SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gzt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 TRP B 690
ALA B 697
VAL B 694
 None
 0.98A 1bdwA-5gztB:
undetectable
1bdwB-5gztB:
undetectable		 1bdwA-5gztB:
5.45
1bdwB-5gztB:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 9 TYR B 564
PHE B 590
GLY B 651
ASP B 689
ASP B 767
TRP B 905
 None
 1.02A 1e9lA-5gztB:
43.1		 1e9lA-5gztB:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		7 / 9 TYR B 564
PHE B 590
GLY B 651
ASP B 689
MET B 764
TYR B 766
ASP B 767
 None
 0.73A 1e9lA-5gztB:
43.1		 1e9lA-5gztB:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 9 TYR B1051
PHE B1077
GLY B1137
ASP B1175
ASP B1253
TRP B1396
 None
 1.03A 1e9lA-5gztB:
43.1		 1e9lA-5gztB:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		7 / 9 TYR B1051
PHE B1077
GLY B1137
ASP B1175
MET B1250
TYR B1252
ASP B1253
 None
 0.87A 1e9lA-5gztB:
43.1		 1e9lA-5gztB:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 GLY B 935
LEU B 958
VAL B 997
LEU B 965
ALA B1024
 None
 0.95A 1gseB-5gztB:
undetectable		 1gseB-5gztB:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 TYR B 760
GLY B 901
MET B 810
HIS B 585
LEU B 586
 None
 1.37A 1kiaD-5gztB:
undetectable		 1kiaD-5gztB:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 GLY B1136
ASP B1091
ASN B1093
ILE B1135
LEU B1156
 None
 1.31A 1lhuA-5gztB:
undetectable		 1lhuA-5gztB:
10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 LEU B 688
PHE B 657
VAL B 598
ALA B 661
ALA B 660
 None
 1.08A 1n5xA-5gztB:
undetectable		 1n5xA-5gztB:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 LEU B 688
PHE B 657
VAL B 598
ALA B 661
ALA B 660
 None
 1.07A 1n5xB-5gztB:
undetectable		 1n5xB-5gztB:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 VAL B 850
ALA B 869
SER B 886
SER B 817
HIS B 779
 FMT  B4011 (-4.8A)
None
None
None
None
 1.40A 1nbhD-5gztB:
undetectable		 1nbhD-5gztB:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 6 LEU B 798
ALA B 741
SER B 791
THR B 765
 None
 1.34A 1tyrA-5gztB:
3.6		 1tyrA-5gztB:
7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XL6_B_SPMB3001_1
(INWARD RECTIFIER
POTASSIUM CHANNEL)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 5 ALA B 781
ALA B 785
TYR B 783
GLN B 896
 None
 0.99A 1xl6A-5gztB:
4.7
1xl6B-5gztB:
4.5		 1xl6A-5gztB:
12.96
1xl6B-5gztB:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 THR B 765
GLU B 882
HIS B 778
 None
 0.86A 1xwfC-5gztB:
undetectable		 1xwfC-5gztB:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		10 / 11 TYR B 564
PHE B 590
GLY B 651
ASP B 689
GLU B 691
MET B 764
TYR B 766
ASP B 767
TYR B 816
TRP B 905
 None
 0.49A 2a3aA-5gztB:
15.7		 2a3aA-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 11 TYR B 564
PHE B 590
GLY B 651
TRP B 652
ASP B 689
GLU B 691
MET B 764
TRP B 905
 None
 0.68A 2a3aA-5gztB:
15.7		 2a3aA-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		10 / 11 TYR B1051
PHE B1077
GLY B1137
ASP B1175
GLU B1177
MET B1250
TYR B1252
ASP B1253
TYR B1304
TRP B1396
 None
 0.60A 2a3aA-5gztB:
15.7		 2a3aA-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		10 / 11 TYR B1051
PHE B1077
GLY B1137
TRP B1138
ASP B1175
GLU B1177
MET B1250
TYR B1252
ASP B1253
TRP B1396
 None
 0.67A 2a3aA-5gztB:
15.7		 2a3aA-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 TRP B 652
GLU B 691
TYR B 692
