SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gyd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 5gyd MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Saccharomyces
cerevisiae) 		5 / 11 LEU A  43
ILE A 135
ARG A  41
LEU A 244
PHE A 248
 None
 1.37A 2bxmA-5gydA:
undetectable		 2bxmA-5gydA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5gyd MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Saccharomyces
cerevisiae) 		4 / 8 GLN A 174
ASP A 118
SER A 172
SER A 115
 None
 1.16A 2xz5C-5gydA:
undetectable
2xz5D-5gydA:
undetectable		 2xz5C-5gydA:
23.83
2xz5D-5gydA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5gyd MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Saccharomyces
cerevisiae) 		4 / 7 LYS A 254
ASP A 250
ILE A 247
TYR A  27
 None
 1.34A 5a06B-5gydA:
undetectable		 5a06B-5gydA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_2
(CYCLIN-DEPENDENT
KINASE 6)		 5gyd MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 254
GLN A  29
ASN A  30
 None
 1.06A 5l2tA-5gydA:
undetectable		 5l2tA-5gydA:
22.39