SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h34'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)		 5h34 METHIONINE-TRNA
LIGASE
(Nanoarchaeum
equitans) 		3 / 3 ASP A 681
PHE A 677
VAL A 775
 None
 0.66A 1kijB-5h34A:
undetectable		 1kijB-5h34A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_1
(HIV-1 PROTEASE)		 5h34 METHIONINE-TRNA
LIGASE
(Nanoarchaeum
equitans) 		5 / 12 LEU A 713
GLY A 716
VAL A 690
VAL A 704
ILE A 702
 None
 0.80A 3cywA-5h34A:
undetectable		 3cywA-5h34A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_2
(HIV-1 PROTEASE)		 5h34 METHIONINE-TRNA
LIGASE
(Nanoarchaeum
equitans) 		5 / 12 LEU A 713
GLY A 716
VAL A 690
VAL A 704
ILE A 702
 None
 0.91A 3cywB-5h34A:
undetectable		 3cywB-5h34A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 5h34 METHIONINE-TRNA
LIGASE
(Nanoarchaeum
equitans) 		5 / 12 LEU A 713
GLY A 716
VAL A 690
VAL A 704
ILE A 702
 None
 0.93A 3jvyB-5h34A:
undetectable		 3jvyB-5h34A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 5h34 METHIONINE-TRNA
LIGASE
(Nanoarchaeum
equitans) 		5 / 12 LEU A 713
GLY A 716
VAL A 690
VAL A 704
ILE A 702
 None
 0.94A 3lzsA-5h34A:
undetectable		 3lzsA-5h34A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 5h34 METHIONINE-TRNA
LIGASE
(Nanoarchaeum
equitans) 		3 / 3 LEU A 751
MET A 682
TYR A 730
 None
 0.82A 4p6xG-5h34A:
undetectable		 4p6xG-5h34A:
17.80