SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h36'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_G_AG2G7003_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 5h36 UNCHARACTERIZED
PROTEIN TRIC
(Rhodobacter
sphaeroides) 		4 / 6 LEU E  93
ASP E  96
GLY E 133
ILE E 146
 None
 0.76A 1mt1G-5h36E:
undetectable
1mt1J-5h36E:
undetectable		 1mt1G-5h36E:
13.04
1mt1J-5h36E:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5h36 UNCHARACTERIZED
PROTEIN TRIC
(Rhodobacter
sphaeroides) 		5 / 12 ILE E  16
GLY E  21
GLY E  39
LEU E  92
LEU E  23
 None
 1.10A 1rjdA-5h36E:
undetectable		 1rjdA-5h36E:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5h36 UNCHARACTERIZED
PROTEIN TRIC
(Rhodobacter
sphaeroides) 		5 / 12 ILE E  16
GLY E  21
GLY E  39
LEU E  92
LEU E  23
 None
 1.06A 1rjdB-5h36E:
undetectable		 1rjdB-5h36E:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5h36 UNCHARACTERIZED
PROTEIN TRIC
(Rhodobacter
sphaeroides) 		5 / 12 ILE E  16
GLY E  21
GLY E  39
LEU E  92
LEU E  23
 None
 1.04A 1rjdC-5h36E:
undetectable		 1rjdC-5h36E:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5h36 UNCHARACTERIZED
PROTEIN TRIC
(Rhodobacter
sphaeroides) 		5 / 12 GLY E  73
GLY E  43
GLY E  39
THR E  42
LEU E 135
 None
 1.07A 2oxtA-5h36E:
undetectable		 2oxtA-5h36E:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_E_AG2E671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 5h36 UNCHARACTERIZED
PROTEIN TRIC
(Rhodobacter
sphaeroides) 		4 / 7 ILE E 146
LEU E  93
ASP E  96
GLY E 133
 None
 0.75A 2qqcD-5h36E:
undetectable
2qqcE-5h36E:
undetectable		 2qqcD-5h36E:
20.09
2qqcE-5h36E:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 5h36 UNCHARACTERIZED
PROTEIN TRIC
(Rhodobacter
sphaeroides) 		5 / 12 GLY E  73
GLY E  43
GLY E  39
THR E  42
LEU E 135
 None
 1.16A 2wa2A-5h36E:
undetectable		 2wa2A-5h36E:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 5h36 UNCHARACTERIZED
PROTEIN TRIC
(Rhodobacter
sphaeroides) 		5 / 9 ALA E 184
GLY E 180
GLY E 178
LEU E 100
ALA E 104
 None
 0.98A 2z0yA-5h36E:
undetectable		 2z0yA-5h36E:
25.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 5h36 UNCHARACTERIZED
PROTEIN TRIC
(Rhodobacter
sphaeroides) 		5 / 12 GLY E 159
GLY E 180
PHE E 185
VAL E 164
ALA E 155
 None
 1.30A 3dh0A-5h36E:
undetectable		 3dh0A-5h36E:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 5h36 UNCHARACTERIZED
PROTEIN TRIC
(Rhodobacter
sphaeroides) 		4 / 7 ALA E 156
ALA E 108
ALA E 127
THR E 128
 None
None
PX4  E 301 ( 4.8A)
None
 0.85A 4du2A-5h36E:
undetectable		 4du2A-5h36E:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 5h36 UNCHARACTERIZED
PROTEIN TRIC
(Rhodobacter
sphaeroides) 		4 / 7 ALA E 156
ALA E 108
ALA E 127
THR E 128
 None
None
PX4  E 301 ( 4.8A)
None
 0.82A 4du2B-5h36E:
undetectable		 4du2B-5h36E:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5h36 UNCHARACTERIZED
PROTEIN TRIC
(Rhodobacter
sphaeroides) 		5 / 12 LEU E 192
SER E 101
ALA E 129
PHE E  17
VAL E  24
 None
 1.21A 4ib4A-5h36E:
undetectable		 4ib4A-5h36E:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 5h36 UNCHARACTERIZED
PROTEIN TRIC
(Rhodobacter
sphaeroides) 		5 / 12 ASP E 137
ALA E  22
GLY E 132
PHE E  17
GLY E  39
 None
 1.18A 4mmdB-5h36E:
undetectable		 4mmdB-5h36E:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 5h36 UNCHARACTERIZED
PROTEIN TRIC
(Rhodobacter
sphaeroides) 		5 / 9 ASP E 137
ALA E  22
GLY E 132
PHE E  17
GLY E  39
 None
 1.17A 4mmeA-5h36E:
undetectable		 4mmeA-5h36E:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 5h36 UNCHARACTERIZED
PROTEIN TRIC
(Rhodobacter
sphaeroides) 		5 / 12 GLY E  46
ILE E 120
ALA E 121
MET E 124
GLY E 125
 None
 0.76A 4r29D-5h36E:
1.3		 4r29D-5h36E:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 5h36 UNCHARACTERIZED
PROTEIN TRIC
(Rhodobacter
sphaeroides) 		5 / 12 GLY E  47
ILE E 120
ALA E 121
MET E 124
GLY E 125
 None
 0.83A 4r29D-5h36E:
1.3		 4r29D-5h36E:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_B_5D5B927_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 5h36 UNCHARACTERIZED
PROTEIN TRIC
(Rhodobacter
sphaeroides) 		5 / 12 ASP E 137
LEU E  92
PRO E  85
ILE E  84
VAL E  41
 None
 1.33A 5dlvB-5h36E:
undetectable		 5dlvB-5h36E:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5h36 UNCHARACTERIZED
PROTEIN TRIC
(Rhodobacter
sphaeroides) 		5 / 12 PHE E 163
VAL E 105
ALA E 129
ALA E 104
GLY E 125
 None
 1.35A 5tzoA-5h36E:
undetectable		 5tzoA-5h36E:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5h36 UNCHARACTERIZED
PROTEIN TRIC
(Rhodobacter
sphaeroides) 		5 / 12 PHE E 163
VAL E 105
ALA E 129
ALA E 104
GLY E 125
 None
 1.34A 5tzoC-5h36E:
undetectable		 5tzoC-5h36E:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 5h36 UNCHARACTERIZED
PROTEIN TRIC
(Rhodobacter
sphaeroides) 		4 / 4 ALA E 104
ALA E 129
ALA E 156
ALA E 184
 None
 0.81A 6gtqA-5h36E:
undetectable
6gtqB-5h36E:
undetectable		 6gtqA-5h36E:
24.22
6gtqB-5h36E:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 5h36 UNCHARACTERIZED
PROTEIN TRIC
(Rhodobacter
sphaeroides) 		4 / 4 ALA E 156
ALA E 184
ALA E 104
ALA E 129
 None
 0.81A 6gtqA-5h36E:
undetectable
6gtqB-5h36E:
undetectable		 6gtqA-5h36E:
24.22
6gtqB-5h36E:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 5h36 UNCHARACTERIZED
PROTEIN TRIC
(Rhodobacter
sphaeroides) 		4 / 7 ALA E  33
GLY E  34
LEU E  38
GLY E  73
 None
 0.75A 6nm4A-5h36E:
undetectable		 6nm4A-5h36E:
19.72