SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h4r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		4 / 6 ASN A 362
PHE A 372
ALA A 364
GLY A 369
 CTT  A 401 (-4.0A)
CTT  A 401 ( 4.5A)
None
None
 1.07A 1c8lA-5h4rA:
undetectable		 1c8lA-5h4rA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		3 / 3 SER A 297
GLU A 298
GLU A 299
 None
 0.50A 1eqbD-5h4rA:
undetectable		 1eqbD-5h4rA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		3 / 3 SER A 297
GLU A 298
GLU A 299
 None
 0.50A 1eqbB-5h4rA:
undetectable		 1eqbB-5h4rA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		4 / 6 ASN A 362
PHE A 372
ALA A 364
GLY A 369
 CTT  A 401 (-4.0A)
CTT  A 401 ( 4.5A)
None
None
 1.09A 1gfzA-5h4rA:
undetectable		 1gfzA-5h4rA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		3 / 3 ALA A  59
VAL A 101
TRP A 118
 None
 0.72A 1jnoA-5h4rA:
undetectable		 1jnoA-5h4rA:
3.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		3 / 3 ALA A  59
VAL A 101
TRP A 118
 None
 0.72A 1jnoB-5h4rA:
undetectable		 1jnoB-5h4rA:
3.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		3 / 3 ALA A  59
VAL A 101
TRP A 118
 None
 0.89A 1jo3A-5h4rA:
undetectable		 1jo3A-5h4rA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		3 / 3 ALA A  59
VAL A 101
TRP A 118
 None
 0.89A 1jo3B-5h4rA:
undetectable		 1jo3B-5h4rA:
4.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		3 / 3 ALA A  59
VAL A 101
TRP A 118
 None
 0.87A 1jo4A-5h4rA:
undetectable		 1jo4A-5h4rA:
3.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		3 / 3 ALA A  59
VAL A 101
TRP A 118
 None
 0.87A 1jo4B-5h4rA:
undetectable		 1jo4B-5h4rA:
3.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		4 / 6 ASN A 362
PHE A 372
ALA A 364
GLY A 369
 CTT  A 401 (-4.0A)
CTT  A 401 ( 4.5A)
None
None
 1.08A 1l5qA-5h4rA:
undetectable		 1l5qA-5h4rA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		4 / 6 ASN A 362
PHE A 372
ALA A 364
GLY A 369
 CTT  A 401 (-4.0A)
CTT  A 401 ( 4.5A)
None
None
 1.09A 1l5qB-5h4rA:
undetectable		 1l5qB-5h4rA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		4 / 6 ASN A 362
PHE A 372
ALA A 364
GLY A 369
 CTT  A 401 (-4.0A)
CTT  A 401 ( 4.5A)
None
None
 1.06A 1l7xA-5h4rA:
undetectable		 1l7xA-5h4rA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		4 / 6 ASN A 362
PHE A 372
ALA A 364
GLY A 369
 CTT  A 401 (-4.0A)
CTT  A 401 ( 4.5A)
None
None
 1.11A 1l7xB-5h4rA:
undetectable		 1l7xB-5h4rA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		3 / 3 ALA A  59
VAL A 101
TRP A 118
 None
 0.76A 1magA-5h4rA:
undetectable		 1magA-5h4rA:
3.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		3 / 3 ALA A  59
VAL A 101
TRP A 118
 None
 0.75A 1magB-5h4rA:
undetectable		 1magB-5h4rA:
3.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		3 / 3 ALA A  59
VAL A 101
TRP A 118
 None
 0.73A 1ng8A-5h4rA:
undetectable		 1ng8A-5h4rA:
3.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		3 / 3 ALA A  59
VAL A 101
TRP A 118
 None
 0.73A 1ng8B-5h4rA:
undetectable		 1ng8B-5h4rA:
3.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		3 / 3 ALA A  59
VAL A 101
TRP A 118
 None
 0.81A 1nruA-5h4rA:
undetectable		 1nruA-5h4rA:
3.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		3 / 3 ALA A  59
VAL A 101
TRP A 118
 None
 0.81A 1nruB-5h4rA:
undetectable		 1nruB-5h4rA:
3.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		5 / 11 ILE A 166
VAL A 170
ALA A 171
PHE A 174
LEU A 181
 None
 0.67A 1uduA-5h4rA:
undetectable		 1uduA-5h4rA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_B_CIAB2003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		5 / 12 ILE A 166
