SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gy3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 5gy3 GLUCANASE
(Klebsiella
pneumoniae) 		3 / 3 GLN A  55
TYR A  30
ARG A  29
 None
 0.88A 1gtbA-5gy3A:
3.1		 1gtbA-5gy3A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5gy3 GLUCANASE
(Klebsiella
pneumoniae) 		3 / 3 ASN A  65
TRP A  27
GLN A 125
 None
 1.23A 1xoqA-5gy3A:
undetectable		 1xoqA-5gy3A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA11_1
(CES1 PROTEIN)		 5gy3 GLUCANASE
(Klebsiella
pneumoniae) 		4 / 8 TRP A 326
LEU A 324
LEU A  61
PRO A 308
 None
 0.89A 1ya4A-5gy3A:
undetectable		 1ya4A-5gy3A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 5gy3 GLUCANASE
(Klebsiella
pneumoniae) 		4 / 8 TYR A 175
ASP A 110
TYR A 316
HIS A  51
 None
 1.32A 2bteA-5gy3A:
2.6		 2bteA-5gy3A:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_A_LEUA1301_0
(LEUCYL-TRNA
SYNTHETASE)		 5gy3 GLUCANASE
(Klebsiella
pneumoniae) 		4 / 7 TYR A 175
ASP A 110
TYR A 316
HIS A  51
 None
 1.29A 2bytA-5gy3A:
2.1		 2bytA-5gy3A:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_D_LEUD1601_0
(LEUCYL-TRNA
SYNTHETASE)		 5gy3 GLUCANASE
(Klebsiella
pneumoniae) 		4 / 7 TYR A 175
ASP A 110
TYR A 316
HIS A  51
 None
 1.29A 2bytD-5gy3A:
2.4		 2bytD-5gy3A:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 5gy3 GLUCANASE
(Klebsiella
pneumoniae) 		4 / 6 TRP A 326
LEU A 324
LEU A  61
PRO A 308
 None
 0.98A 2dqyC-5gy3A:
undetectable		 2dqyC-5gy3A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 5gy3 GLUCANASE
(Klebsiella
pneumoniae) 		4 / 8 TYR A 175
ASP A 110
TYR A 316
HIS A  51
 None
 1.36A 2v0gA-5gy3A:
undetectable		 2v0gA-5gy3A:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAU_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5gy3 GLUCANASE
(Klebsiella
pneumoniae) 		5 / 12 ALA A  26
LEU A  61
ALA A  64
ILE A  41
LEU A  74
 None
 1.03A 3dauA-5gy3A:
undetectable		 3dauA-5gy3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 5gy3 GLUCANASE
(Klebsiella
pneumoniae) 		3 / 3 TYR A 175
ASP A 112
HIS A  51
 None
 0.90A 3e23A-5gy3A:
undetectable		 3e23A-5gy3A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 5gy3 GLUCANASE
(Klebsiella
pneumoniae) 		6 / 9 LEU A 324
GLY A 292
ALA A 295
ASP A 298
ILE A 310
VAL A 325
 None
 1.35A 3u7sA-5gy3A:
undetectable		 3u7sA-5gy3A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5gy3 GLUCANASE
(Klebsiella
pneumoniae) 		5 / 12 ASP A 136
ILE A 138
ILE A 177
TYR A 247
MET A  59
 None
 1.26A 4a84A-5gy3A:
undetectable		 4a84A-5gy3A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5gy3 GLUCANASE
(Klebsiella
pneumoniae) 		4 / 6 SER A 135
ASP A 136
THR A 188
PHE A 184
 None
 0.95A 4acbC-5gy3A:
undetectable		 4acbC-5gy3A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ARC_A_LEUA1001_0
(LEUCINE--TRNA LIGASE)		 5gy3 GLUCANASE
(Klebsiella
pneumoniae) 		4 / 7 TYR A 175
ASP A 110
TYR A 316
HIS A  51
 None
 1.19A 4arcA-5gy3A:
undetectable		 4arcA-5gy3A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 5gy3 GLUCANASE
(Klebsiella
pneumoniae) 		5 / 12 LEU A 321
LEU A 324
LEU A 327
ALA A 328
ALA A 180
 None
 0.88A 4fn9A-5gy3A:
undetectable		 4fn9A-5gy3A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)		 5gy3 GLUCANASE
(Klebsiella
pneumoniae) 		3 / 3 ARG A  40
ASP A  38
TRP A  77
 None
 1.10A 4xdqA-5gy3A:
undetectable		 4xdqA-5gy3A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 5gy3 GLUCANASE
(Klebsiella
pneumoniae) 		3 / 3 ASP A 217
GLU A  53
SER A 212
 None
 0.73A 5bw4B-5gy3A:
undetectable		 5bw4B-5gy3A:
23.19