SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gz8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E6W_C_ESTC302_1
(SHORT CHAIN
3-HYDROXYACYL-COA
DEHYDROGENASE)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		4 / 4 ALA A 224
GLN A 213
TYR A 214
LEU A 128
 None
 1.36A 1e6wC-5gz8A:
undetectable		 1e6wC-5gz8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EVA_A_ADNA498_1
(TAK1 KINASE - TAB1
CHIMERA FUSION
PROTEIN)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		6 / 11 GLY A  87
VAL A  94
ALA A 105
TYR A 150
SER A 155
LEU A 215
 None
 0.62A 2evaA-5gz8A:
19.3		 2evaA-5gz8A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GQG_B_1N1B502_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		7 / 12 VAL A  94
ALA A 105
VAL A 134
ILE A 146
THR A 148
GLY A 154
LEU A 215
 None
 0.48A 2gqgB-5gz8A:
22.5		 2gqgB-5gz8A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_C_STIC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		6 / 12 VAL A  94
ALA A 105
VAL A 134
THR A 148
GLY A 154
LEU A 215
 None
 0.34A 2hyyC-5gz8A:
19.4		 2hyyC-5gz8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_D_STID600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		6 / 12 VAL A  94
ALA A 105
ILE A 146
THR A 148
LEU A 215
ASP A 226
 None
 0.81A 2hyyD-5gz8A:
19.2		 2hyyD-5gz8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		7 / 12 VAL A  94
ALA A 105
ILE A 146
THR A 148
TYR A 150
GLY A 154
LEU A 215
 None
 0.51A 2oiqA-5gz8A:
18.8		 2oiqA-5gz8A:
26.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PL0_A_STIA200_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE LCK)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		7 / 12 ALA A 105
VAL A 134
ILE A 146
THR A 148
TYR A 150
LEU A 215
ASP A 226
 None
 0.84A 2pl0A-5gz8A:
19.1		 2pl0A-5gz8A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PL0_A_STIA200_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE LCK)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		7 / 12 VAL A  94
ALA A 105
VAL A 134
ILE A 146
THR A 148
TYR A 150
LEU A 215
 None
 0.76A 2pl0A-5gz8A:
19.1		 2pl0A-5gz8A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WGJ_A_VGHA2346_1
(HEPATOCYTE GROWTH
FACTOR RECEPTOR)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		6 / 12 GLY A  87
VAL A  94
ALA A 105
TYR A 150
GLY A 154
ASP A 226
 None
 0.61A 2wgjA-5gz8A:
18.2		 2wgjA-5gz8A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6O_A_1N1A1892_1
(EPHRIN TYPE-A
RECEPTOR 4)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		7 / 12 LYS A  84
ALA A 105
ILE A 146
THR A 148
TYR A 150
GLY A 154
LEU A 215
 None
 0.50A 2y6oA-5gz8A:
19.6		 2y6oA-5gz8A:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0E_A_B49A9000_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		7 / 11 VAL A  94
ALA A 105
VAL A 134
THR A 148
TYR A 150
GLY A 154
LEU A 215
 None
 0.69A 3g0eA-5gz8A:
17.5		 3g0eA-5gz8A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0F_A_B49A9001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		6 / 11 VAL A  94
ALA A 105
THR A 148
TYR A 150
GLY A 154
LEU A 215
 None
 0.64A 3g0fA-5gz8A:
18.5		 3g0fA-5gz8A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0F_B_B49B9001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		6 / 10 VAL A  94
ALA A 105
THR A 148
TYR A 150
GLY A 154
LEU A 215
 None
 0.62A 3g0fB-5gz8A:
18.4		 3g0fB-5gz8A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G5D_A_1N1A1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		8 / 12 VAL A  94
ALA A 105
VAL A 134
ILE A 146
THR A 148
TYR A 150
GLY A 154
LEU A 215
 None
 0.65A 3g5dA-5gz8A:
13.6		 3g5dA-5gz8A:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEG_A_BAXA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		5 / 12 VAL A  86
VAL A  94
ALA A 105
LEU A 125
THR A 148
 None
 0.64A 3hegA-5gz8A:
11.4		 3hegA-5gz8A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		3 / 3 THR A  78
LYS A 115
GLU A  75
 None
 0.95A 3ijdB-5gz8A:
undetectable		 3ijdB-5gz8A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K54_A_1N1A1_1
(TYROSINE-PROTEIN
KINASE BTK)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		7 / 12 ALA A 105
VAL A 134
ILE A 146
THR A 148
