SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h2a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA502_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 5h2a KLLA0C04147P
(Kluyveromyces
lactis) 		3 / 3 LEU A 237
HIS A 203
LYS A 232
 None
 1.06A 1y7iA-5h2aA:
undetectable		 1y7iA-5h2aA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 5h2a KLLA0C04147P
(Kluyveromyces
lactis) 		4 / 5 ASP A 254
LEU A 257
LYS A 258
ARG A 209
 None
 1.09A 2gj5A-5h2aA:
undetectable		 2gj5A-5h2aA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 5h2a KLLA0C04147P
(Kluyveromyces
lactis) 		5 / 12 LEU A 212
LEU A 175
ILE A 190
GLY A 221
LEU A 218
 None
 1.16A 2j7xA-5h2aA:
undetectable		 2j7xA-5h2aA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 5h2a KLLA0C04147P
(Kluyveromyces
lactis) 		4 / 6 PHE A 163
PHE A 167
GLY A 221
GLY A 222
 None
 1.01A 2qr2A-5h2aA:
undetectable
2qr2B-5h2aA:
undetectable		 2qr2A-5h2aA:
23.00
2qr2B-5h2aA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 5h2a KLLA0C04147P
(Kluyveromyces
lactis) 		4 / 5 GLY A 221
GLY A 222
PHE A 163
PHE A 167
 None
 0.97A 2qr2A-5h2aA:
undetectable
2qr2B-5h2aA:
undetectable		 2qr2A-5h2aA:
23.00
2qr2B-5h2aA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3O_A_DLUA399_1
(PFV INTEGRASE)		 5h2a KLLA0C04147P
(Kluyveromyces
lactis) 		4 / 7 ASP A  97
ASP A  95
TYR A  60
GLN A 108
 None
 1.14A 3s3oA-5h2aA:
undetectable		 3s3oA-5h2aA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5h2a KLLA0C04147P
(Kluyveromyces
lactis) 		5 / 12 GLY A 222
GLY A 221
VAL A 206
PHE A 167
PHE A 163
 None
 1.26A 4fglA-5h2aA:
undetectable
4fglB-5h2aA:
undetectable		 4fglA-5h2aA:
22.78
4fglB-5h2aA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5h2a KLLA0C04147P
(Kluyveromyces
lactis) 		5 / 12 LEU A  34
LEU A  37
ILE A  73
ILE A  89
LEU A  87
 None
 1.05A 4j24A-5h2aA:
undetectable		 4j24A-5h2aA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 5h2a KLLA0C04147P
(Kluyveromyces
lactis) 		5 / 12 LEU A  34
LEU A  37
ILE A  73
ILE A  89
LEU A  87
 None
 1.06A 4j24B-5h2aA:
undetectable		 4j24B-5h2aA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M10_A_NCAA603_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 5h2a KLLA0C04147P
(Kluyveromyces
lactis) 		4 / 5 LEU A  34
PHE A  54
LEU A  22
TRP A  77
 None
 1.27A 5m10A-5h2aA:
undetectable		 5m10A-5h2aA:
18.36