SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h2f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_G_AG2G7003_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 5h2f CYTOCHROME B559
SUBUNIT ALPHA
(Thermosynechococ
cus
elongatus) 		4 / 6 ASP E  45
LEU E  42
GLY E  41
ARG E  51
 None
 0.66A 1mt1G-5h2fE:
undetectable
1mt1J-5h2fE:
undetectable		 1mt1G-5h2fE:
14.63
1mt1J-5h2fE:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_H_AG2H7012_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 5h2f CYTOCHROME B559
SUBUNIT ALPHA
(Thermosynechococ
cus
elongatus) 		4 / 6 ARG E  51
ASP E  45
LEU E  42
GLY E  41
 None
 0.60A 1n13H-5h2fE:
undetectable
1n13K-5h2fE:
undetectable		 1n13H-5h2fE:
23.28
1n13K-5h2fE:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 5h2f CYTOCHROME B559
SUBUNIT ALPHA
(Thermosynechococ
cus
elongatus) 		4 / 7 ASP E  45
LEU E  42
GLY E  41
ARG E  51
 None
 0.61A 1n13G-5h2fE:
undetectable
1n13J-5h2fE:
undetectable		 1n13G-5h2fE:
14.63
1n13J-5h2fE:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_E_AG2E671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 5h2f CYTOCHROME B559
SUBUNIT ALPHA
(Thermosynechococ
cus
elongatus) 		4 / 7 ARG E  51
ASP E  45
LEU E  42
GLY E  41
 None
 0.67A 2qqcD-5h2fE:
undetectable
2qqcE-5h2fE:
undetectable		 2qqcD-5h2fE:
23.48
2qqcE-5h2fE:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_B_AG2B671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 5h2f CYTOCHROME B559
SUBUNIT ALPHA
(Thermosynechococ
cus
elongatus) 		4 / 8 ARG E  51
ASP E  45
LEU E  42
GLY E  41
 None
 0.57A 2qqdB-5h2fE:
undetectable
2qqdC-5h2fE:
undetectable		 2qqdB-5h2fE:
23.48
2qqdC-5h2fE:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5h2f CYTOCHROME B559
SUBUNIT ALPHA
CYTOCHROME B559
SUBUNIT BETA
(Thermosynechococ
cus
elongatus) 		4 / 8 THR E  26
LEU E  30
ALA F  27
HIS F  24
 HEM  E 102 (-3.6A)
None
HEM  E 102 (-3.4A)
HEM  E 102 (-3.3A)
 0.92A 3kp6A-5h2fE:
undetectable		 3kp6A-5h2fE:
18.00