SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h28'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_C_TOPC200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5h28 OXYSTEROL-BINDING
PROTEIN HOMOLOG 1
(Saccharomyces
cerevisiae) 		5 / 11 LEU A  56
VAL A  72
ILE A 112
PHE A 115
THR A 121
 None
 1.20A 3fl9C-5h28A:
undetectable		 3fl9C-5h28A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_1
(FIV PROTEASE)		 5h28 OXYSTEROL-BINDING
PROTEIN HOMOLOG 1
(Saccharomyces
cerevisiae) 		5 / 9 GLY A 220
ALA A 221
ASP A 222
GLY A 191
LEU A 216
 None
 0.96A 3ogpA-5h28A:
undetectable		 3ogpA-5h28A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_2
(FIV PROTEASE)		 5h28 OXYSTEROL-BINDING
PROTEIN HOMOLOG 1
(Saccharomyces
cerevisiae) 		5 / 9 GLY A 220
ALA A 221
ASP A 222
GLY A 191
LEU A 216
 None
 1.03A 3ogpB-5h28A:
undetectable		 3ogpB-5h28A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 5h28 OXYSTEROL-BINDING
PROTEIN HOMOLOG 1
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 220
ALA A 221
ASP A 222
GLY A 191
LEU A 216
 None
 0.96A 3ogqB-5h28A:
undetectable		 3ogqB-5h28A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5h28 OXYSTEROL-BINDING
PROTEIN HOMOLOG 1
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  86
PHE A  40
HIS A  57
VAL A  62
 None
 1.00A 4a97A-5h28A:
undetectable		 4a97A-5h28A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5h28 OXYSTEROL-BINDING
PROTEIN HOMOLOG 1
(Saccharomyces
cerevisiae) 		4 / 6 ILE A  86
PHE A  40
HIS A  57
VAL A  62
 None
 1.08A 4a97I-5h28A:
undetectable		 4a97I-5h28A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 5h28 OXYSTEROL-BINDING
PROTEIN HOMOLOG 1
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  68
LEU A  56
HIS A  73
ALA A 104
 None
 0.79A 4g77A-5h28A:
undetectable		 4g77A-5h28A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 5h28 OXYSTEROL-BINDING
PROTEIN HOMOLOG 1
(Saccharomyces
cerevisiae) 		5 / 12 PRO A 223
ASP A 188
ASN A 190
LEU A 216
ILE A 189
 None
 1.41A 5dv4A-5h28A:
undetectable		 5dv4A-5h28A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5h28 OXYSTEROL-BINDING
PROTEIN HOMOLOG 1
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 226
ILE A 271
PHE A 224
 None
 0.74A 5kirA-5h28A:
undetectable		 5kirA-5h28A:
16.42