SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5gzu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 9 TYR A 564
PHE A 590
GLY A 651
ASP A 689
ASP A 767
TRP A 905
 None
 1.00A 1e9lA-5gzuA:
43.3		 1e9lA-5gzuA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		7 / 9 TYR A 564
PHE A 590
GLY A 651
ASP A 689
MET A 764
TYR A 766
ASP A 767
 None
 0.71A 1e9lA-5gzuA:
43.3		 1e9lA-5gzuA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 9 TYR A1051
PHE A1077
GLY A1137
ASP A1175
ASP A1253
TRP A1396
 None
 1.03A 1e9lA-5gzuA:
43.3		 1e9lA-5gzuA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		7 / 9 TYR A1051
PHE A1077
GLY A1137
ASP A1175
MET A1250
TYR A1252
ASP A1253
 None
 0.89A 1e9lA-5gzuA:
43.3		 1e9lA-5gzuA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDS_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 SER A 648
VAL A 647
TYR A 564
GLY A 591
PHE A 677
 None
 1.44A 1fdsA-5gzuA:
3.0		 1fdsA-5gzuA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 GLY A 935
LEU A 958
VAL A 997
LEU A 965
ALA A1024
 None
 1.01A 1gseB-5gzuA:
undetectable		 1gseB-5gzuA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 LEU A1070
LEU A1049
SER A1134
VAL A1065
LEU A1119
 None
 1.32A 1ie9A-5gzuA:
undetectable		 1ie9A-5gzuA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 TYR A 760
GLY A 901
MET A 810
HIS A 585
LEU A 586
 None
 1.39A 1kiaD-5gzuA:
2.1		 1kiaD-5gzuA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 LEU A 688
PHE A 657
VAL A 598
ALA A 661
ALA A 660
 None
 1.05A 1n5xA-5gzuA:
undetectable		 1n5xA-5gzuA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 LEU A 735
LEU A 688
PHE A 657
ALA A 661
ALA A 660
 None
 1.03A 1n5xA-5gzuA:
undetectable		 1n5xA-5gzuA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 LEU A 688
PHE A 657
VAL A 598
ALA A 661
ALA A 660
 None
 1.05A 1n5xB-5gzuA:
undetectable		 1n5xB-5gzuA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 LEU A 735
LEU A 688
PHE A 657
ALA A 661
ALA A 660
 None
 1.03A 1n5xB-5gzuA:
undetectable		 1n5xB-5gzuA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 ARG A1190
ILE A1187
TRP A1176
 None
 1.06A 1nodB-5gzuA:
undetectable		 1nodB-5gzuA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 ARG A1190
ILE A1187
TRP A1176
 None
 1.01A 1qomA-5gzuA:
undetectable		 1qomA-5gzuA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 6 LEU A 798
ALA A 741
SER A 791
THR A 765
 None
 1.31A 1tyrA-5gzuA:
undetectable		 1tyrA-5gzuA:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 THR A 765
GLU A 882
HIS A 778
 None
 0.90A 1xwfC-5gzuA:
undetectable		 1xwfC-5gzuA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		10 / 11 TYR A 564
PHE A 590
GLY A 651
ASP A 689
GLU A 691
MET A 764
TYR A 766
ASP A 767
TYR A 816
TRP A 905
 None
 0.51A 2a3aA-5gzuA:
11.1		 2a3aA-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 11 TYR A 564
PHE A 590
GLY A 651
TRP A 652
ASP A 689
GLU A 691
MET A 764
TRP A 905
 None
 0.72A 2a3aA-5gzuA:
11.1		 2a3aA-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		10 / 11 TYR A1051
PHE A1077
GLY A1137
ASP A1175
GLU A1177
MET A1250
TYR A1252
ASP A1253
TYR A1304
TRP A1396
 None
 0.61A 2a3aA-5gzuA:
