SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gyl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FAP_A_RAPA108_2
(FK506-BINDING
PROTEIN
FRAP)		 5gyl LEGUMIN-LIKE PROTEIN
(Cicer
arietinum) 		4 / 8 SER A 431
ARG A 429
PHE A 430
TYR A 384
 None
 1.09A 1fapB-5gylA:
undetectable		 1fapB-5gylA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_B_SALB503_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 5gyl LEGUMIN-LIKE PROTEIN
(Cicer
arietinum) 		5 / 10 ALA A 423
LEU A 392
PHE A 371
PHE A 483
LEU A 383
 None
 1.23A 1y7iB-5gylA:
undetectable		 1y7iB-5gylA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 5gyl LEGUMIN-LIKE PROTEIN
(Cicer
arietinum) 		4 / 6 ARG A 179
THR A 167
ALA A  87
PRO A  57
 None
 1.32A 2ql8A-5gylA:
undetectable
2ql8B-5gylA:
undetectable		 2ql8A-5gylA:
15.27
2ql8B-5gylA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_A_1GNA998_1
(GALECTIN-7)		 5gyl LEGUMIN-LIKE PROTEIN
(Cicer
arietinum) 		4 / 6 HIS A 187
ARG A  81
ASN A 186
GLU A 237
 None
 1.38A 3galA-5gylA:
undetectable		 3galA-5gylA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_B_1GNB999_1
(GALECTIN-7)		 5gyl LEGUMIN-LIKE PROTEIN
(Cicer
arietinum) 		4 / 6 HIS A 187
ARG A  81
ASN A 186
GLU A 237
 None
 1.39A 3galB-5gylA:
undetectable		 3galB-5gylA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 5gyl LEGUMIN-LIKE PROTEIN
(Cicer
arietinum) 		4 / 6 LEU A 484
SER A 482
PHE A 483
ILE A 342
 None
 0.94A 3ko0B-5gylA:
undetectable		 3ko0B-5gylA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 5gyl LEGUMIN-LIKE PROTEIN
(Cicer
arietinum) 		4 / 6 LEU A 484
SER A 482
PHE A 483
ILE A 342
 None
 0.88A 3ko0S-5gylA:
undetectable		 3ko0S-5gylA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U88_A_CHDA611_0
(MENIN)		 5gyl LEGUMIN-LIKE PROTEIN
(Cicer
arietinum) 		3 / 3 SER A 211
PHE A 213
LYS A 214
 None
 0.90A 3u88A-5gylA:
undetectable		 3u88A-5gylA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 5gyl LEGUMIN-LIKE PROTEIN
(Cicer
arietinum) 		3 / 3 ASP A 439
ARG A 354
ASP A 166
 None
 0.82A 4fp9C-5gylA:
undetectable		 4fp9C-5gylA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 5gyl LEGUMIN-LIKE PROTEIN
(Cicer
arietinum) 		3 / 3 ASP A 439
ARG A 354
ASP A 166
 None
 0.83A 4fp9F-5gylA:
undetectable		 4fp9F-5gylA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 5gyl LEGUMIN-LIKE PROTEIN
(Cicer
arietinum) 		3 / 3 TYR A 182
GLN A  89
TRP A 150
 None
 1.11A 4kn2C-5gylA:
undetectable		 4kn2C-5gylA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 5gyl LEGUMIN-LIKE PROTEIN
(Cicer
arietinum) 		5 / 12 GLY A  96
ASN A  97
ILE A 160
PHE A  92
LEU A 386
 None
 1.30A 4kotA-5gylA:
undetectable		 4kotA-5gylA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)		 5gyl LEGUMIN-LIKE PROTEIN
(Cicer
arietinum) 		5 / 12 GLY A  96
ASN A  97
ILE A 160
PHE A  92
LEU A 386
 None
 1.35A 4kovA-5gylA:
undetectable		 4kovA-5gylA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 5gyl LEGUMIN-LIKE PROTEIN
(Cicer
arietinum) 		5 / 12 ASN A 376
PRO A 373
GLN A 393
ALA A 422
ILE A 421
 None
 1.26A 4uroC-5gylA:
undetectable		 4uroC-5gylA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)		 5gyl LEGUMIN-LIKE PROTEIN
(Cicer
arietinum) 		3 / 3 MET A 467
GLU A 471
LEU A 475
 None
 0.72A 4v2oB-5gylA:
undetectable		 4v2oB-5gylA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 5gyl LEGUMIN-LIKE PROTEIN
(Cicer
arietinum) 		5 / 12 SER A 431
GLY A 327
ASP A 349
VAL A 345
THR A 346
 None
 1.13A 5kpcB-5gylA:
undetectable		 5kpcB-5gylA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 5gyl LEGUMIN-LIKE PROTEIN
(Cicer
arietinum) 		4 / 6 SER A 425
SER A 364
ALA A 385
ALA A 390
 None
 0.91A 6bocA-5gylA:
undetectable
6bocB-5gylA:
undetectable
6bocC-5gylA:
undetectable
6bocD-5gylA:
undetectable		 6bocA-5gylA:
3.97
6bocB-5gylA:
3.97
6bocC-5gylA:
3.97
6bocD-5gylA:
3.97