SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h1k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 GLN A 509
HIS A 510
ALA A 497
GLU A 504
HIS A 539
 None
 1.26A 1kxhA-5h1kA:
undetectable		 1kxhA-5h1kA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 8 SER A 604
ASN A 605
GLU A 541
GLY A 554
 None
A  C  10 ( 3.7A)
None
None
 0.92A 1meiA-5h1kA:
undetectable		 1meiA-5h1kA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		3 / 3 ARG A 260
ILE A 253
TRP A 254
 None
 1.11A 1qomA-5h1kA:
undetectable		 1qomA-5h1kA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_1
(POL POLYPROTEIN)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 9 LEU A 147
ILE A 175
ILE A 178
VAL A 134
ILE A 149
 None
 1.11A 2avoA-5h1kA:
undetectable		 2avoA-5h1kA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_1
(POL POLYPROTEIN)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.81A 2f80A-5h1kA:
undetectable		 2f80A-5h1kA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.77A 2f80B-5h1kA:
undetectable		 2f80B-5h1kA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.85A 2f81A-5h1kA:
undetectable		 2f81A-5h1kA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.91A 2f81B-5h1kA:
undetectable		 2f81B-5h1kA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.84A 2f8gA-5h1kA:
undetectable		 2f8gA-5h1kA:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_1
(POL PROTEIN)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 11 ILE A 178
GLY A 193
ASP A 195
ILE A 251
VAL A 176
 None
 1.10A 2fxdA-5h1kA:
undetectable		 2fxdA-5h1kA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.89A 2ienB-5h1kA:
undetectable		 2ienB-5h1kA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_A_SC2A1290_1
(FICOLIN-2)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 5 ASP A 557
SER A 559
LEU A 553
GLY A 554
 None
 1.22A 2j2pA-5h1kA:
undetectable
2j2pB-5h1kA:
undetectable		 2j2pA-5h1kA:
15.63
2j2pB-5h1kA:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.76A 2pymA-5h1kA:
undetectable		 2pymA-5h1kA:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.75A 2pymB-5h1kA:
undetectable		 2pymB-5h1kA:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.76A 2pynA-5h1kA:
undetectable		 2pynA-5h1kA:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.76A 2pynB-5h1kA:
undetectable		 2pynB-5h1kA:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 8 ASP A 652
HIS A 587
SER A 648
HIS A 650
 None
 0.99A 2q0iA-5h1kA:
undetectable		 2q0iA-5h1kA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.76A 2q63B-5h1kA:
undetectable		 2q63B-5h1kA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.74A 2qakB-5h1kA:
undetectable		 2qakB-5h1kA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 7 THR A 634
VAL A 608
SER A 636
PRO A 631
 None
 0.99A 2v2gA-5h1kA:
undetectable
2v2gB-5h1kA:
undetectable		 2v2gA-5h1kA:
17.39
2v2gB-5h1kA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 7 PRO A 631
THR A 634
VAL A 608
SER A 636
 None
 0.97A 2v2gA-5h1kA:
undetectable
2v2gB-5h1kA:
undetectable		 2v2gA-5h1kA:
17.39
2v2gB-5h1kA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 7 THR A 634
VAL A 608
SER A 636
PRO A 631
 None
 1.00A 2v2gC-5h1kA:
undetectable
2v2gD-5h1kA:
undetectable		 2v2gC-5h1kA:
17.39
2v2gD-5h1kA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 7 PRO A 631
THR A 634
VAL A 608
SER A 636
 None
 0.98A 2v2gC-5h1kA:
undetectable
2v2gD-5h1kA:
undetectable		 2v2gC-5h1kA:
17.39
2v2gD-5h1kA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 8 THR A 634
VAL A 608
SER A 636
PRO A 631
 None
 1.00A 2v32A-5h1kA:
undetectable
2v32B-5h1kA:
undetectable		 2v32A-5h1kA:
17.39
2v32B-5h1kA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 8 PRO A 631
THR A 634
VAL A 608
SER A 636
 None
 0.94A 2v32A-5h1kA:
undetectable
2v32B-5h1kA:
undetectable		 2v32A-5h1kA:
17.39
2v32B-5h1kA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 8 PRO A 631
THR A 634
VAL A 608
SER A 636
 None
 0.96A 2v32C-5h1kA:
undetectable
2v32D-5h1kA:
undetectable		 2v32C-5h1kA:
17.39
2v32D-5h1kA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 8 PRO A 631
THR A 634
VAL A 608
SER A 636
 None