11.1		 2a3aA-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 11 TYR A1051
PHE A1077
GLY A1137
TRP A1138
ASP A1175
GLU A1177
MET A1250
TYR A1252
TRP A1396
 None
 0.61A 2a3aA-5gzuA:
11.1		 2a3aA-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 TRP A 652
GLU A 691
TYR A 692
 None
 0.41A 2a3aA-5gzuA:
11.1		 2a3aA-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 TRP A1138
GLU A1177
TYR A1178
 None
 0.47A 2a3aA-5gzuA:
11.1		 2a3aA-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 9 PHE A 590
GLY A 651
GLU A 691
MET A 764
TYR A 766
ASP A 767
TYR A 816
TRP A 905
 None
 0.50A 2a3aB-5gzuA:
41.3		 2a3aB-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 9 PHE A1077
GLY A1137
GLU A1177
MET A1250
TYR A1252
ASP A1253
TYR A1304
TRP A1396
 None
 0.62A 2a3aB-5gzuA:
41.3		 2a3aB-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1433_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 5 TRP A 652
TYR A 692
MET A 764
ASP A 767
 None
 0.71A 2a3bA-5gzuA:
41.2		 2a3bA-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 11 TYR A 564
PHE A 590
GLY A 651
TRP A 652
ASP A 689
GLU A 691
MET A 764
TYR A 766
TRP A 905
 None
 0.76A 2a3bA-5gzuA:
41.2		 2a3bA-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		10 / 11 TYR A 564
PHE A 590
GLY A 651
TRP A 652
ASP A 689
MET A 764
TYR A 766
ASP A 767
TYR A 816
TRP A 905
 None
 0.66A 2a3bA-5gzuA:
41.2		 2a3bA-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 11 TYR A1051
PHE A1077
GLY A1137
ASP A1175
GLU A1177
MET A1250
TYR A1252
TRP A1396
 None
 0.68A 2a3bA-5gzuA:
41.2		 2a3bA-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 11 TYR A1051
PHE A1077
GLY A1137
ASP A1175
MET A1250
TYR A1252
ASP A1253
TYR A1304
TRP A1396
 None
 0.58A 2a3bA-5gzuA:
41.2		 2a3bA-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 11 TYR A1051
PHE A1077
GLY A1137
TRP A1138
ASP A1175
ASP A1253
TYR A1304
TRP A1396
 None
 0.83A 2a3bA-5gzuA:
41.2		 2a3bA-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		7 / 11 TYR A1051
PHE A1077
GLY A1137
TRP A1138
ASP A1175
GLU A1177
TRP A1396
 None
 0.81A 2a3bA-5gzuA:
41.2		 2a3bA-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 6 GLU A1177
TYR A1178
ASP A1253
ARG A1306
 None
 0.80A 2a3bB-5gzuA:
41.2		 2a3bB-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 10 PHE A 590
GLY A 651
ASP A 689
GLU A 691
MET A 764
TYR A 766
ASP A 767
TRP A 905
 None
 0.69A 2a3bB-5gzuA:
41.2		 2a3bB-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 10 PHE A 590
GLY A 651
ASP A 689
MET A 764
TYR A 766
ASP A 767
TYR A 816
TRP A 905
 None
 0.47A 2a3bB-5gzuA:
41.2		 2a3bB-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 10 PHE A1077
GLY A1137
ASP A1175
GLU A1177
MET A1250
TYR A1252
ASP A1253
TRP A1396
 None
 0.72A 2a3bB-5gzuA:
41.2		 2a3bB-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 10 PHE A1077
GLY A1137
ASP A1175
MET A1250
TYR A1252
ASP A1253
TYR A1304
TRP A1396
 None
 0.52A 2a3bB-5gzuA:
41.2		 2a3bB-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		10 / 12 TYR A 564
TRP A 568
PHE A 590
GLY A 651
ASP A 689
GLU A 691
MET A 764
TYR A 766
ASP A 767
TRP A 905
 None
 0.72A 2a3cA-5gzuA:
9.6		 2a3cA-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		10 / 12 TYR A 564
TRP A 568
