SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h0m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 5h0m HNH ENDONUCLEASE
(Geobacillus
virus
E2) 		3 / 4 LYS A  71
ALA A  67
MET A 107
 None
 1.05A 1hk3A-5h0mA:
undetectable		 1hk3A-5h0mA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5h0m HNH ENDONUCLEASE
(Geobacillus
virus
E2) 		4 / 6 LEU A 110
LEU A  97
TRP A  61
PHE A  55
 None
 1.30A 1ru9H-5h0mA:
undetectable
1ru9L-5h0mA:
undetectable		 1ru9H-5h0mA:
19.28
1ru9L-5h0mA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5h0m HNH ENDONUCLEASE
(Geobacillus
virus
E2) 		4 / 6 LEU A 110
LEU A  97
TRP A  61
PHE A  55
 None
 1.32A 1rukH-5h0mA:
undetectable
1rukL-5h0mA:
undetectable		 1rukH-5h0mA:
19.28
1rukL-5h0mA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 5h0m HNH ENDONUCLEASE
(Geobacillus
virus
E2) 		4 / 6 VAL A  91
LEU A  66
THR A  64
TRP A  61
 None
 1.31A 5ogjA-5h0mA:
undetectable		 5ogjA-5h0mA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 5h0m HNH ENDONUCLEASE
(Geobacillus
virus
E2) 		4 / 6 VAL A  91
LEU A  66
THR A  64
TRP A  61
 None
 1.30A 5ohhB-5h0mA:
undetectable		 5ohhB-5h0mA:
19.77