SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h4b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5h4b CEREBELLIN-4
(Mus
musculus) 		4 / 7 PHE A 115
ALA A 140
ILE A  84
ILE A 126
 None
 0.94A 1oniD-5h4bA:
undetectable
1oniF-5h4bA:
undetectable		 1oniD-5h4bA:
23.43
1oniF-5h4bA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 5h4b CEREBELLIN-4
(Mus
musculus) 		5 / 12 GLY A 143
ALA A 142
VAL A 117
GLY A 173
VAL A 120
 None
 0.98A 3lzsA-5h4bA:
undetectable		 3lzsA-5h4bA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 5h4b CEREBELLIN-4
(Mus
musculus) 		5 / 12 GLY A 143
ALA A 142
VAL A 117
GLY A 173
VAL A 120
 None
 0.98A 3lzsB-5h4bA:
undetectable		 3lzsB-5h4bA:
19.02