PHE A 590
GLY A 651
ASP A 689
MET A 764
TYR A 766
ASP A 767
TYR A 816
TRP A 905
 None
 0.54A 2a3cA-5gzuA:
9.6		 2a3cA-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		10 / 12 TYR A1051
TRP A1055
PHE A1077
GLY A1137
ASP A1175
GLU A1177
MET A1250
TYR A1252
ASP A1253
TRP A1396
 None
 0.73A 2a3cA-5gzuA:
9.6		 2a3cA-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		10 / 12 TYR A1051
TRP A1055
PHE A1077
GLY A1137
ASP A1175
MET A1250
TYR A1252
ASP A1253
TYR A1304
TRP A1396
 None
 0.60A 2a3cA-5gzuA:
9.6		 2a3cA-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 12 TRP A 568
PHE A 590
GLY A 651
ASP A 689
GLU A 691
MET A 764
TYR A 766
ASP A 767
TRP A 905
 None
 0.69A 2a3cB-5gzuA:
41.2		 2a3cB-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 12 TRP A 568
PHE A 590
GLY A 651
ASP A 689
MET A 764
TYR A 766
ASP A 767
TYR A 816
TRP A 905
 None
 0.51A 2a3cB-5gzuA:
41.2		 2a3cB-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 12 TRP A1055
PHE A1077
GLY A1137
ASP A1175
GLU A1177
MET A1250
TYR A1252
ASP A1253
TRP A1396
 None
 0.73A 2a3cB-5gzuA:
41.2		 2a3cB-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 12 TRP A1055
PHE A1077
GLY A1137
ASP A1175
MET A1250
TYR A1252
ASP A1253
TYR A1304
TRP A1396
 None
 0.58A 2a3cB-5gzuA:
41.2		 2a3cB-5gzuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_1
(CATECHOL
O-METHYLTRANSFERASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 6 SER A 840
TYR A 816
SER A 777
GLN A 789
 None
 1.33A 2cl5B-5gzuA:
undetectable		 2cl5B-5gzuA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 ARG A1190
ILE A1187
TRP A1176
 None
 1.03A 2nodB-5gzuA:
undetectable		 2nodB-5gzuA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 6 THR A 795
THR A 746
THR A 755
ASP A 759
 None
 1.22A 2okcB-5gzuA:
undetectable		 2okcB-5gzuA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 6 LEU A 849
TYR A 846
ILE A 854
ARG A 861
 None
 0.98A 2q8hA-5gzuA:
undetectable		 2q8hA-5gzuA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 9 TYR A 564
PHE A 590
GLY A 651
ASP A 689
TYR A 766
TRP A 905
 None
 0.86A 2uy4A-5gzuA:
19.0		 2uy4A-5gzuA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 9 TYR A 564
PHE A 590
GLY A 651
GLU A 691
TYR A 766
TRP A 905
 None
 0.42A 2uy4A-5gzuA:
19.0		 2uy4A-5gzuA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 9 TYR A1051
PHE A1077
GLY A1137
ASP A1175
TYR A1252
TRP A1396
 None
 0.89A 2uy4A-5gzuA:
19.0		 2uy4A-5gzuA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 9 TYR A1051
PHE A1077
GLY A1137
GLU A1177
TYR A1252
TRP A1396
 None
 0.49A 2uy4A-5gzuA:
19.0		 2uy4A-5gzuA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 10 ILE A 686
PHE A 670
TYR A 587
LEU A 715
LEU A 714
 None
 1.42A 2w98A-5gzuA:
undetectable		 2w98A-5gzuA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 11 TYR A 564
PHE A 590
GLY A 651
ASP A 689
TYR A 766
TRP A 905
 None
 0.98A 2xtkA-5gzuA:
20.1		 2xtkA-5gzuA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 11 TYR A 564
PHE A 590
GLY A 651
GLU A 691
TYR A 766
TRP A 905
 None
 0.72A 2xtkA-5gzuA:
20.1		 2xtkA-5gzuA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 11 TYR A1051
PHE A1077
GLY A1137
ASP A1175
TYR A1252
TRP A1396
 None
