SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h42'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_0
(ALCOHOL
DEHYDROGENASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 11 LEU A 954
HIS A 926
LEU A 990
SER A 973
VAL A 958
 None
 1.23A 1ee2A-5h42A:
undetectable		 1ee2A-5h42A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_1
(ALCOHOL
DEHYDROGENASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 11 LEU A 954
HIS A 926
LEU A 990
SER A 973
VAL A 958
 None
 1.18A 1ee2B-5h42A:
undetectable		 1ee2B-5h42A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_1_T441128_1
(TRANSTHYRETIN)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 5 LEU A1019
GLU A 931
ALA A1017
LEU A1020
 None
 1.18A 1eta1-5h42A:
undetectable		 1eta1-5h42A:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		3 / 3 GLN A 144
ILE A 252
HIS A 248
 None
 0.70A 1fm9A-5h42A:
undetectable		 1fm9A-5h42A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 8 GLN A  41
ASN A  43
LEU A 533
SER A 383
 None
 0.95A 1hk3A-5h42A:
undetectable		 1hk3A-5h42A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_A_T44A128_1
(TRANSTHYRETIN)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 10 LEU A 220
GLU A 620
LYS A 199
LEU A 196
GLU A 332
 None
 1.30A 1ie4A-5h42A:
1.4
1ie4C-5h42A:
0.7		 1ie4A-5h42A:
8.14
1ie4C-5h42A:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J3J_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 10 ILE A 862
ALA A 780
ASN A 874
ILE A 878
ILE A 861
 None
 1.30A 1j3jA-5h42A:
undetectable		 1j3jA-5h42A:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		3 / 3 GLN A 144
ILE A 252
HIS A 248
 None
 0.70A 1k74A-5h42A:
undetectable		 1k74A-5h42A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_A_DOLA300_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 11 ILE A 877
HIS A 926
LEU A 933
LEU A 854
ASP A 944
 None
 1.02A 1mrlA-5h42A:
undetectable
1mrlB-5h42A:
undetectable		 1mrlA-5h42A:
10.96
1mrlB-5h42A:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 6 LEU A 449
VAL A 448
ILE A 447
TYR A 427
 None
 0.87A 1s9qA-5h42A:
undetectable		 1s9qA-5h42A:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAK_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		6 / 12 GLY A  69
ILE A 529
LEU A  22
GLY A  25
GLY A  24
PRO A  23
 None
 1.46A 1uakA-5h42A:
undetectable		 1uakA-5h42A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_0
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 LEU A1044
LEU A1098
VAL A1053
PHE A1055
ILE A1031
 None
 1.49A 1uobA-5h42A:
undetectable		 1uobA-5h42A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 THR A 515
LEU A 516
ILE A 536
VAL A 463
LEU A 480
 None
 1.34A 1wsvA-5h42A:
undetectable		 1wsvA-5h42A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 THR A 515
LEU A 516
ILE A 536
VAL A 463
LEU A 480
 None
 1.34A 1wsvB-5h42A:
undetectable		 1wsvB-5h42A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 7 ASN A1080
ARG A1086
HIS A1066
VAL A1069
 None
 1.15A 1wu8A-5h42A:
undetectable
1wu8C-5h42A:
undetectable		 1wu8A-5h42A:
12.91
1wu8C-5h42A:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 HIS A 148
ASP A 189
LEU A 220
ILE A 127
MET A  36
 None
 1.37A 1xoqA-5h42A:
undetectable		 1xoqA-5h42A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 HIS A 148
ASP A 189
LEU A 220
ILE A 127
MET A  36
 None
 1.34A 1xoqB-5h42A:
undetectable		 1xoqB-5h42A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ1_A_HLTA2001_1
(FERRITIN LIGHT CHAIN)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 4 LEU A 196
SER A 197
TYR A 198
LEU A 389
 None
 1.16A 1xz1A-5h42A:
2.5		 1xz1A-5h42A:
10.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ3_A_ICFA201_1
(FERRITIN LIGHT CHAIN)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 4 LEU A 196
SER A 197
TYR A 198
LEU A 389
 None
 1.17A 1xz3A-5h42A:
2.3		 1xz3A-5h42A:
10.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_1
(POL POLYPROTEIN)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 9 LEU A 146
