SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h55'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5h55 MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Kluyveromyces
lactis) 		4 / 8 PHE A 217
LEU A  40
ALA A 106
VAL A 122
 None
 0.83A 1epbB-5h55A:
undetectable		 1epbB-5h55A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5h55 MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Kluyveromyces
lactis) 		4 / 7 PRO A 166
LEU A 136
ALA A 138
PHE A  66
 None
 1.05A 2vcvA-5h55A:
undetectable		 2vcvA-5h55A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5h55 MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Kluyveromyces
lactis) 		4 / 7 PRO A 166
LEU A 136
ALA A 138
PHE A  66
 None
 1.05A 2vcvL-5h55A:
undetectable		 2vcvL-5h55A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_B_0LIB2_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5h55 MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Kluyveromyces
lactis) 		4 / 7 LEU A 134
VAL A  16
ILE A 146
ARG A  11
 None
 1.27A 3ik3B-5h55A:
undetectable		 3ik3B-5h55A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 5h55 MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Kluyveromyces
lactis) 		5 / 12 SER A 147
LEU A 136
PHE A 171
ALA A 176
LEU A 162
 None
 1.18A 4j7xB-5h55A:
undetectable		 4j7xB-5h55A:
25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 5h55 MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Kluyveromyces
lactis) 		4 / 5 LYS A  57
LEU A  91
GLU A  93
LEU A 134
 None
 1.22A 4k4yA-5h55A:
undetectable		 4k4yA-5h55A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 5h55 MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Kluyveromyces
lactis) 		4 / 4 LYS A  57
LEU A  91
GLU A  93
LEU A 134
 None
 1.23A 4k4yE-5h55A:
undetectable		 4k4yE-5h55A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 5h55 MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Kluyveromyces
lactis) 		4 / 5 LYS A  57
LEU A  91
GLU A  93
LEU A 134
 None
 1.23A 4k4yI-5h55A:
undetectable		 4k4yI-5h55A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5h55 MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Kluyveromyces
lactis) 		4 / 7 ARG A  11
ILE A  10
PRO A  51
ASP A  99
 None
 1.02A 4z4eA-5h55A:
undetectable		 4z4eA-5h55A:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5h55 MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Kluyveromyces
lactis) 		4 / 6 LYS A  41
LEU A  28
LEU A 216
PHE A 212
 None
 1.11A 5w97C-5h55A:
undetectable
5w97J-5h55A:
undetectable		 5w97C-5h55A:
20.86
5w97J-5h55A:
14.34