 0.99A 2xtkA-5gzuA:
20.1		 2xtkA-5gzuA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 11 TYR A1051
PHE A1077
GLY A1137
GLU A1177
TYR A1252
TRP A1396
 None
 0.71A 2xtkA-5gzuA:
20.1		 2xtkA-5gzuA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 10 TYR A 564
PHE A 590
GLY A 651
ASP A 689
TYR A 766
TRP A 905
 None
 0.92A 2xtkB-5gzuA:
20.2		 2xtkB-5gzuA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 10 TYR A 564
PHE A 590
GLY A 651
GLU A 691
TYR A 766
TRP A 905
 None
 0.54A 2xtkB-5gzuA:
20.2		 2xtkB-5gzuA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 10 TYR A1051
PHE A1077
GLY A1137
ASP A1175
TYR A1252
TRP A1396
 None
 0.96A 2xtkB-5gzuA:
20.2		 2xtkB-5gzuA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		6 / 10 TYR A1051
PHE A1077
GLY A1137
GLU A1177
TYR A1252
TRP A1396
 None
 0.59A 2xtkB-5gzuA:
20.2		 2xtkB-5gzuA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZTH_A_SAMA305_0
(CATECHOL
O-METHYLTRANSFERASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 GLY A1054
TYR A1167
ASN A1074
SER A1399
GLN A1400
 None
 1.45A 2zthA-5gzuA:
undetectable		 2zthA-5gzuA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 9 LEU A 688
ILE A 649
GLY A 650
LEU A 735
LEU A 646
 None
 1.12A 3ai9X-5gzuA:
undetectable		 3ai9X-5gzuA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 9 LEU A1174
ILE A1135
GLY A1136
LEU A1221
LEU A1132
 None
 1.03A 3ai9X-5gzuA:
undetectable		 3ai9X-5gzuA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARQ_A_DM5A606_1
(CHITINASE A)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 6 TRP A 652
ASP A 767
TRP A 772
ARG A 818
 None
 0.84A 3arqA-5gzuA:
40.1		 3arqA-5gzuA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 7 GLY A 740
ASP A 767
TRP A 772
ARG A 818
 None
 1.01A 3arrA-5gzuA:
40.1		 3arrA-5gzuA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 7 GLY A 740
ASP A 767
TRP A 772
ARG A 818
 None
 1.03A 3aruA-5gzuA:
40.6		 3aruA-5gzuA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 8 LEU A 688
PHE A 657
ALA A 661
ALA A 660
 None
 1.01A 3ax9B-5gzuA:
undetectable		 3ax9B-5gzuA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 GLY A1054
TYR A1167
ASN A1074
SER A1399
GLN A1400
 None
 1.43A 3bwmA-5gzuA:
undetectable		 3bwmA-5gzuA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 ARG A1190
ILE A1187
TRP A1176
 None
 1.14A 3e68A-5gzuA:
undetectable		 3e68A-5gzuA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 ARG A1190
ILE A1187
TRP A1176
 None
 1.12A 3e6tB-5gzuA:
undetectable		 3e6tB-5gzuA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 ARG A1190
ILE A1187
TRP A1176
 None
 1.06A 3e7iB-5gzuA:
undetectable		 3e7iB-5gzuA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		11 / 11 TYR A 564
PHE A 590
GLY A 651
TRP A 652
ASP A 689
GLU A 691
MET A 764
TYR A 766
ASP A 767
TYR A 816
TRP A 905
 None
 0.58A 3g6mA-5gzuA:
41.6		 3g6mA-5gzuA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		10 / 11 TYR A1051
PHE A1077
GLY A1137
ASP A1175
GLU A1177
MET A1250
TYR A1252
ASP A1253
TYR A1304
TRP A1396
 None
 0.62A 3g6mA-5gzuA:
41.6		 3g6mA-5gzuA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		10 / 11 TYR A1051
PHE A1077
GLY A1137
TRP A1138
ASP A1175