GLY A 242
ILE A 243
VAL A 129
ILE A 127
 None
 1.04A 2avoA-5h42A:
undetectable		 2avoA-5h42A:
7.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 PHE A1107
ALA A1100
ASN A1073
ILE A1090
ILE A1067
 None
 1.12A 2bjfA-5h42A:
undetectable		 2bjfA-5h42A:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BLA_A_CP6A302_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 11 ILE A 862
ALA A 780
ASN A 874
ILE A 878
ILE A 861
 None
 1.22A 2blaA-5h42A:
undetectable		 2blaA-5h42A:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH8_A_VIBA1_1
(MAJOR PRION PROTEIN)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 6 HIS A 148
ASP A 978
ASP A 979
TYR A 897
 None
 1.05A 2lh8A-5h42A:
undetectable		 2lh8A-5h42A:
6.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB502_1
(CYTOCHROME P450 2C8)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 10 SER A 860
ILE A 861
LEU A 875
VAL A 888
ILE A 877
 None
 1.18A 2nnhB-5h42A:
undetectable		 2nnhB-5h42A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 5 ILE A 850
LEU A 841
ASP A 759
ALA A 895
 None
None
G1P  A1201 (-4.5A)
None
 1.01A 2opxA-5h42A:
undetectable		 2opxA-5h42A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUB_A_2TNA134_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 4 LEU A 933
ILE A 861
HIS A 926
LYS A 941
 None
 0.86A 2oubA-5h42A:
0.0		 2oubA-5h42A:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 11 LEU A  52
GLN A 226
ILE A 110
PHE A 238
LEU A 112
 None
 1.21A 2q6hA-5h42A:
undetectable		 2q6hA-5h42A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 11 LEU A  52
GLN A 226
ILE A 110
PHE A 238
LEU A 112
 None
 1.21A 2qeiA-5h42A:
undetectable		 2qeiA-5h42A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 LEU A 855
ALA A 925
THR A 761
HIS A 684
ARG A 630
 None
None
None
None
G1P  A1201 (-3.9A)
 1.31A 2qo4A-5h42A:
1.7		 2qo4A-5h42A:
8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_CHDA332_0
(CHOLOYLGLYCINE
HYDROLASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 PHE A1107
ALA A1100
ASN A1073
ILE A1090
ILE A1067
 None
 1.08A 2rlcA-5h42A:
undetectable		 2rlcA-5h42A:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		3 / 3 SER A 395
THR A 464
PHE A 523
 None
 0.57A 2x91A-5h42A:
3.4		 2x91A-5h42A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN7_A_T44A1355_1
(THYROXINE-BINDING
GLOBULIN)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 10 LEU A 516
LEU A 534
SER A 490
LEU A 489
ARG A 482
 None
 1.12A 2xn7A-5h42A:
undetectable
2xn7B-5h42A:
undetectable		 2xn7A-5h42A:
15.81
2xn7B-5h42A:
2.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 6 GLN A 370
PHE A 371
PHE A 506
LEU A 504
 None
 1.15A 3ablP-5h42A:
3.3
3ablW-5h42A:
undetectable		 3ablP-5h42A:
12.60
3ablW-5h42A:
5.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 5 ILE A 927
HIS A 924
ARG A1013
GLY A 635
 None
 1.26A 3b9mA-5h42A:
3.5		 3b9mA-5h42A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 5 ILE A 927
HIS A 924
ARG A1013
GLY A1009
 None
 1.09A 3b9mA-5h42A:
3.5		 3b9mA-5h42A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_0
(N,N-DIMETHYLTRANSFER
ASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		6 / 12 ALA A 749
LEU A 745
SER A 746
SER A 814
TYR A 818
LEU A 819
 None
 1.31A 3bxoA-5h42A:
undetectable		 3bxoA-5h42A:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DGQ_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 5 ARG A 743
ILE A 751
TYR A 744
THR A 748
 None
 1.22A 3dgqA-5h42A:
undetectable		 3dgqA-5h42A:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 GLY A  42
ASN A  38
ASP A 126
GLN A 409
LEU A  22
 None
 1.14A 3eeyH-5h42A:
undetectable		 3eeyH-5h42A:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 GLY A  42
ASN A  38
ASP A 126
GLN A 409
LEU A  22
 None
 1.12A 3eeyI-5h42A:
undetectable		 3eeyI-5h42A:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 6 ILE A 652
TYR A 698
ILE A 654
HIS A 659
 None
 1.05A 3eteA-5h42A:
undetectable
3eteE-5h42A:
