SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gy2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 5gy2 FLAGELLIN
(Bacillus
subtilis) 		3 / 3 GLY C 207
GLU C  77
ASN C 211
 None
 0.63A 1zq9A-5gy2C:
undetectable		 1zq9A-5gy2C:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 5gy2 FLAGELLIN
(Bacillus
subtilis) 		5 / 9 LEU C 175
VAL C 172
GLY C 171
ASP C 193
ILE C 196
 None
 1.33A 2a1oB-5gy2C:
undetectable		 2a1oB-5gy2C:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5gy2 FLAGELLIN
(Bacillus
subtilis) 		5 / 12 VAL C 172
ILE C 196
VAL C 199
LEU C  80
LEU C  87
 None
 1.36A 4m11C-5gy2C:
undetectable		 4m11C-5gy2C:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_D_MXMD606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5gy2 FLAGELLIN
(Bacillus
subtilis) 		5 / 12 VAL C 172
ILE C 196
VAL C 199
LEU C  80
LEU C  87
 None
 1.35A 4m11D-5gy2C:
undetectable		 4m11D-5gy2C:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 5gy2 FLAGELLIN
(Bacillus
subtilis) 		4 / 8 ILE C 122
THR C  94
VAL C  95
GLU C  92
 None
 0.84A 6fbvC-5gy2C:
undetectable		 6fbvC-5gy2C:
9.75