SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h3b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 5h3b UNCHARACTERIZED
PROTEIN HI_1552
(Haemophilus
influenzae) 		4 / 7 ALA A  26
TYR A 133
SER A  65
ALA A  18
 None
None
IPA  A 302 (-2.6A)
None
 0.97A 1k5qA-5h3bA:
undetectable
1k5qB-5h3bA:
undetectable		 1k5qA-5h3bA:
23.39
1k5qB-5h3bA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 5h3b UNCHARACTERIZED
PROTEIN HI_1552
(Haemophilus
influenzae) 		4 / 8 VAL A  70
TYR A  42
GLY A  67
LEU A  49
 None
 0.93A 1s1xA-5h3bA:
undetectable		 1s1xA-5h3bA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TD7_A_NFLA2001_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 5h3b UNCHARACTERIZED
PROTEIN HI_1552
(Haemophilus
influenzae) 		5 / 9 LEU A 151
ILE A  99
GLY A  19
TYR A  44
PHE A 178
 None
None
IPA  A 302 (-3.6A)
None
None
 1.19A 1td7A-5h3bA:
undetectable		 1td7A-5h3bA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 5h3b UNCHARACTERIZED
PROTEIN HI_1552
(Haemophilus
influenzae) 		4 / 4 GLY A  19
SER A  65
ILE A 123
HIS A 200
 IPA  A 302 (-3.6A)
IPA  A 302 (-2.6A)
IPA  A 302 ( 4.8A)
IPA  A 302 ( 4.6A)
 0.97A 1yajJ-5h3bA:
4.6		 1yajJ-5h3bA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 5h3b UNCHARACTERIZED
PROTEIN HI_1552
(Haemophilus
influenzae) 		4 / 4 GLY A  19
SER A  65
ILE A 177
HIS A 200
 IPA  A 302 (-3.6A)
IPA  A 302 (-2.6A)
IPA  A 302 ( 4.7A)
IPA  A 302 ( 4.6A)
 1.26A 1yajJ-5h3bA:
4.6		 1yajJ-5h3bA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 5h3b UNCHARACTERIZED
PROTEIN HI_1552
(Haemophilus
influenzae) 		4 / 8 GLY A  67
VAL A  70
LEU A 151
ARG A 139
 None
 1.05A 3bgdB-5h3bA:
undetectable		 3bgdB-5h3bA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 5h3b UNCHARACTERIZED
PROTEIN HI_1552
(Haemophilus
influenzae) 		4 / 8 TYR A 201
HIS A  29
TYR A  16
LEU A 212
 None
 1.33A 3uzzB-5h3bA:
undetectable		 3uzzB-5h3bA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5h3b UNCHARACTERIZED
PROTEIN HI_1552
(Haemophilus
influenzae) 		3 / 3 GLN A 185
THR A  89
ASN A 182
 None
 0.83A 3v4tE-5h3bA:
undetectable		 3v4tE-5h3bA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 5h3b UNCHARACTERIZED
PROTEIN HI_1552
(Haemophilus
influenzae) 		3 / 3 GLU A  72
TRP A 187
HIS A 165
 None
 0.95A 5xipA-5h3bA:
undetectable		 5xipA-5h3bA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA609_0
(ALPHA-AMYLASE)		 5h3b UNCHARACTERIZED
PROTEIN HI_1552
(Haemophilus
influenzae) 		4 / 7 GLY A  19
TRP A  20
MET A   1
TYR A  44
 IPA  A 302 (-3.6A)
None
None
None
 1.26A 6ag0A-5h3bA:
undetectable		 6ag0A-5h3bA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC609_0
(ALPHA-AMYLASE)		 5h3b UNCHARACTERIZED
PROTEIN HI_1552
(Haemophilus
influenzae) 		4 / 7 GLY A  19
TRP A  20
MET A   1
TYR A  44
 IPA  A 302 (-3.6A)
None
None
None
 1.25A 6ag0C-5h3bA:
undetectable		 6ag0C-5h3bA:
19.52