SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gxd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 5 GLY A 166
GLN A 200
VAL A 119
SER A 164
 None
 1.16A 1p6kB-5gxdA:
undetectable		 1p6kB-5gxdA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		5 / 7 THR A 243
GLU A 147
THR A 242
SER A 506
VAL A 525
 None
GOL  A 705 (-2.8A)
None
None
None
 1.29A 1tv8A-5gxdA:
undetectable		 1tv8A-5gxdA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 7 GLU A 147
THR A 242
SER A 506
VAL A 525
 GOL  A 705 (-2.8A)
None
None
None
 1.18A 1tv8B-5gxdA:
undetectable		 1tv8B-5gxdA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		5 / 11 LEU A 505
ILE A 566
PHE A 143
ASP A 281
GLY A 283
 None
None
None
COA  A 703 ( 4.4A)
None
 1.25A 1zz1A-5gxdA:
2.5		 1zz1A-5gxdA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 5 GLY A 166
GLN A 200
VAL A 119
SER A 164
 None
 1.15A 1zzuB-5gxdA:
undetectable		 1zzuB-5gxdA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		3 / 3 GLY A 534
GLU A 366
ASP A 530
 None
 0.67A 2b25B-5gxdA:
undetectable		 2b25B-5gxdA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		5 / 8 THR A 243
GLU A 147
THR A 242
SER A 506
VAL A 525
 None
GOL  A 705 (-2.8A)
None
None
None
 1.23A 2fb2A-5gxdA:
undetectable		 2fb2A-5gxdA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 7 GLU A 147
THR A 242
SER A 506
VAL A 525
 GOL  A 705 (-2.8A)
None
None
None
 1.20A 2fb2B-5gxdA:
undetectable		 2fb2B-5gxdA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		5 / 12 GLY A 287
THR A 391
ALA A 279
THR A 332
ALA A 333
 None
AMP  A 701 (-3.6A)
None
None
COA  A 703 ( 3.8A)
 1.09A 2gluA-5gxdA:
3.0		 2gluA-5gxdA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_D_SC2D1290_1
(FICOLIN-2)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 5 GLY A 394
TRP A 395
ARG A 251
LEU A 260
 None
 1.23A 2j2pD-5gxdA:
undetectable
2j2pF-5gxdA:
undetectable		 2j2pD-5gxdA:
16.18
2j2pF-5gxdA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_B_SAMB202_0
(UPF0066 PROTEIN
AF_0241)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		5 / 12 TYR A 238
GLY A 248
LEU A 455
ASP A 154
LEU A 113
 None
 1.25A 2nv4B-5gxdA:
undetectable		 2nv4B-5gxdA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 8 GLY A 365
GLN A 390
THR A 391
ARG A 504
 AMP  A 701 ( 3.3A)
AMP  A 701 (-4.3A)
AMP  A 701 (-3.6A)
AMP  A 701 ( 3.9A)
 0.31A 2wd9B-5gxdA:
41.6		 2wd9B-5gxdA:
26.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_C_IBPC1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		5 / 10 THR A 239
GLY A 365
GLN A 390
THR A 391
ARG A 504
 AMP  A 701 (-4.7A)
AMP  A 701 ( 3.3A)
AMP  A 701 (-4.3A)
AMP  A 701 (-3.6A)
AMP  A 701 ( 3.9A)
 0.43A 2wd9C-5gxdA:
41.6		 2wd9C-5gxdA:
26.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1467_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 5 ARG A 320
ASP A  75
ILE A 303
GLU A 324
 None
 1.39A 2xrzA-5gxdA:
2.9
2xrzB-5gxdA:
3.0		 2xrzA-5gxdA:
22.57
2xrzB-5gxdA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 6 TYR A 627
LEU A 574
VAL A 500
ASP A 530
 None
 1.18A 2zawA-5gxdA:
undetectable		 2zawA-5gxdA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 4 THR A 507
VAL A 528
GLY A 592
THR A 593
 None
 0.94A 3cflA-5gxdA:
undetectable		 3cflA-5gxdA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		5 / 9 GLY A 436
ASP A 483
ILE A 482
VAL A 425
VAL A 433
 None
 1.48A 3fhjD-5gxdA:
undetectable		 3fhjD-5gxdA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		5 / 9 GLY A 436
ASP A 483
ILE A 482
VAL A 425
VAL A 433
 None
 1.48A 3fhjF-5gxdA:
undetectable		 3fhjF-5gxdA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_E_TOPE200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		5 / 10 ALA A 216
LEU A 194
LEU A  97
ILE A 106
LEU A 132
 None
 1.03A 3fl9E-5gxdA:
undetectable		 3fl9E-5gxdA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 6 TYR A 627
LEU A 574
VAL A 500
ASP A 530
 None
 1.08A 3fwgA-5gxdA:
undetectable		 3fwgA-5gxdA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		5 / 12 ALA A 524
PHE A 540
ASN A 596
ILE A 597
LEU A 622
 None
 1.05A 3rukA-5gxdA:
undetectable		 3rukA-5gxdA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		5 / 12 ALA A 524
ASN A 596
ILE A 597
LEU A 622
GLY A 592
 None
 0.96A 3rukB-5gxdA:
undetectable		 3rukB-5gxdA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		5 / 11 ALA A 524