 0.97A 2v41C-5h1kA:
undetectable
2v41D-5h1kA:
undetectable		 2v41C-5h1kA:
17.39
2v41D-5h1kA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 7 THR A 634
VAL A 608
SER A 636
PRO A 631
 None
 1.04A 2v41E-5h1kA:
undetectable
2v41F-5h1kA:
undetectable		 2v41E-5h1kA:
17.39
2v41F-5h1kA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 7 PRO A 631
THR A 634
VAL A 608
SER A 636
 None
 0.99A 2v41E-5h1kA:
undetectable
2v41F-5h1kA:
undetectable		 2v41E-5h1kA:
17.39
2v41F-5h1kA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 6 LEU A 352
ILE A 366
PRO A 292
VAL A  96
 None
 1.17A 2ygoA-5h1kA:
undetectable		 2ygoA-5h1kA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 GLY A 445
GLY A 449
ASP A 448
LEU A 476
TYR A 474
 None
 1.25A 2zw9A-5h1kA:
8.8		 2zw9A-5h1kA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_2
(HIV-1 PROTEASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.78A 3cywB-5h1kA:
undetectable		 3cywB-5h1kA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_2
(HIV-1 PROTEASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.83A 3d20B-5h1kA:
undetectable		 3d20B-5h1kA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		3 / 3 ARG A 260
ILE A 253
TRP A 254
 None
 1.10A 3e7iB-5h1kA:
undetectable		 3e7iB-5h1kA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 5 PRO A 512
THR A 446
VAL A 473
GLY A 445
 None
 1.18A 3elzA-5h1kA:
undetectable		 3elzA-5h1kA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 10 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.86A 3em3A-5h1kA:
undetectable		 3em3A-5h1kA:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_B_SAMB301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 GLY A 128
SER A 113
THR A 114
ASP A 129
ILE A 149
 None
 1.24A 3iv6B-5h1kA:
undetectable		 3iv6B-5h1kA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.82A 3jvyA-5h1kA:
undetectable		 3jvyA-5h1kA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.80A 3jvyB-5h1kA:
undetectable		 3jvyB-5h1kA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 10 ILE A 628
SER A 657
TRP A 667
ALA A 669
ALA A 601
 None
 1.40A 3lw5B-5h1kA:
undetectable		 3lw5B-5h1kA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.76A 3lzsA-5h1kA:
undetectable		 3lzsA-5h1kA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.82A 3lzsB-5h1kA:
undetectable		 3lzsB-5h1kA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.81A 3lzuA-5h1kA:
undetectable		 3lzuA-5h1kA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.82A 3ndtD-5h1kA:
undetectable		 3ndtD-5h1kA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_1
(PROTEASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.83A 3nduC-5h1kA:
undetectable		 3nduC-5h1kA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_A_ACTA601_0
(CHOLINE OXIDASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 5 ILE A 526
HIS A 539
VAL A 507
ASN A 523
 None
 1.32A 3nneA-5h1kA:
undetectable		 3nneA-5h1kA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 10 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.90A 3nu6B-5h1kA:
undetectable		 3nu6B-5h1kA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		3 / 3 ARG A 260
ILE A 253
TRP A 254
 None
 1.14A 3nw2B-5h1kA:
undetectable		 3nw2B-5h1kA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_1
(PROTEASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.75A 3pwmA-5h1kA:
undetectable		 3pwmA-5h1kA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_2
(PROTEASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.93A 3pwmB-5h1kA:
undetectable		 3pwmB-5h1kA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.81A 3pwrB-5h1kA:
undetectable		 3pwrB-5h1kA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_1
(PROTEASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.78A 3tkwA-5h1kA:
undetectable		 3tkwA-5h1kA:
8.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 ASP A 248
HIS A 199
GLY A 174
GLY A 193
ASP A 173
 None
 1.17A 4blvA-5h1kA:
undetectable		 4blvA-5h1kA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_A_RKEA401_1
(PROTON-GATED ION
CHANNEL)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 8 ASP A  95
VAL A  36
