SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h11'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 5h11 UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		4 / 7 PHE A 444
PHE A 447
PHE A 500
PHE A 496
 None
 1.01A 1lh6A-5h11A:
2.3		 1lh6A-5h11A:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T46_A_STIA3_2
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)		 5h11 UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		4 / 7 VAL A 583
VAL A 590
TYR A 481
CYH A 542
 None
 1.20A 1t46A-5h11A:
undetectable		 1t46A-5h11A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 5h11 UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		3 / 3 GLN A 619
HIS A 615
ARG A 612
 None
 1.07A 1zlqA-5h11A:
undetectable		 1zlqA-5h11A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 5h11 UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		4 / 5 ASP A 537
LEU A 540
MET A 543
ARG A 609
 None
 1.28A 2gj5A-5h11A:
undetectable		 2gj5A-5h11A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 5h11 UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		3 / 3 GLU A 347
ASP A 351
ASP A 438
 None
 0.51A 3jb2A-5h11A:
2.1		 3jb2A-5h11A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_2
(VITAMIN D3 RECEPTOR)		 5h11 UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		5 / 9 LEU A 613
ARG A 589
LEU A 603
TYR A 638
VAL A 579
 None
 1.30A 3m7rA-5h11A:
undetectable		 3m7rA-5h11A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5h11 UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		4 / 5 VAL A 530
PHE A 493
ILE A 525
PHE A 496
 None
 1.10A 3owxB-5h11A:
undetectable		 3owxB-5h11A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_A_HFGA702_0
(AMINOACYL-TRNA
SYNTHETASE)		 5h11 UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		5 / 12 LEU A 606
GLY A 584
GLU A 588
VAL A 590
ARG A 589
 None
 1.27A 5f9zA-5h11A:
undetectable		 5f9zA-5h11A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_2
(CYCLIN-DEPENDENT
KINASE 6)		 5h11 UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		3 / 3 LYS A 330
GLN A 255
ASN A 258
 None
 1.06A 5l2tA-5h11A:
undetectable		 5l2tA-5h11A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MSD_A_BEZA1202_0
(CARBOXYLIC ACID
REDUCTASE)		 5h11 UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		4 / 5 HIS A 458
ILE A 459
SER A 412
ALA A 489
 None
 1.20A 5msdA-5h11A:
2.1		 5msdA-5h11A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCV_A_1N1A404_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 5h11 UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		4 / 5 HIS A 611
LEU A 663
CYH A 661
ASP A 655
 None
 1.49A 5vcvA-5h11A:
undetectable		 5vcvA-5h11A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 5h11 UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		3 / 3 HIS A 425
GLU A 422
ASN A 418
 None
None
BR  A 809 ( 4.7A)
 1.00A 5wbvA-5h11A:
undetectable		 5wbvA-5h11A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 5h11 UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		3 / 3 HIS A 425
GLU A 422
ASN A 418
 None
None
BR  A 809 ( 4.7A)
 1.00A 5wbvB-5h11A:
undetectable		 5wbvB-5h11A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 5h11 UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		4 / 5 LEU A 219
VAL A 215
GLU A 199
LEU A 196
 None
 1.00A 5xooB-5h11A:
undetectable		 5xooB-5h11A:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5h11 UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		3 / 3 GLN A 620
ILE A 632
HIS A 658
 None
 0.68A 5z12B-5h11A:
undetectable		 5z12B-5h11A:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 5h11 UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		6 / 12 VAL A 246
ASP A 245
LEU A 307
LEU A 433
LEU A 292
GLN A 302
 None
 1.47A 6ew0B-5h11A:
undetectable		 6ew0B-5h11A:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 5h11 UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		6 / 12 VAL A 246
ASP A 245
LEU A 307
LEU A 433
LEU A 292
GLN A 302
 None
 1.47A 6ew0D-5h11A:
undetectable		 6ew0D-5h11A:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 5h11 UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		6 / 12 VAL A 246
ASP A 245
LEU A 307
LEU A 433
LEU A 292
GLN A 302
 None
 1.47A 6ew0H-5h11A:
undetectable		 6ew0H-5h11A:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 5h11 UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		6 / 12 VAL A 246
ASP A 245
LEU A 307
LEU A 433
LEU A 292
GLN A 302
 None
 1.47A 6ew0I-5h11A:
undetectable		 6ew0I-5h11A:
11.16