PHE A 540
ASN A 596
ILE A 597
GLY A 592
 None
 1.03A 3rukD-5gxdA:
undetectable		 3rukD-5gxdA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 6 TYR A 627
LEU A 574
VAL A 500
ASP A 530
 None
 1.08A 3wrjE-5gxdA:
undetectable		 3wrjE-5gxdA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 8 VAL A 361
TYR A 268
VAL A 382
ILE A 385
 None
 1.10A 4aftD-5gxdA:
undetectable
4aftE-5gxdA:
undetectable		 4aftD-5gxdA:
17.76
4aftE-5gxdA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_A_ADNA401_1
(APH(2'')-ID)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		5 / 10 ALA A 155
PRO A 190
ILE A 183
LEU A 179
ILE A 160
 None
 1.27A 4dtaA-5gxdA:
undetectable		 4dtaA-5gxdA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 6 TYR A 627
LEU A 574
VAL A 500
ASP A 530
 None
 1.06A 4ek1A-5gxdA:
undetectable		 4ek1A-5gxdA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 7 TYR A 290
LEU A 260
TRP A 389
TYR A 421
 None
 1.38A 4f8yC-5gxdA:
4.1
4f8yD-5gxdA:
4.0		 4f8yC-5gxdA:
16.61
4f8yD-5gxdA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 6 TYR A 627
LEU A 574
VAL A 500
ASP A 530
 None
 1.12A 4kkyX-5gxdA:
undetectable		 4kkyX-5gxdA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 6 TYR A 627
LEU A 574
VAL A 500
ASP A 530
 None
 1.10A 4l4cA-5gxdA:
undetectable		 4l4cA-5gxdA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 7 PRO A 449
ALA A  21
PHE A  17
TYR A   7
 None
 1.05A 4lb2A-5gxdA:
undetectable		 4lb2A-5gxdA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZU_B_Y70B505_1
(PROTEIN CEREBLON)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 7 TRP A  18
PHE A  46
THR A   6
TRP A 262
 None
 1.49A 4tzuB-5gxdA:
undetectable
4tzuC-5gxdA:
undetectable		 4tzuB-5gxdA:
10.72
4tzuC-5gxdA:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_B_BEZB1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 6 GLY A 394
THR A 393
SER A 289
VAL A 285
 None
None
None
AKR  A 702 ( 4.4A)
 0.99A 5ewuB-5gxdA:
2.4		 5ewuB-5gxdA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G08_A_Z80A1187_1
(FREQUENIN 2)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 6 ILE A 350
PHE A 349
PHE A 330
TRP A 277
 None
 1.19A 5g08A-5gxdA:
undetectable		 5g08A-5gxdA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 5 HIS A 136
HIS A 288
HIS A 256
ALA A 234
 None
 1.04A 5i3bB-5gxdA:
undetectable		 5i3bB-5gxdA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		3 / 3 LYS A 247
LYS A 464
SER A 465
 None
 1.14A 5odiA-5gxdA:
3.3		 5odiA-5gxdA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 5 ASN A  39
ASP A  38
ASP A  48
ASN A 231
 None
 1.48A 5vooA-5gxdA:
4.4		 5vooA-5gxdA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_Y_EF2Y501_1
(PROTEIN CEREBLON)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 7 THR A   6
TRP A 262
TRP A  18
PHE A  46
 None
 1.47A 5yizG-5gxdA:
undetectable
5yizY-5gxdA:
undetectable		 5yizG-5gxdA:
9.05
5yizY-5gxdA:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_Y_EF2Y501_1
(PROTEIN CEREBLON)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 7 THR A   6
TRP A 262
TRP A  18
PHE A  46
 None
 1.49A 5yj0G-5gxdA:
undetectable
5yj0Y-5gxdA:
undetectable		 5yj0G-5gxdA:
9.05
5yj0Y-5gxdA:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_K_6ELK501_0
(PROTEIN CEREBLON)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 7 TRP A  18
PHE A  46
THR A   6
TRP A 262
 None
 1.41A 5yj1k-5gxdA:
undetectable
5yj1t-5gxdA:
undetectable		 5yj1k-5gxdA:
10.67
5yj1t-5gxdA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_Y_6ELY501_0
(PROTEIN CEREBLON)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 7 THR A   6
TRP A 262
TRP A  18
PHE A  46
 None
 1.45A 5yj1G-5gxdA:
undetectable
5yj1Y-5gxdA:
undetectable		 5yj1G-5gxdA:
10.67
5yj1Y-5gxdA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		3 / 3 LYS A 341
LEU A 363
ASP A 369
 None
 0.67A 5zv2A-5gxdA:
undetectable		 5zv2A-5gxdA:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_2
(-)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		5 / 9 THR A 451
GLY A 450
GLY A 255
TYR A 421
TRP A  10
 None
 1.35A 6gnfA-5gxdA:
undetectable		 6gnfA-5gxdA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE
(Dinoroseobacter
shibae) 		4 / 5 LEU A 237
TYR A 235
ILE A 303
GLY A 394
 None
 1.05A 6hd6A-5gxdA:
undetectable		 6hd6A-5gxdA:
9.49