SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gyy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA652_1
(AMYLOMALTASE)		 5gyy S-LOCUS PROTEIN 11
S-RECEPTOR KINASE
SRK9
(Brassica
rapa) 		4 / 6 GLY G  20
ASP G  23
GLY A  47
SER G  15
 None
 0.72A 1eswA-5gyyG:
undetectable		 1eswA-5gyyG:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_2
(HMG-COA REDUCTASE)		 5gyy S-RECEPTOR KINASE
SRK9
(Brassica
rapa) 		4 / 8 SER A  70
VAL A  75
SER A  86
ASN A  88
 None
 1.23A 1hwiB-5gyyA:
undetectable		 1hwiB-5gyyA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_1
(HMG-COA REDUCTASE)		 5gyy S-RECEPTOR KINASE
SRK9
(Brassica
rapa) 		4 / 8 SER A  70
VAL A  75
SER A  86
ASN A  88
 None
 1.23A 1hwkA-5gyyA:
undetectable		 1hwkA-5gyyA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 5gyy S-RECEPTOR KINASE
SRK9
(Brassica
rapa) 		4 / 8 SER A  70
VAL A  75
SER A  86
ASN A  88
 None
 1.23A 1hwkC-5gyyA:
undetectable		 1hwkC-5gyyA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 5gyy S-RECEPTOR KINASE
SRK9
(Brassica
rapa) 		4 / 8 SER A  70
VAL A  75
SER A  86
ASN A  88
 None
 1.24A 1hwkD-5gyyA:
undetectable		 1hwkD-5gyyA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 5gyy S-RECEPTOR KINASE
SRK9
(Brassica
rapa) 		3 / 3 PHE A 239
TRP A 255
GLU A 198
 None
 0.71A 1mogA-5gyyA:
undetectable		 1mogA-5gyyA:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 5gyy S-RECEPTOR KINASE
SRK9
(Brassica
rapa) 		4 / 8 ARG A 308
GLY A 288
ASP A 397
ARG A 309
 None
 0.79A 2f9wA-5gyyA:
undetectable
2f9wB-5gyyA:
undetectable		 2f9wA-5gyyA:
22.12
2f9wB-5gyyA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_B_SAMB302_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 5gyy S-RECEPTOR KINASE
SRK9
(Brassica
rapa) 		6 / 12 ARG A 363
GLY A 190
GLY A 368
GLY A 366
PHE A 357
ALA A 360
 None
 1.30A 3kkzB-5gyyA:
undetectable		 3kkzB-5gyyA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 5gyy S-RECEPTOR KINASE
SRK9
(Brassica
rapa) 		3 / 3 TYR A 228
LEU A 134
ARG A 230
 None
 0.72A 3sufB-5gyyA:
undetectable		 3sufB-5gyyA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 5gyy S-RECEPTOR KINASE
SRK9
(Brassica
rapa) 		5 / 12 ARG A 363
GLY A 368
GLY A 366
PHE A 357
ALA A 360
 None
 1.26A 3t7sA-5gyyA:
undetectable		 3t7sA-5gyyA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_B_SAMB300_0
(PUTATIVE
METHYLTRANSFERASE)		 5gyy S-RECEPTOR KINASE
SRK9
(Brassica
rapa) 		5 / 12 ARG A 363
GLY A 368
GLY A 366
PHE A 357
ALA A 360
 None
 1.26A 3t7sB-5gyyA:
undetectable		 3t7sB-5gyyA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 5gyy S-RECEPTOR KINASE
SRK9
(Brassica
rapa) 		5 / 12 ARG A 363
GLY A 368
GLY A 366
PHE A 357
ALA A 360
 None
 1.31A 3t7sD-5gyyA:
undetectable		 3t7sD-5gyyA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZD_A_LEVA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 5gyy S-RECEPTOR KINASE
SRK9
(Brassica
rapa) 		4 / 5 LYS A 326
ILE A 268
VAL A 277
ASP A 264
 None
 1.20A 3wzdA-5gyyA:
undetectable		 3wzdA-5gyyA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1R_A_LZUA801_1
(MUCOSA-ASSOCIATED
LYMPHOID TISSUE
LYMPHOMA
TRANSLOCATION
PROTEIN 1)		 5gyy S-RECEPTOR KINASE
SRK9
(Brassica
rapa) 		5 / 12 PHE A 108
LEU A 103
LEU A 102
LEU A 129
MET A 132
 None
 1.11A 4i1rA-5gyyA:
undetectable		 4i1rA-5gyyA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PE5_C_QELC939_1
(GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 1
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 5gyy S-RECEPTOR KINASE
SRK9
(Brassica
rapa) 		5 / 10 ARG A 337
ILE A 371
PHE A 357
PRO A 187
GLU A 211
 None
 1.41A 4pe5C-5gyyA:
undetectable
4pe5D-5gyyA:
undetectable		 4pe5C-5gyyA:
18.55
4pe5D-5gyyA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA205_0
(OXIDOREDUCTASE)		 5gyy S-LOCUS PROTEIN 11
(Brassica
rapa) 		4 / 5 SER G  12
GLY G  13
ARG G  48
PHE G  27
 None
 0.93A 4r82A-5gyyG:
undetectable
4r82B-5gyyG:
undetectable		 4r82A-5gyyG:
14.05
4r82B-5gyyG:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5gyy S-RECEPTOR KINASE
SRK9
(Brassica
rapa) 		6 / 9 LEU A 389
ALA A 356
LEU A 376
ALA A 333
LEU A 327
ALA A 358
 None
 1.26A 4z91F-5gyyA:
undetectable
4z91G-5gyyA:
undetectable
4z91H-5gyyA:
undetectable
4z91I-5gyyA:
undetectable
4z91J-5gyyA:
undetectable		 4z91F-5gyyA:
22.36
4z91G-5gyyA:
22.36
4z91H-5gyyA:
22.36
4z91I-5gyyA:
22.36
4z91J-5gyyA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 5gyy S-RECEPTOR KINASE
SRK9
(Brassica
rapa) 		5 / 11 ARG A 337
ILE A 371
PHE A 357
PRO A 187
GLU A 211
 None
 1.46A 5ewjA-5gyyA:
2.1
5ewjB-5gyyA:
undetectable		 5ewjA-5gyyA:
20.32
5ewjB-5gyyA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 5gyy S-RECEPTOR KINASE
SRK9
(Brassica
rapa) 		5 / 12 ARG A 337
ILE A 371
PHE A 357
PRO A 187
GLU A 211
 None
 1.46A 5ewjC-5gyyA:
undetectable
5ewjD-5gyyA:
undetectable		 5ewjC-5gyyA:
20.32
5ewjD-5gyyA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 5gyy S-RECEPTOR KINASE
SRK9
(Brassica
rapa) 		3 / 3 THR A  87
GLU A  92
ASN A  73
 None
 0.85A 6nj9K-5gyyA:
undetectable		 6nj9K-5gyyA:
21.85