TYR A 150
GLY A 154
LEU A 215
 None
 0.65A 3k54A-5gz8A:
19.6		 3k54A-5gz8A:
24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		3 / 3 GLY A 138
TRP A  99
VAL A  80
 None
 0.77A 3n62B-5gz8A:
undetectable		 3n62B-5gz8A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		3 / 3 GLY A 138
TRP A  99
VAL A  80
 None
 0.73A 3n65B-5gz8A:
undetectable		 3n65B-5gz8A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		3 / 3 GLY A 138
TRP A  99
VAL A  80
 None
 0.74A 3n66B-5gz8A:
undetectable		 3n66B-5gz8A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_1
(TYROSINE-PROTEIN
KINASE BTK)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		7 / 12 VAL A  94
ALA A 105
VAL A 134
THR A 148
TYR A 150
GLY A 154
LEU A 215
 None
 0.58A 3octA-5gz8A:
20.4		 3octA-5gz8A:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OEZ_A_STIA601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		7 / 12 VAL A  94
ALA A 105
VAL A 134
THR A 148
TYR A 150
GLY A 154
LEU A 215
 None
 0.49A 3oezA-5gz8A:
18.6		 3oezA-5gz8A:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_1
(P38A)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		7 / 12 VAL A  86
GLY A  87
VAL A  94
ALA A 105
LEU A 125
THR A 148
ASN A 158
 None
 0.74A 3ohtA-5gz8A:
12.5		 3ohtA-5gz8A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_1
(P38A)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		6 / 12 VAL A  86
GLY A  87
VAL A  94
ALA A 105
THR A 148
LEU A 215
 None
 0.98A 3ohtA-5gz8A:
12.5		 3ohtA-5gz8A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		4 / 7 PRO A 321
ILE A 308
LEU A 305
ILE A 284
 None
 0.95A 3p50A-5gz8A:
2.3		 3p50A-5gz8A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		4 / 7 PRO A 321
ILE A 308
LEU A 305
ILE A 284
 None
 0.93A 3p50C-5gz8A:
undetectable		 3p50C-5gz8A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QLG_B_1N1B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		7 / 12 VAL A  94
ALA A 105
VAL A 134
THR A 148
TYR A 150
GLY A 154
LEU A 215
 None
 0.62A 3qlgB-5gz8A:
19.5		 3qlgB-5gz8A:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXR_A_1N1A1_1
(CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		8 / 12 VAL A  94
ALA A 105
VAL A 134
ILE A 146
THR A 148
TYR A 150
GLY A 154
LEU A 215
 None
 0.55A 3sxrA-5gz8A:
20.8		 3sxrA-5gz8A:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXR_B_1N1B2_1
(CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		7 / 12 VAL A  94
ALA A 105
VAL A 134
THR A 148
TYR A 150
GLY A 154
LEU A 215
 None
 0.51A 3sxrB-5gz8A:
20.7		 3sxrB-5gz8A:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UE4_B_DB8B601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		7 / 12 VAL A  94
ALA A 105
VAL A 134
ILE A 146
THR A 148
GLY A 154
LEU A 215
 None
 0.43A 3ue4B-5gz8A:
21.6		 3ue4B-5gz8A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZE_A_BAXA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		4 / 8 VAL A 133
VAL A 134
LEU A 215
ASP A 226
 None
 0.69A 3wzeA-5gz8A:
18.5		 3wzeA-5gz8A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BKJ_A_STIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		6 / 12 VAL A  94
ALA A 105
THR A 148
TYR A 150
LEU A 215
ASP A 226
 None
 0.77A 4bkjA-5gz8A:
18.5		 4bkjA-5gz8A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CSV_A_STIA1265_1
(SRC-ABL TYROSINE
KINASE ANCESTOR)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		6 / 12 VAL A  94
ALA A 105
VAL A 134
THR A 148
TYR A 150
LEU A 215
 None
 0.52A 4csvA-5gz8A:
19.0		 4csvA-5gz8A:
26.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MXO_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		8 / 12 VAL A  94
ALA A 105
VAL A 134
ILE A 146
THR A 148
TYR A 150
GLY A 154
ASP A 226
 None
 0.80A 4mxoA-5gz8A:
20.1		 4mxoA-5gz8A:
26.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MXO_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		8 / 12 VAL A  94
ALA A 105
VAL A 134
ILE A 146
THR A 148
TYR A 150
GLY A 154
ASP A 226
 None
 0.81A 4mxoB-5gz8A:
20.3		 4mxoB-5gz8A:
26.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MXO_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		8 / 12 VAL A  94
ALA A 105
VAL A 134
ILE A 146
THR A 148
TYR A 150
