SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h1d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_C_TPFC2471_1
(CYTOCHROME P450 121)		 5h1d RHO GDP-DISSOCIATION
INHIBITOR 2
(Homo
sapiens) 		4 / 8 VAL A 109
ASN A 174
PHE A 141
ALA A 139
 None
 1.09A 2ij7C-5h1dA:
undetectable		 2ij7C-5h1dA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 5h1d RHO GDP-DISSOCIATION
INHIBITOR 2
(Homo
sapiens) 		3 / 3 HIS A 128
LYS A 175
PHE A 177
 None
 1.38A 5klaA-5h1dA:
undetectable		 5klaA-5h1dA:
14.97