 None
 0.48A 2a3aA-5gztB:
15.7		 2a3aA-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 TRP B1138
GLU B1177
TYR B1178
 None
 0.44A 2a3aA-5gztB:
15.7		 2a3aA-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 9 PHE B 590
GLY B 651
GLU B 691
MET B 764
TYR B 766
ASP B 767
TYR B 816
TRP B 905
 None
 0.51A 2a3aB-5gztB:
41.3		 2a3aB-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 9 PHE B1077
GLY B1137
GLU B1177
MET B1250
TYR B1252
ASP B1253
TYR B1304
TRP B1396
 None
 0.62A 2a3aB-5gztB:
41.3		 2a3aB-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1433_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 5 TRP B 652
TYR B 692
MET B 764
ASP B 767
 None
 0.73A 2a3bA-5gztB:
41.5		 2a3bA-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 11 PHE B 590
GLY B 651
TRP B 652
ASP B 689
GLU B 691
MET B 764
TYR B 766
ASP B 767
TRP B 905
 None
 0.82A 2a3bA-5gztB:
41.5		 2a3bA-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 11 PHE B 590
GLY B 651
TRP B 652
ASP B 689
MET B 764
TYR B 766
ASP B 767
TYR B 816
TRP B 905
 None
 0.66A 2a3bA-5gztB:
41.5		 2a3bA-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 11 TYR B 564
PHE B 590
GLY B 651
ASP B 689
GLU B 691
MET B 764
TYR B 766
ASP B 767
TRP B 905
 None
 0.73A 2a3bA-5gztB:
41.5		 2a3bA-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 11 TYR B 564
PHE B 590
GLY B 651
ASP B 689
MET B 764
TYR B 766
ASP B 767
TYR B 816
TRP B 905
 None
 0.50A 2a3bA-5gztB:
41.5		 2a3bA-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 11 TYR B1051
PHE B1077
GLY B1137
ASP B1175
GLU B1177
MET B1250
TYR B1252
ASP B1253
TRP B1396
 None
 0.75A 2a3bA-5gztB:
41.5		 2a3bA-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 11 TYR B1051
PHE B1077
GLY B1137
ASP B1175
MET B1250
TYR B1252
ASP B1253
TYR B1304
TRP B1396
 None
 0.55A 2a3bA-5gztB:
41.5		 2a3bA-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 10 PHE B 590
GLY B 651
ASP B 689
GLU B 691
MET B 764
TYR B 766
ASP B 767
TRP B 905
 None
 0.71A 2a3bB-5gztB:
41.2		 2a3bB-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 10 PHE B 590
GLY B 651
ASP B 689
MET B 764
TYR B 766
ASP B 767
TYR B 816
TRP B 905
 None
 0.43A 2a3bB-5gztB:
41.2		 2a3bB-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 10 PHE B1077
GLY B1137
ASP B1175
GLU B1177
MET B1250
TYR B1252
ASP B1253
TRP B1396
 None
 0.73A 2a3bB-5gztB:
41.2		 2a3bB-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 10 PHE B1077
GLY B1137
ASP B1175
MET B1250
TYR B1252
ASP B1253
TYR B1304
TRP B1396
 None
 0.48A 2a3bB-5gztB:
41.2		 2a3bB-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		10 / 12 TYR B 564
TRP B 568
PHE B 590
GLY B 651
ASP B 689
GLU B 691
MET B 764
TYR B 766
ASP B 767
TRP B 905
 None
 0.72A 2a3cA-5gztB:
41.1		 2a3cA-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		10 / 12 TYR B 564
TRP B 568
PHE B 590
GLY B 651
ASP B 689
MET B 764
TYR B 766
ASP B 767
TYR B 816
TRP B 905
 None
 0.49A 2a3cA-5gztB:
41.1		 2a3cA-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		10 / 12 TYR B1051
TRP B1055
PHE B1077
GLY B1137
ASP B1175
GLU B1177
MET B1250
TYR B1252
ASP B1253
TRP B1396
 None
 0.74A 2a3cA-5gztB:
41.1		 2a3cA-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		10 / 12 TYR B1051
TRP B1055
PHE B1077
GLY B1137
ASP B1175
MET B1250
TYR B1252
ASP B1253
TYR B1304
TRP B1396
 None
 0.56A 2a3cA-5gztB:
41.1		 2a3cA-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 12 TRP B 568
PHE B 590
GLY B 651
ASP B 689
GLU B 691
MET B 764
TYR B 766
ASP B 767
TRP B 905
 None
 0.70A 2a3cB-5gztB:
41.2		 2a3cB-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 12 TRP B 568
PHE B 590
GLY B 651
ASP B 689
MET B 764
TYR B 766
ASP B 767
TYR B 816
TRP B 905
 None
 0.46A 2a3cB-5gztB:
41.2		 2a3cB-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 12 TRP B1055
PHE B1077
GLY B1137
ASP B1175
GLU B1177
MET B1250
TYR B1252
ASP B1253
TRP B1396
 None
 0.73A 2a3cB-5gztB:
41.2		 2a3cB-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 12 TRP B1055
PHE B1077
GLY B1137
ASP B1175
MET B1250
TYR B1252
ASP B1253
TYR B1304
TRP B1396
 None
 0.53A 2a3cB-5gztB:
41.2		 2a3cB-5gztB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_1
(CATECHOL
O-METHYLTRANSFERASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 6 SER B 840
TYR B 816
SER B 777
GLN B 789
 None
 1.33A 2cl5B-5gztB:
undetectable		 2cl5B-5gztB:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 PHE B 355
VAL B 313
VAL B 296
LEU A 254
LEU A 273
 None
 1.01A 2hc4A-5gztB:
undetectable		 2hc4A-5gztB:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 ARG B 704
ILE B 701
TRP B 690
 None
 1.15A 2nodB-5gztB:
undetectable		 2nodB-5gztB:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 6 THR B 795
THR B 746
THR B 755
ASP B 759
 None
 1.24A 2okcB-5gztB:
undetectable		 2okcB-5gztB:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 9 TYR B 564
PHE B 590
GLY B 651
ASP B 689
TYR B 766
TRP B 905
 None
 0.88A 2uy4A-5gztB:
18.8		 2uy4A-5gztB:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 9 TYR B 564
PHE B 590
GLY B 651
GLU B 691
TYR B 766
TRP B 905
 None
 0.44A 2uy4A-5gztB:
18.8		 2uy4A-5gztB:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 9 TYR B1051
PHE B1077
GLY B1137
ASP B1175
TYR B1252
TRP B1396
 None
 0.92A 2uy4A-5gztB:
18.8		 2uy4A-5gztB:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 9 TYR B1051
PHE B1077
GLY B1137
GLU B1177
TYR B1252
TRP B1396
 None
 0.53A 2uy4A-5gztB:
18.8		 2uy4A-5gztB:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 10 ILE B 686
PHE B 670
TYR B 587
LEU B 715
LEU B 714
 None
 1.41A 2w98A-5gztB:
undetectable		 2w98A-5gztB:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 11 TYR B 564
PHE B 590
GLY B 651
ASP B 689
TYR B 766
TRP B 905
 None
 1.03A 2xtkA-5gztB:
19.6		 2xtkA-5gztB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 11 TYR B 564
PHE B 590
GLY B 651
GLU B 691
TYR B 766
TRP B 905
 None
 0.74A 2xtkA-5gztB:
19.6		 2xtkA-5gztB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 11 TYR B1051
PHE B1077
GLY B1137
ASP B1175
TYR B1252
TRP B1396
 None
 1.03A 2xtkA-5gztB:
19.6		 2xtkA-5gztB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 11 TYR B1051
PHE B1077
GLY B1137
GLU B1177
TYR B1252
TRP B1396
 None
 0.75A 2xtkA-5gztB:
19.6		 2xtkA-5gztB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 10 TYR B 564
PHE B 590
GLY B 651
ASP B 689
TYR B 766
TRP B 905
 None
 0.96A 2xtkB-5gztB:
19.7		 2xtkB-5gztB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 10 TYR B 564
PHE B 590
GLY B 651
GLU B 691
TYR B 766
TRP B 905
 None
 0.57A 2xtkB-5gztB:
19.7		 2xtkB-5gztB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 10 TYR B1051
PHE B1077
GLY B1137
ASP B1175
TYR B1252
TRP B1396