GLU A1177
MET A1250
TYR A1252
TYR A1304
TRP A1396
 None
 0.67A 3g6mA-5gzuA:
41.6		 3g6mA-5gzuA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA427_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 5 TRP A 652
TYR A 692
MET A 764
ASP A 767
TRP A 772
 None
 0.60A 3g6mA-5gzuA:
41.6		 3g6mA-5gzuA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA427_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 5 TRP A1138
TYR A1178
MET A1250
TRP A1258
 None
 1.05A 3g6mA-5gzuA:
41.6		 3g6mA-5gzuA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA427_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 5 TYR A1178
MET A1250
ASP A1253
TRP A1258
 None
 0.59A 3g6mA-5gzuA:
41.6		 3g6mA-5gzuA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB201_1
(PROTEIN S100-A4)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 8 GLY A 740
ILE A 754
PHE A 670
PHE A 657
 None
 0.81A 3ko0B-5gzuA:
undetectable
3ko0J-5gzuA:
undetectable		 3ko0B-5gzuA:
7.23
3ko0J-5gzuA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 8 GLY A 740
ILE A 754
PHE A 670
PHE A 657
 None
 0.83A 3ko0K-5gzuA:
undetectable
3ko0S-5gzuA:
undetectable		 3ko0K-5gzuA:
7.23
3ko0S-5gzuA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 ASP A1351
SER A1271
ARG A 576
 None
 0.80A 3loqA-5gzuA:
2.1		 3loqA-5gzuA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 ARG A 704
ILE A 701
TRP A 690
 None
 1.15A 3nw2A-5gzuA:
undetectable		 3nw2A-5gzuA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 ARG A1190
ILE A1187
TRP A1176
 None
 1.07A 3nw2A-5gzuA:
undetectable		 3nw2A-5gzuA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 ARG A 704
ILE A 701
TRP A 690
 None
 1.13A 3nw2B-5gzuA:
undetectable		 3nw2B-5gzuA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 ARG A1190
ILE A1187
TRP A1176
 None
 1.03A 3nw2B-5gzuA:
undetectable		 3nw2B-5gzuA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_A_NCAA302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 8 LEU A1132
ASP A1173
ALA A1222
SER A1248
 None
 1.09A 3rodA-5gzuA:
undetectable		 3rodA-5gzuA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 8 LEU A 688
PHE A 657
VAL A 598
ALA A 660
 None
 0.56A 3uniB-5gzuA:
undetectable		 3uniB-5gzuA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 8 LEU A1174
PHE A1143
VAL A1085
ALA A1146
 None
 0.51A 3uniB-5gzuA:
undetectable		 3uniB-5gzuA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 THR A 975
ASP A1015
VAL A 943
PRO A 980
LEU A 951
 None
 1.14A 3v8vA-5gzuA:
2.7		 3v8vA-5gzuA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 11 PHE A 590
GLY A 651
ASP A 689
MET A 764
TYR A 766
ASP A 767
TYR A 816
TRP A 905
 None
 0.74A 3wqvA-5gzuA:
44.1		 3wqvA-5gzuA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		10 / 11 PHE A 590
GLY A 651
TRP A 652
GLU A 691
MET A 764
TYR A 766
ASP A 767
TYR A 816
ARG A 818
TRP A 905
 None
 0.54A 3wqvA-5gzuA:
44.1		 3wqvA-5gzuA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		7 / 11 PHE A1077
GLY A1137
ASP A1175
TYR A1252
ASP A1253
TYR A1304
TRP A1396
 None
 0.82A 3wqvA-5gzuA:
44.1		 3wqvA-5gzuA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		10 / 11 PHE A1077
GLY A1137
TRP A1138
GLU A1177
MET A1250
TYR A1252
ASP A1253