undetectable		 3eteA-5h42A:
19.43
3eteE-5h42A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 5 ILE A 652
TYR A 698
ILE A 654
HIS A 659
 None
 1.03A 3eteB-5h42A:
undetectable
3eteC-5h42A:
undetectable		 3eteB-5h42A:
19.43
3eteC-5h42A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 7 ILE A 654
HIS A 659
ILE A 652
TYR A 698
 None
 1.03A 3eteD-5h42A:
undetectable
3eteF-5h42A:
undetectable		 3eteD-5h42A:
19.43
3eteF-5h42A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 HIS A 148
ASP A 189
LEU A 220
ILE A 127
MET A  36
 None
 1.38A 3g4lC-5h42A:
undetectable		 3g4lC-5h42A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 GLY A 899
TYR A 123
ASN A 164
SER A 161
GLY A 147
 None
 0.97A 3hs6B-5h42A:
undetectable		 3hs6B-5h42A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		3 / 3 GLU A 662
ASP A 713
ASP A 719
 None
 0.65A 3jb2A-5h42A:
undetectable		 3jb2A-5h42A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_F_LFXF0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 5 ARG A 398
ARG A 386
GLY A 387
GLU A 139
 None
 1.28A 3k9fA-5h42A:
undetectable
3k9fB-5h42A:
undetectable
3k9fC-5h42A:
undetectable		 3k9fA-5h42A:
18.44
3k9fB-5h42A:
18.44
3k9fC-5h42A:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_2
(GENOME POLYPROTEIN)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 4 GLN A 354
PHE A 673
TYR A 676
VAL A 712
 None
 1.40A 3keeA-5h42A:
0.0		 3keeA-5h42A:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 7 GLN A 392
SER A  48
LEU A 207
ILE A 391
 None
 0.95A 3ln1C-5h42A:
undetectable		 3ln1C-5h42A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N0H_A_TOPA187_1
(DIHYDROFOLATE
REDUCTASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 11 ILE A 538
PHE A 544
ILE A 436
LEU A 449
VAL A 463
 None
 1.09A 3n0hA-5h42A:
undetectable		 3n0hA-5h42A:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 ARG A 743
LEU A 773
LEU A 745
GLY A 755
ALA A 754
 None
 0.86A 3n8xB-5h42A:
undetectable		 3n8xB-5h42A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 ARG A 743
LEU A 773
LEU A 745
GLY A 755
ALA A 754
 None
 0.90A 3n8zA-5h42A:
3.2		 3n8zA-5h42A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 LEU A 890
ILE A 918
ALA A 895
ILE A 904
ALA A 765
 None
 1.16A 3nxuB-5h42A:
undetectable		 3nxuB-5h42A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 LEU A 225
TYR A 157
GLY A 153
GLY A 177
SER A 178
 None
 1.03A 3ou6A-5h42A:
undetectable		 3ou6A-5h42A:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 LEU A 225
TYR A 157
GLY A 153
GLY A 177
SER A 178
 None
 1.04A 3ou6B-5h42A:
undetectable		 3ou6B-5h42A:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 LEU A 225
TYR A 157
GLY A 153
GLY A 177
SER A 178
 None
 1.04A 3ou7A-5h42A:
undetectable		 3ou7A-5h42A:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 LEU A 225
TYR A 157
GLY A 153
GLY A 177
SER A 178
 None
 1.04A 3ou7D-5h42A:
undetectable		 3ou7D-5h42A:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_B_FLPB701_1
(CYCLOOXYGENASE-2)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 11 ARG A 743
LEU A 773
LEU A 745
GLY A 755
ALA A 754
 None
 0.89A 3pghB-5h42A:
0.4		 3pghB-5h42A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_D_FLPD701_1
(CYCLOOXYGENASE-2)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 ARG A 743
LEU A 773
LEU A 745
GLY A 755
ALA A 754
 None
 0.88A 3pghD-5h42A:
undetectable		 3pghD-5h42A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA187_1
(DIHYDROFOLATE
REDUCTASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 ILE A 538
PHE A 544
ILE A 436
LEU A 449
VAL A 463
 None
 1.10A 3s3vA-5h42A:
undetectable		 3s3vA-5h42A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 8 PRO A 172
HIS A  32
ILE A  35
SER A  34
 None
 1.11A 3sfeB-5h42A:
undetectable
3sfeC-5h42A:
undetectable		 3sfeB-5h42A:
11.87
3sfeC-5h42A:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UY4_A_PAUA302_0
(PANTOTHENATE
SYNTHETASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 8 HIS A1066
