SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h3w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 5h3w FIBRONECTIN/FIBRINOG
EN BINDING PROTEIN
(Streptococcus
suis) 		4 / 4 THR A 117
LEU A 121
VAL A 124
LEU A 128
 None
 0.56A 1fbmB-5h3wA:
2.5		 1fbmB-5h3wA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 5h3w FIBRONECTIN/FIBRINOG
EN BINDING PROTEIN
(Streptococcus
suis) 		4 / 4 THR A 117
LEU A 121
VAL A 124
LEU A 128
 None
 0.66A 1mz9D-5h3wA:
2.8		 1mz9D-5h3wA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 5h3w FIBRONECTIN/FIBRINOG
EN BINDING PROTEIN
(Streptococcus
suis) 		5 / 12 ILE A 144
LEU A 143
LEU A  13
ASN A 180
PRO A 163
 None
 1.20A 3dcjA-5h3wA:
undetectable
3dcjB-5h3wA:
undetectable		 3dcjA-5h3wA:
20.21
3dcjB-5h3wA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 5h3w FIBRONECTIN/FIBRINOG
EN BINDING PROTEIN
(Streptococcus
suis) 		3 / 3 ARG A 151
ARG A 152
ILE A 157
 None
 0.90A 4b7qA-5h3wA:
undetectable		 4b7qA-5h3wA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 5h3w FIBRONECTIN/FIBRINOG
EN BINDING PROTEIN
(Streptococcus
suis) 		4 / 7 PRO A 217
VAL A 221
ALA A 225
PHE A 199
 None
 0.72A 4lb2A-5h3wA:
undetectable		 4lb2A-5h3wA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)		 5h3w FIBRONECTIN/FIBRINOG
EN BINDING PROTEIN
(Streptococcus
suis) 		3 / 3 SER A 123
MET A 127
ASP A 244
 None
 0.92A 4mm4B-5h3wA:
undetectable		 4mm4B-5h3wA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)		 5h3w FIBRONECTIN/FIBRINOG
EN BINDING PROTEIN
(Streptococcus
suis) 		3 / 3 ARG A  45
GLU A  39
TYR A  97
 None
 1.01A 4r29D-5h3wA:
undetectable		 4r29D-5h3wA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPE_A_SAMA2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)		 5h3w FIBRONECTIN/FIBRINOG
EN BINDING PROTEIN
(Streptococcus
suis) 		5 / 12 GLY A 206
ASP A 125
ASN A 181
LYS A 179
ILE A 139
 None
 1.04A 4ypeA-5h3wA:
undetectable		 4ypeA-5h3wA:
20.43