SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h2g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5h2g DIAMINOPIMELATE
EPIMERASE
(Corynebacterium
glutamicum) 		3 / 3 ARG A 209
VAL A 195
TRP A 211
 None
 1.21A 1qwcA-5h2gA:
undetectable		 1qwcA-5h2gA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 5h2g DIAMINOPIMELATE
EPIMERASE
(Corynebacterium
glutamicum) 		4 / 4 GLY A 222
SER A 220
VAL A 245
LEU A 263
 None
 1.25A 1yajB-5h2gA:
undetectable		 1yajB-5h2gA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5h2g DIAMINOPIMELATE
EPIMERASE
(Corynebacterium
glutamicum) 		3 / 3 ARG A 209
VAL A 195
TRP A 211
 None
 1.19A 1zviA-5h2gA:
undetectable		 1zviA-5h2gA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_B_NCAB901_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 5h2g DIAMINOPIMELATE
EPIMERASE
(Corynebacterium
glutamicum) 		4 / 5 ILE A  20
PRO A  21
PHE A  90
VAL A  53
 None
 1.49A 2hjhB-5h2gA:
undetectable		 2hjhB-5h2gA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		 5h2g DIAMINOPIMELATE
EPIMERASE
(Corynebacterium
glutamicum) 		4 / 8 LEU A 179
ALA A 173
LEU A 174
GLN A 148
 None
 0.79A 3cldB-5h2gA:
undetectable		 3cldB-5h2gA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_A_ACTA401_0
(UNCHARACTERIZED
PROTEIN)		 5h2g DIAMINOPIMELATE
EPIMERASE
(Corynebacterium
glutamicum) 		5 / 9 GLY A  84
SER A 220
CYH A 221
GLY A 222
THR A 223
 None
 1.18A 4lb0A-5h2gA:
20.8		 4lb0A-5h2gA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		 5h2g DIAMINOPIMELATE
EPIMERASE
(Corynebacterium
glutamicum) 		4 / 7 VAL A 128
PRO A 266
LYS A 244
GLU A 253
 None
 1.07A 4lb2A-5h2gA:
undetectable		 4lb2A-5h2gA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5h2g DIAMINOPIMELATE
EPIMERASE
(Corynebacterium
glutamicum) 		3 / 3 ARG A 209
VAL A 195
TRP A 211
 None
 1.16A 5fvoA-5h2gA:
undetectable		 5fvoA-5h2gA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N9X_A_THRA601_0
(ADENYLATION DOMAIN)		 5h2g DIAMINOPIMELATE
EPIMERASE
(Corynebacterium
glutamicum) 		4 / 7 PHE A 189
PHE A 188
GLY A 154
GLY A 152
 None
 0.98A 5n9xA-5h2gA:
undetectable		 5n9xA-5h2gA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5h2g DIAMINOPIMELATE
EPIMERASE
(Corynebacterium
glutamicum) 		3 / 3 MET A  33
ASP A  28
ARG A 110
 None
 1.16A 5z6kA-5h2gA:
undetectable		 5z6kA-5h2gA:
20.36