SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gyr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_A_CCSA417_0
(ESTROGEN RECEPTOR)		 5gyr CYTOCHROME C'
(Allochromatium
vinosum) 		3 / 3 GLU A   6
LYS A  70
VAL A  69
 None
 0.98A 1l2iA-5gyrA:
undetectable		 1l2iA-5gyrA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_E_SAME1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 5gyr CYTOCHROME C'
(Allochromatium
vinosum) 		5 / 12 GLY A  24
GLY A  20
ASN A  29
ALA A  28
GLU A  17
 None
 1.26A 2vdvE-5gyrA:
undetectable		 2vdvE-5gyrA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_F_SAMF1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 5gyr CYTOCHROME C'
(Allochromatium
vinosum) 		5 / 11 GLY A  24
GLY A  20
ASN A  29
ALA A  28
GLU A  17
 None
 1.27A 2vdvF-5gyrA:
undetectable		 2vdvF-5gyrA:
16.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLD_A_ASCA130_0
(CYTOCHROME C')		 5gyr CYTOCHROME C'
(Allochromatium
vinosum) 		4 / 5 GLY A 118
CYH A 121
LYS A 122
HIS A 125
 None
HEM  A 201 (-2.2A)
None
HEM  A 201 (-3.4A)
 0.51A 2yldA-5gyrA:
5.3		 2yldA-5gyrA:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 5gyr CYTOCHROME C'
(Allochromatium
vinosum) 		4 / 5 GLY A 118
CYH A 121
LYS A 122
HIS A 125
 None
HEM  A 201 (-2.2A)
None
HEM  A 201 (-3.4A)
 0.47A 2ylgA-5gyrA:
5.3		 2ylgA-5gyrA:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZWI_A_ASCA156_0
(CYTOCHROME C')		 5gyr CYTOCHROME C'
(Allochromatium
vinosum) 		4 / 5 GLY A 118
CYH A 121
LYS A 122
HIS A 125
 None
HEM  A 201 (-2.2A)
None
HEM  A 201 (-3.4A)
 0.61A 3zwiA-5gyrA:
5.3		 3zwiA-5gyrA:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 5gyr CYTOCHROME C'
(Allochromatium
vinosum) 		4 / 5 GLY A 118
CYH A 121
LYS A 122
HIS A 125
 None
HEM  A 201 (-2.2A)
None
HEM  A 201 (-3.4A)
 0.46A 5jliA-5gyrA:
5.3		 5jliA-5gyrA:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JRA_A_ASCA202_0
(CYTOCHROME C')		 5gyr CYTOCHROME C'
(Allochromatium
vinosum) 		4 / 4 GLY A 118
CYH A 121
LYS A 122
HIS A 125
 None
HEM  A 201 (-2.2A)
None
HEM  A 201 (-3.4A)
 0.55A 5jraA-5gyrA:
5.2		 5jraA-5gyrA:
32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 5gyr CYTOCHROME C'
(Allochromatium
vinosum) 		4 / 5 GLY A 118
CYH A 121
LYS A 122
HIS A 125
 None
HEM  A 201 (-2.2A)
None
HEM  A 201 (-3.4A)
 0.48A 5jt4A-5gyrA:
5.2		 5jt4A-5gyrA:
32.09