SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h0k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)		 5h0k UNCHARACTERIZED
PROTEIN
(Pedobacter
heparinus) 		6 / 12 LEU A  60
PHE A 228
PHE A 116
TYR A 121
LEU A 166
GLN A 165
 None
 1.27A 1brpA-5h0kA:
undetectable		 1brpA-5h0kA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 5h0k UNCHARACTERIZED
PROTEIN
(Pedobacter
heparinus) 		3 / 3 PHE A 219
LEU A 203
SER A 226
 None
 0.71A 1e7aA-5h0kA:
undetectable		 1e7aA-5h0kA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5h0k UNCHARACTERIZED
PROTEIN
(Pedobacter
heparinus) 		5 / 11 TYR A  46
SER A  55
VAL A   8
PHE A   4
GLN A 165
 None
 1.21A 1uduA-5h0kA:
undetectable		 1uduA-5h0kA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 5h0k UNCHARACTERIZED
PROTEIN
(Pedobacter
heparinus) 		4 / 6 PRO A  75
TYR A 121
TYR A  46
TYR A  50
 None
 1.07A 4g10A-5h0kA:
undetectable		 4g10A-5h0kA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 5h0k UNCHARACTERIZED
PROTEIN
(Pedobacter
heparinus) 		4 / 6 TYR A 121
TYR A  46
TYR A  50
PHE A  45
 None
 1.14A 4g10A-5h0kA:
undetectable		 4g10A-5h0kA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 5h0k UNCHARACTERIZED
PROTEIN
(Pedobacter
heparinus) 		4 / 8 ILE A 107
ILE A  74
PHE A  76
GLY A  61
 None
 0.98A 4hdlA-5h0kA:
undetectable		 4hdlA-5h0kA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 5h0k UNCHARACTERIZED
PROTEIN
(Pedobacter
heparinus) 		4 / 8 GLY A  61
PHE A  76
SER A  99
HIS A 205
 None
 0.44A 4wryA-5h0kA:
7.6		 4wryA-5h0kA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 5h0k UNCHARACTERIZED
PROTEIN
(Pedobacter
heparinus) 		4 / 8 GLY A  61
PHE A  76
SER A  99
HIS A 205
 None
 0.44A 4wrzA-5h0kA:
7.6		 4wrzA-5h0kA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 5h0k UNCHARACTERIZED
PROTEIN
(Pedobacter
heparinus) 		4 / 8 GLY A  61
PHE A  76
SER A  99
HIS A 205
 None
 0.32A 4ws1A-5h0kA:
7.3		 4ws1A-5h0kA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 5h0k UNCHARACTERIZED
PROTEIN
(Pedobacter
heparinus) 		5 / 12 GLY A  61
PHE A 130
THR A 131
TYR A 145
VAL A 154
 None
 1.17A 5d0yA-5h0kA:
undetectable		 5d0yA-5h0kA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 5h0k UNCHARACTERIZED
PROTEIN
(Pedobacter
heparinus) 		5 / 11 TYR A  46
TYR A 104
ILE A 103
ILE A 107
PHE A  45
 None
 1.30A 5hw8B-5h0kA:
undetectable		 5hw8B-5h0kA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 5h0k UNCHARACTERIZED
PROTEIN
(Pedobacter
heparinus) 		5 / 12 ASN A  30
GLN A 165
SER A  20
GLY A  19
THR A  18
 None
 1.40A 5oj0A-5h0kA:
undetectable		 5oj0A-5h0kA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 5h0k UNCHARACTERIZED
PROTEIN
(Pedobacter
heparinus) 		5 / 12 ILE A 103
PHE A 116
ILE A 122
ILE A 200
ALA A 202
 None
 1.07A 5vceA-5h0kA:
undetectable		 5vceA-5h0kA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 5h0k UNCHARACTERIZED
PROTEIN
(Pedobacter
heparinus) 		5 / 12 ILE A 103
PHE A 116
ILE A 122
ILE A 200
GLU A 204
 None
 0.94A 5vceA-5h0kA:
undetectable		 5vceA-5h0kA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 5h0k UNCHARACTERIZED
PROTEIN
(Pedobacter
heparinus) 		4 / 5 GLN A  37
THR A  72
THR A  84
GLY A  92
 None
 1.18A 6gbnC-5h0kA:
undetectable		 6gbnC-5h0kA:
18.72