3.1
5z86P-5gx8A:
3.0
5z86A-5gx8A:
20.36
5z86C-5gx8A:
20.67
5z86P-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 LEU A 218
ASP A 282
THR A 281
TRP A 163
None
1.11A 5z86C-5gx8A:
3.1
5z86N-5gx8A:
3.1
5z86P-5gx8A:
3.0
5z86C-5gx8A:
20.67
5z86N-5gx8A:
20.36
5z86P-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 ASP A 282
THR A 281
TRP A 163
LEU A 218
None
1.11A 5zcoA-5gx8A:
3.5
5zcoC-5gx8A:
3.0
5zcoP-5gx8A:
2.8
5zcoA-5gx8A:
20.36
5zcoC-5gx8A:
20.67
5zcoP-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 LEU A 218
ASP A 282
THR A 281
TRP A 163
None
1.10A 5zcoC-5gx8A:
3.0
5zcoN-5gx8A:
3.4
5zcoP-5gx8A:
2.8
5zcoC-5gx8A:
20.67
5zcoN-5gx8A:
20.36
5zcoP-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 ASP A 282
THR A 281
TRP A 163
LEU A 218
None
1.13A 5zcpA-5gx8A:
3.2
5zcpC-5gx8A:
3.1
5zcpP-5gx8A:
3.0
5zcpA-5gx8A:
20.36
5zcpC-5gx8A:
20.67
5zcpP-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 LEU A 218
ASP A 282
THR A 281
TRP A 163
None
1.10A 5zcpC-5gx8A:
3.1
5zcpN-5gx8A:
3.2
5zcpP-5gx8A:
3.0
5zcpC-5gx8A:
20.67
5zcpN-5gx8A:
20.36
5zcpP-5gx8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis)
4 / 8 ASP A 282
THR A 281
TRP A 163
LEU A 218
None
1.09A 5zcqA-5gx8A:
2.9
5zcqC-5gx8A:
3.0
5zcqP-5gx8A:
3.1
5zcqA-5gx8A:
20.36
5zcqC-5gx8A:
20.67
5zcqP-5gx8A:
20.67