TYR A1304
ARG A1306
TRP A1396
 None
 0.89A 3wqvA-5gzuA:
44.1		 3wqvA-5gzuA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 11 PHE A 590
GLY A 651
ASP A 689
MET A 764
TYR A 766
ASP A 767
TYR A 816
TRP A 905
 None
 0.77A 3wqwA-5gzuA:
44.0		 3wqwA-5gzuA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		10 / 11 PHE A 590
GLY A 651
TRP A 652
GLU A 691
MET A 764
TYR A 766
ASP A 767
TYR A 816
ARG A 818
TRP A 905
 None
 0.58A 3wqwA-5gzuA:
44.0		 3wqwA-5gzuA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		7 / 11 PHE A1077
GLY A1137
ASP A1175
TYR A1252
ASP A1253
TYR A1304
TRP A1396
 None
 0.85A 3wqwA-5gzuA:
44.0		 3wqwA-5gzuA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 11 PHE A1077
GLY A1137
GLU A1177
MET A1250
TYR A1252
ASP A1253
TYR A1304
ARG A1306
TRP A1396
 None
 0.79A 3wqwA-5gzuA:
44.0		 3wqwA-5gzuA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		9 / 11 PHE A1077
GLY A1137
TRP A1138
GLU A1177
MET A1250
TYR A1252
ASP A1253
TYR A1304
TRP A1396
 None
 0.73A 3wqwA-5gzuA:
44.0		 3wqwA-5gzuA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 8 TYR A1254
VAL A1249
TYR A1252
ILE A1299
 None
 1.28A 4bqtC-5gzuA:
undetectable
4bqtD-5gzuA:
undetectable		 4bqtC-5gzuA:
14.08
4bqtD-5gzuA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 6 LEU A 798
ALA A 741
SER A 791
THR A 765
 None
 1.06A 4d7bB-5gzuA:
undetectable		 4d7bB-5gzuA:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 8 PHE A1319
SER A1353
ALA A1356
SER A1267
 None
 1.19A 4lv9A-5gzuA:
2.1
4lv9B-5gzuA:
3.2		 4lv9A-5gzuA:
21.52
4lv9B-5gzuA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 7 PHE A1319
SER A1353
ALA A1356
SER A1267
 None
 1.20A 4lv9A-5gzuA:
2.1
4lv9B-5gzuA:
3.2		 4lv9A-5gzuA:
21.52
4lv9B-5gzuA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 5 TYR A 846
THR A 828
LEU A 830
THR A 780
 None
 1.44A 4mbsB-5gzuA:
undetectable		 4mbsB-5gzuA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 7 LEU A 798
ALA A 741
SER A 791
THR A 765
 None
 1.00A 4pwjB-5gzuA:
undetectable		 4pwjB-5gzuA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 ALA A1078
ILE A1073
ASN A1074
TYR A1118
ASP A1112
 None
 1.23A 4rtpA-5gzuA:
undetectable		 4rtpA-5gzuA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 10 ASP A 687
ALA A 739
ILE A 754
LEU A 758
LEU A 715
 None
 1.18A 4xj7A-5gzuA:
undetectable
4xj7B-5gzuA:
undetectable		 4xj7A-5gzuA:
15.39
4xj7B-5gzuA:
15.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 4 PHE A 590
ASP A 687
GLY A 651
SER A 648
 None
 1.28A 4xp9C-5gzuA:
undetectable		 4xp9C-5gzuA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 4 PHE A1077
ASP A1173
GLY A1137
SER A1134
 None
 1.35A 4xp9C-5gzuA:
undetectable		 4xp9C-5gzuA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_B_SAMB303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 GLY A1054
TYR A1167
ASN A1074
SER A1399
GLN A1400
 None
 1.39A 4xueB-5gzuA:
undetectable		 4xueB-5gzuA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 LEU A 809
LEU A 763
ILE A 761
LEU A 758
ILE A 737
 None
 0.75A 4y0rA-5gzuA:
undetectable		 4y0rA-5gzuA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1007_1
(SERUM ALBUMIN)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 9 LEU A1156
