SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h1s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5h1s 50S RIBOSOMAL
PROTEIN L13,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 5 PRO L 145
ILE L 135
GLY L 137
TYR L 143
 C  A 568 ( 4.7A)
None
None
None
 1.15A 2jkjF-5h1sL:
undetectable		 2jkjF-5h1sL:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5h1s 50S RIBOSOMAL
PROTEIN L13,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 8 HIS L 134
ARG L 242
ASP L 238
ILE L 237
 None
 0.91A 4l7iA-5h1sL:
undetectable		 4l7iA-5h1sL:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5h1s 50S RIBOSOMAL
PROTEIN L13,
CHLOROPLASTIC
(Spinacia
oleracea) 		3 / 3 SER L 164
ALA L 162
VAL L 161
 U  A1168 ( 3.4A)
None
None
 0.53A 4x1iA-5h1sL:
undetectable		 4x1iA-5h1sL:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5h1s 50S RIBOSOMAL
PROTEIN L13,
CHLOROPLASTIC
(Spinacia
oleracea) 		3 / 3 SER L 164
ALA L 162
VAL L 161
 U  A1168 ( 3.4A)
None
None
 0.51A 5eypA-5h1sL:
undetectable		 5eypA-5h1sL:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_A_GBMA801_1
(PROLINE--TRNA LIGASE)		 5h1s 50S RIBOSOMAL
PROTEIN L13,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 12 PHE L 188
LEU L 239
THR L 130
ILE L 131
ILE L 200
 None
 1.26A 5ifuA-5h1sL:
undetectable		 5ifuA-5h1sL:
17.41