SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h0q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_C_ACTC506_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5h0q LIPID BINDING
PROTEIN
(Grifola
frondosa) 		4 / 5 ARG A  90
TRP A 132
HIS A 104
GLY A 116
 None
 1.50A 4e7cC-5h0qA:
undetectable		 4e7cC-5h0qA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_B_PARB500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 5h0q LIPID BINDING
PROTEIN
(Grifola
frondosa) 		5 / 9 SER A  80
THR A 105
SER A 107
GLU A  54
GLY A  86
 None
 1.16A 4qb9B-5h0qA:
0.0		 4qb9B-5h0qA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5h0q LIPID BINDING
PROTEIN
(Grifola
frondosa) 		4 / 5 TYR A 198
TYR A 200
TYR A 120
GLY A 121
 None
 1.06A 5ayfA-5h0qA:
undetectable		 5ayfA-5h0qA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 5h0q LIPID BINDING
PROTEIN
(Grifola
frondosa) 		3 / 3 TRP A 155
GLU A  79
ASP A 161
 None
 1.06A 5gqbA-5h0qA:
undetectable		 5gqbA-5h0qA:
17.72