 None
 0.99A 2xtkB-5gztB:
19.7		 2xtkB-5gztB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 10 TYR B1051
PHE B1077
GLY B1137
GLU B1177
TYR B1252
TRP B1396
 None
 0.64A 2xtkB-5gztB:
19.7		 2xtkB-5gztB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 9 LEU B1174
ILE B1135
GLY B1136
LEU B1221
LEU B1132
 None
 1.05A 3ai9X-5gztB:
undetectable		 3ai9X-5gztB:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 7 GLY B 740
ASP B 767
TRP B 772
ARG B 818
 None
 0.99A 3arrA-5gztB:
39.4		 3arrA-5gztB:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 7 GLY B 740
ASP B 767
TRP B 772
ARG B 818
 None
 1.04A 3aruA-5gztB:
41.2		 3aruA-5gztB:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_B_SALB1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 9 ARG B 377
THR B 379
VAL B 380
LEU B 402
ALA B 417
 None
 1.25A 3ax7B-5gztB:
undetectable		 3ax7B-5gztB:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 8 LEU B 688
PHE B 657
ALA B 661
ALA B 660
 None
 1.00A 3ax9B-5gztB:
undetectable		 3ax9B-5gztB:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_4
(HIV-1 PROTEASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 4 LEU A 243
ASP A 231
VAL A 270
THR A 274
 None
 0.92A 3cyxB-5gztA:
undetectable		 3cyxB-5gztA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		11 / 11 TYR B 564
PHE B 590
GLY B 651
TRP B 652
ASP B 689
GLU B 691
MET B 764
TYR B 766
ASP B 767
TYR B 816
TRP B 905
 None
 0.58A 3g6mA-5gztB:
42.2		 3g6mA-5gztB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		10 / 11 TYR B1051
PHE B1077
GLY B1137
ASP B1175
GLU B1177
MET B1250
TYR B1252
ASP B1253
TYR B1304
TRP B1396
 None
 0.62A 3g6mA-5gztB:
42.2		 3g6mA-5gztB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 11 TYR B1051
PHE B1077
GLY B1137
TRP B1138
ASP B1175
GLU B1177
MET B1250
TYR B1304
TRP B1396
 None
 0.70A 3g6mA-5gztB:
42.2		 3g6mA-5gztB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA427_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 5 TRP B 652
TYR B 692
MET B 764
ASP B 767
TRP B 772
 None
 0.67A 3g6mA-5gztB:
42.2		 3g6mA-5gztB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA427_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 5 TYR B1178
MET B1250
ASP B1253
TRP B1258
 None
 0.56A 3g6mA-5gztB:
42.2		 3g6mA-5gztB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB201_1
(PROTEIN S100-A4)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 8 GLY B 740
ILE B 754
PHE B 670
PHE B 657
 None
 0.83A 3ko0B-5gztB:
undetectable
3ko0J-5gztB:
undetectable		 3ko0B-5gztB:
6.27
3ko0J-5gztB:
6.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 8 GLY B 740
ILE B 754
PHE B 670
PHE B 657
 None
 0.86A 3ko0K-5gztB:
undetectable
3ko0S-5gztB:
undetectable		 3ko0K-5gztB:
6.27
3ko0S-5gztB:
6.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 ARG B 704
ILE B 701
TRP B 690
 None
 1.12A 3nw2B-5gztB:
undetectable		 3nw2B-5gztB:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_A_NCAA302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 8 LEU B1132
ASP B1173
ALA B1222
SER B1248
 None
 1.09A 3rodA-5gztB:
undetectable		 3rodA-5gztB:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 8 LEU B 688
PHE B 657
VAL B 598
ALA B 660
 None
 0.53A 3uniB-5gztB:
undetectable		 3uniB-5gztB:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 8 LEU B1174
PHE B1143
VAL B1085
ALA B1146