VAL A1111
VAL A1059
ASP A1032
 None
 0.97A 3uy4A-5h42A:
undetectable		 3uy4A-5h42A:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 TYR A 565
LEU A 343
HIS A 607
LEU A1003
ALA A 600
 None
 1.03A 3vw7A-5h42A:
undetectable		 3vw7A-5h42A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 4 PRO A 856
LEU A 857
ILE A 877
ARG A 873
 None
 1.15A 3w1wA-5h42A:
undetectable		 3w1wA-5h42A:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOF_A_HQEA200_1
(FLAVOREDOXIN)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 5 TYR A1057
VAL A1035
ARG A1086
HIS A1066
 None
 1.24A 3zofA-5h42A:
0.0		 3zofA-5h42A:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOF_B_HQEB200_1
(FLAVOREDOXIN)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 5 TYR A1057
VAL A1035
ARG A1086
HIS A1066
 None
 1.21A 3zofB-5h42A:
0.0		 3zofB-5h42A:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_A_NCAA1359_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 7 THR A 101
HIS A  32
ASN A  16
TYR A 267
 None
 1.45A 4a3uA-5h42A:
undetectable		 4a3uA-5h42A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_NCAB1359_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 7 THR A 101
HIS A  32
ASN A  16
TYR A 267
 None
 1.46A 4a3uB-5h42A:
undetectable		 4a3uB-5h42A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		3 / 3 ARG A 907
ASP A 631
GLN A 634
 None
G1P  A1201 (-2.8A)
None
 0.75A 4azsA-5h42A:
undetectable		 4azsA-5h42A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 ALA A 717
PHE A 665
ARG A 735
GLU A 727
LEU A 721
 None
 1.26A 4azwA-5h42A:
undetectable		 4azwA-5h42A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_1
(ASPARTYL PROTEASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 11 LEU A 146
GLY A 242
ILE A 243
VAL A 129
ILE A 127
 None
 0.97A 4dqeA-5h42A:
undetectable		 4dqeA-5h42A:
6.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_1
(WILD-TYPE HIV-1
PROTEASE DIMER)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 11 LEU A 146
GLY A 242
ILE A 243
VAL A 129
ILE A 127
 None
 0.94A 4dqhA-5h42A:
undetectable		 4dqhA-5h42A:
6.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EVR_A_BEZA401_0
(PUTATIVE ABC
TRANSPORTER SUBUNIT,
SUBSTRATE-BINDING
COMPONENT)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 11 LEU A 750
VAL A 774
TYR A 839
ALA A 826
PHE A 815
 None
 1.25A 4evrA-5h42A:
undetectable		 4evrA-5h42A:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 4 PRO A 856
LEU A 857
ILE A 877
ARG A 873
 None
 1.18A 4f4dA-5h42A:
undetectable		 4f4dA-5h42A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 ARG A 916
GLU A 917
GLY A 915
TYR A 969
SER A1005
 G1P  A1201 ( 4.0A)
G1P  A1201 (-3.6A)
None
None
G1P  A1201 (-2.5A)
 1.23A 4ffwA-5h42A:
undetectable		 4ffwA-5h42A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 ARG A 916
GLU A 917
GLY A 915
TYR A 969
SER A1005
 G1P  A1201 ( 4.0A)
G1P  A1201 (-3.6A)
None
None
G1P  A1201 (-2.5A)
 1.29A 4ffwB-5h42A:
undetectable		 4ffwB-5h42A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		3 / 3 GLN A 370
THR A 376
THR A 377
 None
 0.79A 4fu9A-5h42A:
undetectable		 4fu9A-5h42A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		3 / 3 GLN A 370
THR A 376
THR A 377
 None
 0.78A 4fufA-5h42A:
undetectable		 4fufA-5h42A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_1
(MEMBRANE LIPOPROTEIN
TPN38(B))		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 SER A1005
GLN A 921
ILE A 601
GLY A1007
ASP A 608
 G1P  A1201 (-2.5A)
None
None
None
None
 0.96A 4iilA-5h42A:
undetectable		 4iilA-5h42A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 8 ASN A 950
PRO A 951
GLN A 921
ILE A 927
 None
 1.07A 4iilA-5h42A:
undetectable		 4iilA-5h42A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		3 / 3 TRP A 627
GLN A 680
THR A 629
 None
 0.98A 4m2xA-5h42A:
undetectable		 4m2xA-5h42A:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		3 / 3 TRP A 690
GLN A 680
THR A 629
 None
 0.95A 4m2xA-5h42A:
undetectable		 4m2xA-5h42A:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		3 / 3 GLY A  24
PRO A  23
ALA A   8
 None
 0.48A 4qn9B-5h42A:
undetectable		 4qn9B-5h42A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA207_0
(OXIDOREDUCTASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 4 GLU A 638
GLY A 635
HIS A 924
ARG A 928
 None
 1.43A 4r82A-5h42A:
undetectable
4r82B-5h42A:
undetectable		 4r82A-5h42A:
10.28
4r82B-5h42A:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_A_SAMA1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 GLY A 470
TYR A 474
SER A 490
ASN A 379
TYR A 676
 None
 1.44A 4ymgA-5h42A:
undetectable		 4ymgA-5h42A:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 11 MET A 508
LEU A 487
LEU A   3
HIS A 465
LEU A 467
 None
 1.18A 4zn7B-5h42A:
undetectable		 4zn7B-5h42A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 6 LYS A  73
GLY A  24
GLY A  25
ASP A  26
 None
 0.88A 5a06D-5h42A:
undetectable		 5a06D-5h42A:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		3 / 3 THR A1052
THR A1047
PHE A 583
 None
 0.92A 5cxvA-5h42A:
undetectable		 5cxvA-5h42A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		3 / 3 THR A 377
ALA A 625
ASN A 375
 None
 0.59A 5ersA-5h42A:
undetectable		 5ersA-5h42A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_2
(CDL2.3B)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 9 ILE A 862
MET A 936
VAL A 888
ILE A 878
LEU A 781
 None
 1.36A 5iepA-5h42A:
undetectable		 5iepA-5h42A:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 ARG A 743
LEU A 773
LEU A 745
GLY A 755
ALA A 754
 None
 1.01A 5ikrB-5h42A:
undetectable		 5ikrB-5h42A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 6 LEU A 804
SER A 805
ILE A 793
PHE A 800
 None
 1.02A 5jw1A-5h42A:
undetectable		 5jw1A-5h42A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA407_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 5 ASP A 189
THR A 191
GLN A 192
GLU A 336
 None
 1.46A 5k9dA-5h42A:
undetectable		 5k9dA-5h42A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_B_BEZB301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 8 ILE A 478
LEU A 489
MET A 508
LEU A 487
 None
 1.02A 5u4sB-5h42A:
undetectable		 5u4sB-5h42A:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 LEU A 890
ILE A 918
ALA A 895
ILE A 904
ALA A 765
 None
 1.16A 5vc0A-5h42A:
undetectable		 5vc0A-5h42A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_1
(CYTOCHROME P450 3A5)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 ARG A 398
SER A 535
ILE A 521
PHE A 523
GLY A  47
 None
 1.12A 5veuA-5h42A:
undetectable		 5veuA-5h42A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		3 / 3 GLN A 144
ILE A 252
HIS A 248
 None
 0.68A 5z12B-5h42A:
undetectable		 5z12B-5h42A:
6.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		3 / 3 GLU A 917
LEU A 890
ARG A 853
 G1P  A1201 (-3.6A)
None
None
 0.71A 6d8fA-5h42A:
undetectable		 6d8fA-5h42A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		3 / 3 PHE A 193
ARG A  55
ALA A 185
 None
 0.97A 6ecfB-5h42A:
undetectable		 6ecfB-5h42A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 5 LEU A   6
TYR A 474
ILE A 399
GLY A  42
 None
 1.05A 6hd6A-5h42A:
undetectable		 6hd6A-5h42A:
5.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_E_PCFE202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 8 TYR A 714
ALA A 736
VAL A 737
ARG A 735
 None
 1.06A 6hu9a-5h42A:
undetectable
6hu9e-5h42A:
undetectable		 6hu9a-5h42A:
19.19
6hu9e-5h42A:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_N_PCFN606_0
(CYTOCHROME B)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		5 / 12 PHE A 613
ALA A 609
TYR A 605
TYR A 969
TYR A 575
 None
 1.25A 6hu9N-5h42A:
undetectable		 6hu9N-5h42A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 5h42 UNCHARACTERIZED
PROTEIN
(Lachnoclostridiu
m
phytofermentans) 		4 / 8 ASN A 599
PHE A 583
VAL A1042
TYR A1057
 None
 1.12A 6huoC-5h42A:
2.5
6huoD-5h42A:
2.5		 6huoC-5h42A:
5.66
6huoD-5h42A:
5.90