PHE A  72
LEU A  27
 None
 0.75A 4f8hA-5h1kA:
undetectable
4f8hB-5h1kA:
undetectable		 4f8hA-5h1kA:
18.78
4f8hB-5h1kA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_B_RKEB401_1
(PROTON-GATED ION
CHANNEL)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 8 ASP A  95
VAL A  36
PHE A  72
LEU A  27
 None
 0.81A 4f8hB-5h1kA:
undetectable
4f8hC-5h1kA:
undetectable		 4f8hB-5h1kA:
18.78
4f8hC-5h1kA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_C_RKEC401_1
(PROTON-GATED ION
CHANNEL)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 8 ASP A  95
VAL A  36
PHE A  72
LEU A  27
 None
 0.77A 4f8hC-5h1kA:
undetectable
4f8hD-5h1kA:
undetectable		 4f8hC-5h1kA:
18.78
4f8hD-5h1kA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_D_RKED401_1
(PROTON-GATED ION
CHANNEL)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 8 ASP A  95
VAL A  36
PHE A  72
LEU A  27
 None
 0.77A 4f8hD-5h1kA:
undetectable
4f8hE-5h1kA:
undetectable		 4f8hD-5h1kA:
18.78
4f8hE-5h1kA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_E_RKEE401_1
(PROTON-GATED ION
CHANNEL)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 8 VAL A  36
PHE A  72
LEU A  27
ASP A  95
 None
 0.79A 4f8hA-5h1kA:
undetectable
4f8hE-5h1kA:
undetectable		 4f8hA-5h1kA:
18.78
4f8hE-5h1kA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		3 / 3 ASP A 696
ARG A   6
THR A 712
 None
 0.89A 4i13A-5h1kA:
undetectable		 4i13A-5h1kA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 6 ARG A  33
GLY A 379
ASP A 704
HIS A 708
 U  C   6 ( 3.8A)
None
None
None
 1.22A 4lajA-5h1kA:
undetectable
4lajB-5h1kA:
undetectable		 4lajA-5h1kA:
21.47
4lajB-5h1kA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_2
(PROTEASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 9 ARG A 190
VAL A 167
GLY A 128
VAL A 177
ILE A 179
 None
 1.24A 4ll3B-5h1kA:
undetectable		 4ll3B-5h1kA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 8 SER A 200
HIS A 194
ILE A 253
TRP A 254
 None
 1.06A 4ms4A-5h1kA:
undetectable		 4ms4A-5h1kA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A  81
LEU A  60
VAL A 101
HIS A  63
VAL A  67
 None
 1.37A 4okxA-5h1kA:
undetectable		 4okxA-5h1kA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		3 / 3 GLY A 479
PRO A 480
GLN A 509
 None
 0.52A 4oltB-5h1kA:
undetectable		 4oltB-5h1kA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		3 / 3 ASP A 696
ARG A   6
THR A 712
 None
 0.87A 4p3rA-5h1kA:
undetectable		 4p3rA-5h1kA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 375
PHE A  37
VAL A  39
THR A   7
SER A 700
 None
 1.21A 4q15A-5h1kA:
undetectable		 4q15A-5h1kA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_0
(PROLINE--TRNA LIGASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 375
PHE A  37
VAL A  39
THR A   7
SER A 700
 None
 1.23A 4q15B-5h1kA:
undetectable		 4q15B-5h1kA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		3 / 3 GLY A 479
PRO A 480
GLN A 509
 None
 0.46A 4qwpB-5h1kA:
undetectable		 4qwpB-5h1kA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		3 / 3 THR A 529
ASN A 530
SER A 531
 None
 0.75A 4tvtA-5h1kA:
undetectable		 4tvtA-5h1kA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 5 GLU A 283
THR A 288
HIS A 290
LEU A 308
 None
 1.27A 5axaA-5h1kA:
undetectable		 5axaA-5h1kA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 5 GLU A 283
THR A 288
HIS A 290
LEU A 308
 None
 1.25A 5axaC-5h1kA:
undetectable		 5axaC-5h1kA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 7 ILE A 550
ILE A 584
THR A 573
ILE A 574
 None
 0.72A 5fukA-5h1kA:
undetectable
5fukB-5h1kA:
undetectable		 5fukA-5h1kA:
15.86
5fukB-5h1kA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_C_ACTC1403_0
(L-THREONINE
3-DEHYDROGENASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 4 MET A 357
SER A 356
VAL A 337
GLY A 306
 U  C   2 ( 3.8A)
None
None
None
 1.16A 5k50C-5h1kA:
undetectable		 5k50C-5h1kA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		3 / 3 VAL A 656
VAL A 666
GLN A 715
 None
 0.59A 5qgjA-5h1kA:
undetectable		 5qgjA-5h1kA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		3 / 3 VAL A 656
VAL A 666
GLN A 715
 None
 0.60A 5qgmA-5h1kA:
undetectable		 5qgmA-5h1kA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		3 / 3 VAL A 656
VAL A 666
GLN A 715
 None
 0.61A 5qgnA-5h1kA:
undetectable		 5qgnA-5h1kA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		3 / 3 VAL A 656
VAL A 666
GLN A 715
 None
 0.60A 5qgyA-5h1kA:
undetectable		 5qgyA-5h1kA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		3 / 3 VAL A 656
VAL A 666
GLN A 715
 None
 0.60A 5qgzA-5h1kA:
undetectable		 5qgzA-5h1kA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		3 / 3 VAL A 656
VAL A 666
GLN A 715
 None
 0.58A 5qh0A-5h1kA:
undetectable		 5qh0A-5h1kA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		3 / 3 VAL A 656
VAL A 666
GLN A 715
 None
 0.61A 5qh2A-5h1kA:
undetectable		 5qh2A-5h1kA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		3 / 3 VAL A 656
VAL A 666
GLN A 715
 None
 0.61A 5qh3A-5h1kA:
undetectable		 5qh3A-5h1kA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		3 / 3 VAL A 656
VAL A 666
GLN A 715
 None
 0.62A 5qh5A-5h1kA:
undetectable		 5qh5A-5h1kA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		3 / 3 VAL A 656
VAL A 666
GLN A 715
 None
 0.61A 5qh6A-5h1kA:
undetectable		 5qh6A-5h1kA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		3 / 3 VAL A 656
VAL A 666
GLN A 715
 None
 0.60A 5qh7A-5h1kA:
undetectable		 5qh7A-5h1kA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		3 / 3 VAL A 656
VAL A 666
GLN A 715
 None
 0.60A 5qhaA-5h1kA:
undetectable		 5qhaA-5h1kA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		3 / 3 VAL A 656
VAL A 666
GLN A 715
 None
 0.58A 5qhhA-5h1kA:
undetectable		 5qhhA-5h1kA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 6 THR A 250
ARG A 252
ILE A 198
GLU A 197
 None
None
None
U  C   3 ( 4.9A)
 1.22A 5uigA-5h1kA:
undetectable		 5uigA-5h1kA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 VAL A 167
ILE A 179
ILE A 149
VAL A 126
HIS A 108
 None
 1.00A 5uvmB-5h1kA:
undetectable		 5uvmB-5h1kA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 375
PHE A  37
VAL A  39
THR A   7
SER A 700
 None
 1.24A 5xipA-5h1kA:
undetectable		 5xipA-5h1kA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		3 / 3 SER A  20
ALA A  22
VAL A  23
 None
 0.53A 5xiwC-5h1kA:
undetectable		 5xiwC-5h1kA:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YSI_A_NCAA1001_0
(UBIQUITINATING/DEUBI
QUITINATING ENZYME
SDEA)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 6 GLY A 170
SER A 246
THR A 244
VAL A 176
 None
 1.17A 5ysiA-5h1kA:
undetectable		 5ysiA-5h1kA:
12.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEH_A_RPTA601_1
(SCAFFOLD PROTEIN D13)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 10 GLN A 331
PRO A  12
VAL A  39
PHE A  30
PHE A  28
 None
 1.39A 6behA-5h1kA:
undetectable
6behB-5h1kA:
undetectable
6behC-5h1kA:
undetectable		 6behA-5h1kA:
20.77
6behB-5h1kA:
20.77
6behC-5h1kA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 7 ALA A 601
TYR A 610
GLN A 665
PRO A 720
 None
 0.91A 6cduA-5h1kA:
undetectable
6cduE-5h1kA:
undetectable		 6cduA-5h1kA:
18.12
6cduE-5h1kA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_B_EY4B500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 6 VAL A 656
TRP A 667
ALA A 664
THR A 663
 None
 0.98A 6cduB-5h1kA:
undetectable
6cduC-5h1kA:
undetectable		 6cduB-5h1kA:
18.12
6cduC-5h1kA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 8 VAL A 507
PRO A 537
THR A 475
TYR A 474
 None
 1.00A 6cduG-5h1kA:
undetectable
6cduH-5h1kA:
undetectable		 6cduG-5h1kA:
18.12
6cduH-5h1kA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		4 / 7 GLN A 665
PRO A 720
ALA A 601
TYR A 610
 None
 0.89A 6cduH-5h1kA:
undetectable
6cduI-5h1kA:
undetectable		 6cduH-5h1kA:
18.12
6cduI-5h1kA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.90A 6dgxA-5h1kA:
undetectable		 6dgxA-5h1kA:
7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.92A 6dh6A-5h1kA:
undetectable		 6dh6A-5h1kA:
8.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 5h1k GEM-ASSOCIATED
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 157
GLY A 132
VAL A 177
VAL A 167
ILE A 169
 None
 0.86A 6difB-5h1kA:
undetectable		 6difB-5h1kA:
7.88