SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h3c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_G_BEZG513_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5h3c PROTEIN SUPPRESSOR
OF NPR1-1,
CONSTITUTIVE 1
(Arabidopsis
thaliana) 		4 / 5 PHE A  27
ARG A  33
ILE A  52
PRO A  25
 None
 1.31A 1oniG-5h3cA:
undetectable
1oniH-5h3cA:
undetectable		 1oniG-5h3cA:
23.60
1oniH-5h3cA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 5h3c PROTEIN SUPPRESSOR
OF NPR1-1,
CONSTITUTIVE 1
(Arabidopsis
thaliana) 		5 / 11 ILE A  77
LEU A 174
ILE A 171
VAL A  32
LEU A  37
 None
 1.11A 3a51A-5h3cA:
undetectable		 3a51A-5h3cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 5h3c PROTEIN SUPPRESSOR
OF NPR1-1,
CONSTITUTIVE 1
(Arabidopsis
thaliana) 		5 / 12 ILE A  77
LEU A 174
ILE A 171
VAL A  32
LEU A  37
 None
 1.12A 3a51D-5h3cA:
undetectable		 3a51D-5h3cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1C_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 5h3c PROTEIN SUPPRESSOR
OF NPR1-1,
CONSTITUTIVE 1
(Arabidopsis
thaliana) 		5 / 10 PHE A 113
ILE A  79
ILE A 171
LEU A 161
HIS A 114
 None
 1.16A 3o1cA-5h3cA:
undetectable		 3o1cA-5h3cA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 5h3c PROTEIN SUPPRESSOR
OF NPR1-1,
CONSTITUTIVE 1
(Arabidopsis
thaliana) 		5 / 10 PHE A 113
ILE A  79
ILE A 171
LEU A 161
HIS A 114
 None
 1.16A 3o1xA-5h3cA:
undetectable		 3o1xA-5h3cA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 5h3c PROTEIN SUPPRESSOR
OF NPR1-1,
CONSTITUTIVE 1
(Arabidopsis
thaliana) 		5 / 10 PHE A 113
ILE A 111
ILE A 171
LEU A 161
HIS A 114
 None
 1.28A 3o1xA-5h3cA:
undetectable		 3o1xA-5h3cA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 5h3c PROTEIN SUPPRESSOR
OF NPR1-1,
CONSTITUTIVE 1
(Arabidopsis
thaliana) 		5 / 10 PHE A 113
ILE A  79
ILE A 171
LEU A 161
HIS A 114
 None
 1.11A 3qgzA-5h3cA:
undetectable		 3qgzA-5h3cA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 5h3c PROTEIN SUPPRESSOR
OF NPR1-1,
CONSTITUTIVE 1
(Arabidopsis
thaliana) 		5 / 10 PHE A 113
ILE A 111
ILE A 171
LEU A 161
HIS A 114
 None
 1.25A 3qgzA-5h3cA:
undetectable		 3qgzA-5h3cA:
20.67