 None
 0.52A 3uniB-5gztB:
undetectable		 3uniB-5gztB:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 THR B 975
ASP B1015
VAL B 943
PRO B 980
LEU B 951
 FMT  B4008 (-4.4A)
None
None
None
None
 1.13A 3v8vA-5gztB:
undetectable		 3v8vA-5gztB:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 11 PHE B 590
GLY B 651
ASP B 689
MET B 764
TYR B 766
ASP B 767
TYR B 816
TRP B 905
 None
 0.74A 3wqvA-5gztB:
43.8		 3wqvA-5gztB:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		10 / 11 PHE B 590
GLY B 651
TRP B 652
GLU B 691
MET B 764
TYR B 766
ASP B 767
TYR B 816
ARG B 818
TRP B 905
 None
 0.52A 3wqvA-5gztB:
43.8		 3wqvA-5gztB:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		7 / 11 PHE B1077
GLY B1137
ASP B1175
TYR B1252
ASP B1253
TYR B1304
TRP B1396
 None
 0.84A 3wqvA-5gztB:
43.8		 3wqvA-5gztB:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 11 PHE B1077
GLY B1137
GLU B1177
MET B1250
TYR B1252
ASP B1253
TYR B1304
ARG B1306
TRP B1396
 None
 0.75A 3wqvA-5gztB:
43.8		 3wqvA-5gztB:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 11 PHE B1077
GLY B1137
TRP B1138
GLU B1177
MET B1250
TYR B1252
ASP B1253
TYR B1304
TRP B1396
 None
 0.76A 3wqvA-5gztB:
43.8		 3wqvA-5gztB:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 11 PHE B 590
GLY B 651
ASP B 689
MET B 764
TYR B 766
ASP B 767
TYR B 816
TRP B 905
 None
 0.77A 3wqwA-5gztB:
43.7		 3wqwA-5gztB:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		10 / 11 PHE B 590
GLY B 651
TRP B 652
GLU B 691
MET B 764
TYR B 766
ASP B 767
TYR B 816
ARG B 818
TRP B 905
 None
 0.57A 3wqwA-5gztB:
43.7		 3wqwA-5gztB:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		7 / 11 PHE B1077
GLY B1137
ASP B1175
TYR B1252
ASP B1253
TYR B1304
TRP B1396
 None
 0.87A 3wqwA-5gztB:
43.7		 3wqwA-5gztB:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 11 PHE B1077
GLY B1137
GLU B1177
MET B1250
TYR B1252
ASP B1253
TYR B1304
ARG B1306
TRP B1396
 None
 0.78A 3wqwA-5gztB:
43.7		 3wqwA-5gztB:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 11 PHE B1077
GLY B1137
TRP B1138
GLU B1177
MET B1250
TYR B1252
ASP B1253
TYR B1304
TRP B1396
 None
 0.79A 3wqwA-5gztB:
43.7		 3wqwA-5gztB:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_1
(PROTEASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 9 LEU B 688
ALA B 674
ASP B 676
VAL B 647
ILE B 649
 None
 1.46A 3wsjA-5gztB:
undetectable		 3wsjA-5gztB:
7.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 8 TYR B1254
VAL B1249
TYR B1252
ILE B1299
 None
 1.27A 4bqtC-5gztB:
undetectable
4bqtD-5gztB:
undetectable		 4bqtC-5gztB:
11.52
4bqtD-5gztB:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 6 LEU B 798
ALA B 741
SER B 791
THR B 765
 None
 1.08A 4d7bB-5gztB:
undetectable		 4d7bB-5gztB:
7.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 TYR B1243
THR B1198
GLU B1206
 None
 0.80A 4df3A-5gztB:
undetectable		 4df3A-5gztB:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 TYR B1243
THR B1198
GLU B1206
 None
 0.79A 4df3B-5gztB:
undetectable		 4df3B-5gztB:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 11 ALA B 542
SER B 538
PHE B 524
VAL B 466
THR B 547
 None
 1.30A 4eilA-5gztB:
2.5		 4eilA-5gztB:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 10 ALA B 542
SER B 538
PHE B 524
VAL B 466
THR B 547
 None
 1.40A 4eilB-5gztB:
undetectable		 4eilB-5gztB:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_C_FOLC703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 11 ALA B 542
SER B 538
PHE B 524
VAL B 466
THR B 547
 None
 1.26A 4eilC-5gztB:
undetectable		 4eilC-5gztB:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 11 ALA B 542
SER B 538
PHE B 524
VAL B 466
THR B 547
 None
 1.31A 4eilE-5gztB:
undetectable		 4eilE-5gztB:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 11 ALA B 542
SER B 538
PHE B 524
VAL B 466
THR B 547
 None
 1.30A 4kyaA-5gztB:
undetectable		 4kyaA-5gztB:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_C_FOLC703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 10 ALA B 542
SER B 538
PHE B 524
VAL B 466
THR B 547
 None
 1.27A 4kyaC-5gztB:
undetectable		 4kyaC-5gztB:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 11 ALA B 542
SER B 538
PHE B 524
VAL B 466
THR B 547
 None
 1.27A 4kyaE-5gztB:
undetectable		 4kyaE-5gztB:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_G_FOLG703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 11 ALA B 542
SER B 538
PHE B 524
VAL B 466
THR B 547
 None
 1.28A 4kyaG-5gztB:
2.5		 4kyaG-5gztB:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 7 LEU B 798
ALA B 741
SER B 791
THR B 765
 None
 1.03A 4pwjB-5gztB:
undetectable		 4pwjB-5gztB:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 ALA B1078
ILE B1073
ASN B1074
TYR B1118
ASP B1112
 None
 1.28A 4rtpA-5gztB:
undetectable		 4rtpA-5gztB:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTS_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 GLY B1142
GLY B1136
ILE B1223
SER B1225
PRO B1179
 FMT  B4007 (-3.4A)
None
None
None
None
 1.24A 4rtsA-5gztB:
undetectable		 4rtsA-5gztB:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 5 GLY B 333
THR B 332
GLY B 314
GLU B 326
 NA  B4001 ( 4.3A)
None
None
NA  B4001 (-2.6A)
 1.13A 4v20A-5gztB:
undetectable		 4v20A-5gztB:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 10 ASP B 687
ALA B 739
ILE B 754
LEU B 758
LEU B 715
 None
 1.18A 4xj7A-5gztB:
undetectable
4xj7B-5gztB:
undetectable		 4xj7A-5gztB:
13.09
4xj7B-5gztB:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 10 LEU B 758
LEU B 715
ASP B 687
ALA B 739
ILE B 754
 None
 1.17A 4xj7C-5gztB:
undetectable
4xj7D-5gztB:
undetectable		 4xj7C-5gztB:
13.09
4xj7D-5gztB:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 4 PHE B1077
ASP B1173
GLY B1137
SER B1134
 None
 1.33A 4xp9C-5gztB:
undetectable		 4xp9C-5gztB:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_B_SAMB303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 GLY B1054
TYR B1167
ASN B1074
SER B1399
GLN B1400
 None
 1.49A 4xueB-5gztB:
undetectable		 4xueB-5gztB:
11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 VAL B 397
ILE B 389
LYS B 396
ILE B 408
LEU B 339
 None
 1.22A 4y0pA-5gztB:
undetectable		 4y0pA-5gztB:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 LEU B 809
LEU B 763
ILE B 761
LEU B 758
ILE B 737
 None
 0.73A 4y0rA-5gztB:
undetectable		 4y0rA-5gztB:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1007_1
(SERUM ALBUMIN)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 9 LEU B1156
LEU B1174
ILE B1172
SER B1134
ALA B1078
 None
 1.17A 4z69A-5gztB:
undetectable		 4z69A-5gztB:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5gzt CHITINASE
CHITINASE
(Paenibacillus
sp.
FPU-7;
Paenibacillus
sp.