VAL A 170
ALA A 171
PHE A 174
LEU A 181
 None
 0.68A 1uduB-5h4rA:
undetectable		 1uduB-5h4rA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		4 / 6 ILE A 387
VAL A  44
ILE A 137
ILE A 268
 None
 0.81A 1uwhA-5h4rA:
undetectable		 1uwhA-5h4rA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQY_A_ADNA400_1
(MEMBRANE LIPOPROTEIN
TMPC)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		5 / 12 ASN A  52
GLY A  50
MET A 391
PHE A 327
GLY A 328
 None
 1.08A 2fqyA-5h4rA:
undetectable		 2fqyA-5h4rA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		4 / 5 ASN A 362
PHE A 372
ALA A 364
GLY A 369
 CTT  A 401 (-4.0A)
CTT  A 401 ( 4.5A)
None
None
 1.10A 3bcrA-5h4rA:
undetectable		 3bcrA-5h4rA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		4 / 6 ASN A 362
PHE A 372
ALA A 364
GLY A 369
 CTT  A 401 (-4.0A)
CTT  A 401 ( 4.5A)
None
None
 1.11A 3dd1A-5h4rA:
undetectable		 3dd1A-5h4rA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		4 / 6 ASN A 362
PHE A 372
ALA A 364
GLY A 369
 CTT  A 401 (-4.0A)
CTT  A 401 ( 4.5A)
None
None
 1.06A 3dd1B-5h4rA:
undetectable		 3dd1B-5h4rA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		4 / 6 ASN A 362
PHE A 372
ALA A 364
GLY A 369
 CTT  A 401 (-4.0A)
CTT  A 401 ( 4.5A)
None
None
 1.09A 3ddsA-5h4rA:
undetectable		 3ddsA-5h4rA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		4 / 6 ASN A 362
PHE A 372
ALA A 364
GLY A 369
 CTT  A 401 (-4.0A)
CTT  A 401 ( 4.5A)
None
None
 1.07A 3ddsB-5h4rA:
undetectable		 3ddsB-5h4rA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		4 / 6 ASN A 362
PHE A 372
ALA A 364
GLY A 369
 CTT  A 401 (-4.0A)
CTT  A 401 ( 4.5A)
None
None
 1.08A 3ddwA-5h4rA:
undetectable		 3ddwA-5h4rA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		4 / 6 ASN A 362
PHE A 372
ALA A 364
GLY A 369
 CTT  A 401 (-4.0A)
CTT  A 401 ( 4.5A)
None
None
 1.08A 3ddwB-5h4rA:
undetectable		 3ddwB-5h4rA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGG_A_CHDA211_0
(CMER)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		4 / 7 CYH A 357
PHE A 307
PHE A 327
TYR A 274
 None
None
None
CTT  A 401 ( 3.6A)
 1.40A 3hggA-5h4rA:
0.8		 3hggA-5h4rA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		4 / 7 PHE A  43
ILE A 182
SER A 234
ARG A 226
 None
 0.92A 3pglA-5h4rA:
1.8		 3pglA-5h4rA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		4 / 7 SER A  32
VAL A 316
ILE A  35
TYR A 346
 None
 0.99A 3tneB-5h4rA:
undetectable		 3tneB-5h4rA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		5 / 12 ARG A  98
GLU A 184
TYR A 274
ASN A 187
HIS A 141
 None
None
CTT  A 401 ( 3.6A)
CTT  A 401 (-2.7A)
CTT  A 401 (-3.9A)
 1.49A 3w2tB-5h4rA:
undetectable		 3w2tB-5h4rA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		4 / 5 GLU A 386
ARG A  22
PRO A 385
SER A 389
 None
 1.31A 4k17B-5h4rA:
undetectable		 4k17B-5h4rA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		4 / 6 ARG A 353
ARG A 301
ASP A 305
VAL A 347
 None
 1.38A 4xqeA-5h4rA:
undetectable		 4xqeA-5h4rA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		3 / 3 TRP A 199
MET A 202
ASN A 203
 None
 1.46A 5uc1A-5h4rA:
undetectable		 5uc1A-5h4rA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
RNA POLYMERASE SIGMA
FACTOR SIGA)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		4 / 4 LEU A 119
ASP A 120
GLN A 123
VAL A 220
 None
 1.11A 6bzoF-5h4rA:
undetectable		 6bzoF-5h4rA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 5h4r BETA-1,3-1,4-GLUCANA
SE
(Caldicellulosiru
ptor
sp.
F32) 		5 / 11 PHE A 307
LEU A 311
ILE A 304
ILE A 324
ILE A 355
 None
 1.08A 6gp2B-5h4rA:
undetectable		 6gp2B-5h4rA:
10.85