GLY A 154
LEU A 215
 None
 0.72A 4mxoB-5gz8A:
20.3		 4mxoB-5gz8A:
26.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MXX_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		7 / 12 VAL A  94
ALA A 105
VAL A 134
THR A 148
TYR A 150
GLY A 154
LEU A 215
 None
 0.71A 4mxxB-5gz8A:
19.0		 4mxxB-5gz8A:
26.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MXY_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		8 / 12 VAL A  94
ALA A 105
VAL A 134
ILE A 146
TYR A 150
GLY A 154
LEU A 215
ASP A 226
 None
 0.91A 4mxyA-5gz8A:
19.9		 4mxyA-5gz8A:
26.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MXZ_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		8 / 12 VAL A  94
ALA A 105
VAL A 134
ILE A 146
TYR A 150
GLY A 154
LEU A 215
ASP A 226
 None
 0.91A 4mxzA-5gz8A:
19.9		 4mxzA-5gz8A:
26.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		5 / 12 THR A 148
THR A 145
LEU A 136
LEU A 125
PHE A 118
 None
 1.31A 4pbhA-5gz8A:
undetectable		 4pbhA-5gz8A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		5 / 12 ALA A 105
ILE A 146
THR A 148
SER A 155
GLY A 121
 None
 0.93A 4rzvA-5gz8A:
18.3		 4rzvA-5gz8A:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		7 / 12 VAL A  94
ALA A 105
VAL A 134
ILE A 146
THR A 148
GLY A 154
LEU A 215
 None
 0.49A 4xeyB-5gz8A:
21.1		 4xeyB-5gz8A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XLI_B_1N1B600_1
(NON-SPECIFIC
PROTEIN-TYROSINE
KINASE)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		7 / 12 ALA A 105
VAL A 134
ILE A 146
THR A 148
TYR A 150
GLY A 154
LEU A 215
 None
 0.51A 4xliB-5gz8A:
22.4		 4xliB-5gz8A:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		5 / 12 VAL A  94
ALA A 105
ILE A 146
THR A 148
GLY A 121
 None
 0.64A 5hesA-5gz8A:
17.1		 5hesA-5gz8A:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		5 / 12 VAL A  94
ALA A 105
ILE A 146
THR A 148
TYR A 150
 None
 0.26A 5hesA-5gz8A:
17.1		 5hesA-5gz8A:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		5 / 12 VAL A  94
ALA A 105
ILE A 146
THR A 148
TYR A 150
 None
 0.25A 5hesB-5gz8A:
17.3		 5hesB-5gz8A:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9X_A_DB8A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		6 / 12 ALA A 105
ILE A 146
THR A 148
TYR A 150
GLY A 154
LEU A 215
 None
 0.49A 5i9xA-5gz8A:
19.6		 5i9xA-5gz8A:
24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9Y_A_1N1A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		6 / 12 ALA A 105
THR A 148
TYR A 150
GLY A 154
GLU A 161
LEU A 215
 None
 0.71A 5i9yA-5gz8A:
19.4		 5i9yA-5gz8A:
24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5P9I_A_1E8A701_1
(TYROSINE-PROTEIN
KINASE BTK)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		6 / 12 VAL A  94
ALA A 105
ILE A 146
THR A 148
GLY A 154
LEU A 215
 None
 0.67A 5p9iA-5gz8A:
18.9		 5p9iA-5gz8A:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE0_A_XINA401_1
(AP2-ASSOCIATED
PROTEIN KINASE 1)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		6 / 12 LEU A  96
ALA A 105
VAL A 134
GLY A 154
ASN A 158
LEU A 215
 None
 0.43A 5te0A-5gz8A:
19.1		 5te0A-5gz8A:
25.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		3 / 3 GLY A 138
TRP A  99
VAL A  80
 None
 0.76A 5vuoB-5gz8A:
undetectable		 5vuoB-5gz8A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		5 / 11 ALA A 224
ASP A 203
VAL A 233
ILE A 241
GLN A 257
 None
 1.17A 5y80A-5gz8A:
19.7		 5y80A-5gz8A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_0
(TYROSINE-PROTEIN
KINASE ABL1)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		7 / 12 VAL A  94
ALA A 105
VAL A 134
ILE A 146
THR A 148
LEU A 215
ASP A 226
 None
 0.88A 6hd4A-5gz8A:
19.0		 6hd4A-5gz8A:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_0
(TYROSINE-PROTEIN
KINASE ABL1)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		7 / 12 VAL A  94
ALA A 105
VAL A 134
ILE A 146
THR A 148
LEU A 215
ASP A 226
 None
 0.89A 6hd4B-5gz8A:
18.7		 6hd4B-5gz8A:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_0
(TYROSINE-PROTEIN
KINASE ABL1)		 5gz8 PROTEIN O-MANNOSE
KINASE
(Mus
musculus) 		7 / 12 VAL A  94
ALA A 105
VAL A 134
ILE A 146
THR A 148
LEU A 215
ASP A 226
 None
 0.86A 6hd6A-5gz8A:
19.0		 6hd6A-5gz8A:
14.43