FPU-7) 		4 / 6 LYS B 299
GLU A 256
GLY A 278
GLY A 279
 None
 0.86A 5a06D-5gztB:
undetectable		 5a06D-5gztB:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_F_SAMF301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 PRO A 239
GLY A 257
GLY A 259
GLY A 261
LEU A 253
 None
 0.91A 5c0oF-5gztA:
undetectable		 5c0oF-5gztA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 6 SER A 255
GLU A 256
GLY A 219
GLY A 240
 None
 0.90A 5cdnR-5gztA:
undetectable
5cdnS-5gztA:
undetectable		 5cdnR-5gztA:
13.47
5cdnS-5gztA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 7 PHE B 711
SER B 658
ALA B 661
PRO B 693
 None
 0.98A 5dzkD-5gztB:
1.9
5dzkR-5gztB:
undetectable		 5dzkD-5gztB:
11.94
5dzkR-5gztB:
3.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 7 PHE B1197
SER B1144
ALA B1147
PRO B1179
 None
FMT  B4007 (-4.8A)
None
None
 0.94A 5dzkD-5gztB:
1.9
5dzkR-5gztB:
undetectable		 5dzkD-5gztB:
11.94
5dzkR-5gztB:
3.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 8 PHE B1197
SER B1144
ALA B1147
PRO B1179
 None
FMT  B4007 (-4.8A)
None
None
 0.95A 5dzkd-5gztB:
1.6
5dzkr-5gztB:
undetectable		 5dzkd-5gztB:
11.94
5dzkr-5gztB:
3.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 8 PHE B1197
SER B1144
ALA B1147
PRO B1179
 None
FMT  B4007 (-4.8A)
None
None
 0.94A 5dzkF-5gztB:
1.6
5dzkT-5gztB:
undetectable		 5dzkF-5gztB:
11.94
5dzkT-5gztB:
3.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 TYR B1231
ILE B1161
PHE B1143
GLY B1171
PHE B1197
 None
 1.21A 5fsaA-5gztB:
undetectable		 5fsaA-5gztB:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 TRP B 652
GLU B 691
ASP B 767
 None
 0.33A 5gqbA-5gztB:
41.7		 5gqbA-5gztB:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 TRP B1138
GLU B1177
ASP B1253
 None
 0.45A 5gqbA-5gztB:
41.7		 5gqbA-5gztB:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 8 PHE B 590
GLY B 651
TRP B 652
GLU B 691
TYR B 766
ASP B 767
ARG B 818
TRP B 905
 None
 0.53A 5gqbA-5gztB:
41.7		 5gqbA-5gztB:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 8 PHE B1077
GLY B1137
TRP B1138
GLU B1177
TYR B1252
ASP B1253
ARG B1306
TRP B1396
 None
 0.79A 5gqbA-5gztB:
41.7		 5gqbA-5gztB:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 6 PHE B 590
SER B 648
VAL B 647
ASP B 626
 None
 1.26A 5hesA-5gztB:
undetectable		 5hesA-5gztB:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 7 ILE B1410
GLY B1408
PHE B1342
ASP B1401
 None
 0.87A 5hieA-5gztB:
undetectable		 5hieA-5gztB:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_2
(PROTEASE E35D-SQV)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 9 LEU B1407
ILE B1299
GLY B1392
ILE B1047
ILE B1410
 None
 1.12A 5kqxB-5gztB:
undetectable		 5kqxB-5gztB:
6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_B_6J3B201_0
(TRANSTHYRETIN)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 6 LEU B 798
ALA B 741
SER B 791
THR B 765
 None
 1.11A 5l4iB-5gztB:
undetectable		 5l4iB-5gztB:
7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 8 SER B1274
ALA B1263
THR B1371
ALA B1356
 None
 0.78A 5te8B-5gztB:
undetectable		 5te8B-5gztB:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_B_RITB602_1
(CYTOCHROME P450 3A5)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 LEU B 751
ALA B 736
ALA B 900
ILE B 894
GLY B 812
 None
 1.06A 5veuB-5gztB:
undetectable		 5veuB-5gztB:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 GLN B 514
TYR B 506
ASN B 511
 None
 0.78A 6dwdC-5gztB:
undetectable		 6dwdC-5gztB:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 7 SER B1274
ALA B1263
THR B1371
ALA B1356
 None
 1.00A 6ma7A-5gztB:
undetectable		 6ma7A-5gztB:
4.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 5gzt CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 9 ILE B 737
ALA B 739
GLY B 740
GLY B 696
TYR B 695
 None
 1.31A 6nm4B-5gztB:
undetectable		 6nm4B-5gztB:
10.22