LEU A1174
ILE A1172
SER A1134
ALA A1078
 None
 1.18A 4z69A-5gzuA:
undetectable		 4z69A-5gzuA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 7 PHE A 711
SER A 658
ALA A 661
PRO A 693
 None
 0.93A 5dzkD-5gzuA:
3.6
5dzkR-5gzuA:
undetectable		 5dzkD-5gzuA:
13.90
5dzkR-5gzuA:
1.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 7 PHE A1197
SER A1144
ALA A1147
PRO A1179
 None
 0.91A 5dzkD-5gzuA:
3.6
5dzkR-5gzuA:
undetectable		 5dzkD-5gzuA:
13.90
5dzkR-5gzuA:
1.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 TYR A1231
ILE A1161
PHE A1143
GLY A1171
PHE A1197
 None
 1.17A 5fsaA-5gzuA:
undetectable		 5fsaA-5gzuA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 TRP A 652
GLU A 691
ASP A 767
 None
 0.45A 5gqbA-5gzuA:
43.3		 5gqbA-5gzuA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 TRP A1138
GLU A1177
ASP A1253
 None
 0.34A 5gqbA-5gzuA:
43.3		 5gqbA-5gzuA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 8 PHE A 590
GLY A 651
TRP A 652
GLU A 691
TYR A 766
ASP A 767
ARG A 818
TRP A 905
 None
 0.63A 5gqbA-5gzuA:
43.2		 5gqbA-5gzuA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		8 / 8 PHE A1077
GLY A1137
TRP A1138
GLU A1177
TYR A1252
ASP A1253
ARG A1306
TRP A1396
 None
 0.73A 5gqbA-5gzuA:
43.2		 5gqbA-5gzuA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 7 ILE A1410
GLY A1408
PHE A1342
ASP A1401
 None
 0.89A 5hieA-5gzuA:
undetectable		 5hieA-5gzuA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_2
(PROTEASE E35D-SQV)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 9 LEU A1407
ILE A1299
GLY A1392
ILE A1047
ILE A1410
 None
 1.11A 5kqxB-5gzuA:
undetectable		 5kqxB-5gzuA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_B_6J3B201_0
(TRANSTHYRETIN)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 6 LEU A 798
ALA A 741
SER A 791
THR A 765
 None
 1.08A 5l4iB-5gzuA:
undetectable		 5l4iB-5gzuA:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 8 SER A1274
ALA A1263
THR A1371
ALA A1356
 None
 0.75A 5te8B-5gzuA:
undetectable		 5te8B-5gzuA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_B_RITB602_1
(CYTOCHROME P450 3A5)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 LEU A 751
ALA A 736
ALA A 900
ILE A 894
GLY A 812
 None
 1.06A 5veuB-5gzuA:
undetectable		 5veuB-5gzuA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		3 / 3 VAL A 782
TYR A 893
GLU A 882
 None
 0.97A 5zmqD-5gzuA:
undetectable
5zmqE-5gzuA:
undetectable		 5zmqD-5gzuA:
12.04
5zmqE-5gzuA:
4.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 12 ILE A 761
LEU A 798
LEU A 758
THR A 712
LEU A 715
 None
 1.16A 6b54A-5gzuA:
undetectable		 6b54A-5gzuA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 6 SER A1274
ALA A1263
THR A1371
ALA A1356
 None
 1.16A 6ma6A-5gzuA:
undetectable		 6ma6A-5gzuA:
6.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		4 / 7 SER A1274
ALA A1263
THR A1371
ALA A1356
 None
 0.97A 6ma7A-5gzuA:
undetectable		 6ma7A-5gzuA:
6.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_B_NMYB302_0
(AAC(3)-IIIB PROTEIN)		 5gzu CHITINASE
(Paenibacillus
sp.
FPU-7) 		5 / 10 ASP A1253
ASP A1336
THR A1333
THR A1371
GLY A1307
 None
 1.36A 6mb9B-5gzuA:
undetectable		 6mb9B-5gzuA:
7.80