SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h0r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		5 / 12 LEU G 551
HIS G 296
LEU G 273
GLY G 297
PHE G 362
 None
 1.29A 1d4fA-5h0rG:
undetectable		 1d4fA-5h0rG:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		5 / 12 LEU G 551
HIS G 296
LEU G 273
GLY G 297
PHE G 362
 None
 1.32A 1d4fB-5h0rG:
undetectable		 1d4fB-5h0rG:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		5 / 12 LEU G 551
HIS G 296
LEU G 273
GLY G 297
PHE G 362
 None
 1.31A 1d4fC-5h0rG:
undetectable		 1d4fC-5h0rG:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		5 / 12 LEU G 551
HIS G 296
LEU G 273
GLY G 297
PHE G 362
 None
 1.39A 1d4fD-5h0rG:
undetectable		 1d4fD-5h0rG:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		4 / 4 LEU G   7
PRO G   6
LEU G  20
ARG G  21
 None
 1.06A 1hrkB-5h0rG:
undetectable		 1hrkB-5h0rG:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_2
(CES1 PROTEIN)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		4 / 4 LEU G 175
PRO G   6
ILE G  52
LEU G  56
 None
 1.12A 1ya4B-5h0rG:
undetectable		 1ya4B-5h0rG:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA703_0
(FERROCHELATASE)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		4 / 4 LEU G   7
PRO G   6
LEU G  20
ARG G  21
 None
 1.22A 2hrcA-5h0rG:
undetectable		 2hrcA-5h0rG:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		4 / 4 LEU G   7
PRO G   6
LEU G  20
ARG G  21
 None
 1.10A 2hrcB-5h0rG:
undetectable		 2hrcB-5h0rG:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		5 / 12 ILE G   4
TYR G  13
LEU G  18
PHE G 202
TYR G 197
 None
 1.08A 2mjiA-5h0rG:
undetectable		 2mjiA-5h0rG:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		4 / 4 LEU G   7
PRO G   6
LEU G  20
ARG G  21
 None
 1.07A 2pnjB-5h0rG:
undetectable		 2pnjB-5h0rG:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_D_VD3D2001_1
(VITAMIN D
HYDROXYLASE)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		5 / 12 PRO G   6
ILE G 172
LEU G 154
ILE G  77
ALA G  74
 None
 1.01A 3a50D-5h0rG:
undetectable		 3a50D-5h0rG:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_A_SALA257_1
(TRANSCRIPTIONAL
REGULATOR)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		4 / 8 ALA G  74
THR G 177
ILE G 176
THR G 179
 None
 0.62A 3bpxA-5h0rG:
undetectable
3bpxB-5h0rG:
undetectable		 3bpxA-5h0rG:
12.66
3bpxB-5h0rG:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		5 / 12 GLY G 489
GLN G 494
LEU G 456
LEU G 530
THR G 513
 None
 1.30A 3cldA-5h0rG:
undetectable		 3cldA-5h0rG:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_2
(HIV-1 PROTEASE)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		3 / 3 ARG G 483
VAL G 350
THR G 501
 None
 0.68A 3cyxA-5h0rG:
undetectable		 3cyxA-5h0rG:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		5 / 12 LEU G 551
HIS G 296
LEU G 273
GLY G 297
PHE G 362
 None
 1.39A 3g1uA-5h0rG:
undetectable		 3g1uA-5h0rG:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		5 / 12 LEU G 551
HIS G 296
LEU G 273
GLY G 297
PHE G 362
 None
 1.39A 3g1uC-5h0rG:
undetectable		 3g1uC-5h0rG:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		5 / 12 LEU G 551
HIS G 296
LEU G 273
GLY G 297
PHE G 362
 None
 1.35A 3glqA-5h0rG:
undetectable		 3glqA-5h0rG:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		5 / 12 LEU G 551
HIS G 296
LEU G 273
GLY G 297
PHE G 362
 None
 1.36A 3glqB-5h0rG:
undetectable		 3glqB-5h0rG:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		5 / 12 LEU G 551
HIS G 296
LEU G 273
GLY G 297
PHE G 362
 None
 1.35A 3n58A-5h0rG:
undetectable		 3n58A-5h0rG:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRM_A_VD3A502_1
(VITAMIN D(3)
25-HYDROXYLASE)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		5 / 12 PRO G   6
ILE G 172
LEU G 154
ILE G  77
ALA G  74
 None
 1.02A 3vrmA-5h0rG:
undetectable		 3vrmA-5h0rG:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		3 / 3 TYR G 290
MET G 550
LEU G 363
 None
 0.83A 3vw1D-5h0rG:
undetectable		 3vw1D-5h0rG:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		4 / 5 TYR G 352
GLN G 494
SER G 383
ASP G 512
 None
 1.40A 4qtuB-5h0rG:
undetectable		 4qtuB-5h0rG:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		5 / 12 ALA G 357
GLY G 356
ALA G 516
THR G 513
ASP G 519
 None
 1.20A 4qvpV-5h0rG:
undetectable
4qvpW-5h0rG:
undetectable		 4qvpV-5h0rG:
18.53
4qvpW-5h0rG:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_4_BEZ4801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		4 / 5 LEU G 294
PHE G 286
ILE G 510
ILE G 307
 None
 0.94A 5dzk4-5h0rG:
undetectable
5dzkg-5h0rG:
undetectable
5dzkm-5h0rG:
undetectable
5dzkn-5h0rG:
undetectable		 5dzk4-5h0rG:
0.68
5dzkg-5h0rG:
17.65
5dzkm-5h0rG:
15.86
5dzkn-5h0rG:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		3 / 3 THR G 513
ASP G 532
GLU G 438
 None
 0.80A 5fa8A-5h0rG:
undetectable		 5fa8A-5h0rG:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		5 / 12 GLY G 489
TYR G 534
SER G 467
PHE G 471
TYR G 472
 None
 1.35A 5igwA-5h0rG:
undetectable		 5igwA-5h0rG:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		5 / 12 LEU G 551
HIS G 296
LEU G 273
GLY G 297
PHE G 362
 None
 1.37A 6aphA-5h0rG:
undetectable		 6aphA-5h0rG:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_1
(-)		 5h0r VP4 PROTEIN
(Cypovirus
1) 		5 / 12 LEU G 551
HIS G 296
LEU G 273
GLY G 297
PHE G 362
 None
 1.31A 6gbnB-5h0rG:
undetectable		 6gbnB-5h0rG:
22.47