SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h07'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FCN_A_DVAA35_0
(UBIQUITIN)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 4 GLN A 131
GLU A 134
ILE A 136
PRO A 137
None
0.96A 2fcnA-5h07A:
15.7
2fcnA-5h07A:
32.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FCN_A_DVAA35_0
(UBIQUITIN)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 4 GLN A 231
GLU A 234
ILE A 236
PRO A 237
None
0.98A 2fcnA-5h07A:
15.7
2fcnA-5h07A:
32.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FCN_B_DVAB35_0
(UBIQUITIN)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 6 GLN A  31
GLU A  34
ILE A  36
PRO A  37
None
0.33A 2fcnA-5h07A:
15.7
2fcnB-5h07A:
15.2
2fcnA-5h07A:
32.89
2fcnB-5h07A:
32.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FCN_B_DVAB35_0
(UBIQUITIN)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 6 GLN A 131
GLU A 134
ILE A 136
PRO A 137
None
0.46A 2fcnA-5h07A:
15.7
2fcnB-5h07A:
15.2
2fcnA-5h07A:
32.89
2fcnB-5h07A:
32.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FCN_B_DVAB35_0
(UBIQUITIN)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 6 GLN A 231
GLU A 234
ILE A 236
PRO A 237
None
0.95A 2fcnA-5h07A:
15.7
2fcnB-5h07A:
15.2
2fcnA-5h07A:
32.89
2fcnB-5h07A:
32.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
5 / 12 SER A 157
THR A 155
LEU A 115
ILE A 103
SER A 165
None
1.45A 2fj1A-5h07A:
undetectable
2fj1A-5h07A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 7 LYS A 127
GLU A 124
ASP A 152
SER A 220
None
1.26A 3dzgA-5h07A:
undetectable
3dzgA-5h07A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MGH_A_ACTA1320_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 5 VAL A 170
ILE A 144
LEU A 143
ARG A 142
None
0.88A 4mghA-5h07A:
undetectable
4mghA-5h07A:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
3 / 3 SER A 220
ASP A 221
GLN A 131
None
0.89A 4oltA-5h07A:
undetectable
4oltB-5h07A:
undetectable
4oltA-5h07A:
23.99
4oltB-5h07A:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
3 / 3 GLN A 131
SER A 220
ASP A 221
None
0.85A 4qwpA-5h07A:
undetectable
4qwpB-5h07A:
undetectable
4qwpA-5h07A:
23.99
4qwpB-5h07A:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 7 ILE A  44
GLN A  49
ILE A  23
ASP A  52
None
1.05A 4w5oA-5h07A:
undetectable
4w5oA-5h07A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 7 ILE A 144
GLN A 149
ILE A 123
ASP A 152
None
0.87A 4w5oA-5h07A:
undetectable
4w5oA-5h07A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 7 ILE A 244
GLN A 249
ILE A 223
ASP A 252
None
0.90A 4w5oA-5h07A:
undetectable
4w5oA-5h07A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 6 ILE A  44
GLN A  49
ILE A  23
ASP A  52
None
0.99A 4w5qA-5h07A:
undetectable
4w5qA-5h07A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 6 ILE A 144
GLN A 149
ILE A 123
ASP A 152
None
0.87A 4w5qA-5h07A:
undetectable
4w5qA-5h07A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 6 ILE A 244
GLN A 249
ILE A 223
ASP A 252
None
0.90A 4w5qA-5h07A:
undetectable
4w5qA-5h07A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 6 ILE A  44
GLN A  49
ILE A  23
ASP A  52
None
0.95A 4w5tA-5h07A:
undetectable
4w5tA-5h07A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 6 ILE A  44
GLN A  49
ILE A  23
ASP A  52
None
1.00A 4z4dA-5h07A:
undetectable
4z4dA-5h07A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 6 ILE A 144
GLN A 149
ILE A 123
ASP A 152
None
0.90A 4z4dA-5h07A:
undetectable
4z4dA-5h07A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 6 ILE A 244
GLN A 249
ILE A 223
ASP A 252
None
0.90A 4z4dA-5h07A:
undetectable
4z4dA-5h07A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 7 ILE A  44
GLN A  49
ILE A  23
ASP A  52
None
0.99A 4z4eA-5h07A:
undetectable
4z4eA-5h07A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 7 ILE A 144
GLN A 149
ILE A 123
ASP A 152
None
0.88A 4z4eA-5h07A:
undetectable
4z4eA-5h07A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 7 ILE A 244
GLN A 249
ILE A 223
ASP A 252
None
0.92A 4z4eA-5h07A:
undetectable
4z4eA-5h07A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 7 ILE A  44
GLN A  49
ILE A  23
ASP A  52
None
1.02A 4z4gA-5h07A:
undetectable
4z4gA-5h07A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 7 ILE A 144
GLN A 149
ILE A 123
ASP A 152
None
0.89A 4z4gA-5h07A:
undetectable
4z4gA-5h07A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 7 ILE A 244
GLN A 249
ILE A 223
ASP A 252
None
0.90A 4z4gA-5h07A:
undetectable
4z4gA-5h07A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 6 ILE A  44
GLN A  49
ILE A  23
ASP A  52
None
1.02A 6cbdA-5h07A:
undetectable
6cbdA-5h07A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 6 ILE A 144
GLN A 149
ILE A 123
ASP A 152
None
0.95A 6cbdA-5h07A:
undetectable
6cbdA-5h07A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_H_ZOLH401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 5 ASP A 121
GLN A  31
GLN A  40
LYS A 129
None
1.38A 6g31H-5h07A:
undetectable
6g31H-5h07A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_L_ZOLL401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
5h07 POLYUBIQUITIN-C
(Homo
sapiens)
4 / 6 ASP A 121
GLN A  31
GLN A  40
LYS A 129
None
1.39A 6g31L-5h07A:
undetectable
6g31L-5h07A:
16.96