SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h5c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5h5c MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Kluyveromyces
lactis) 		4 / 7 ILE A 126
PRO A  52
GLY A  48
MET A  50
 None
 1.23A 2pnjB-5h5cA:
undetectable		 2pnjB-5h5cA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5h5c MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Kluyveromyces
lactis) 		4 / 7 MET A 131
PRO A  52
GLY A  48
MET A  50
 None
 1.17A 2pnjB-5h5cA:
undetectable		 2pnjB-5h5cA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA2_0
(FERROCHELATASE)		 5h5c MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Kluyveromyces
lactis) 		4 / 6 MET A 131
PRO A  52
GLY A  48
MET A  50
 None
 1.20A 3aqiA-5h5cA:
undetectable		 3aqiA-5h5cA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB4_0
(FERROCHELATASE)		 5h5c MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Kluyveromyces
lactis) 		4 / 6 MET A 131
PRO A  52
GLY A  48
MET A  50
 None
 1.24A 3aqiB-5h5cA:
undetectable		 3aqiB-5h5cA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_B_0LIB2_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5h5c MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Kluyveromyces
lactis) 		4 / 7 LEU A 134
VAL A  16
ILE A 146
ARG A  11
 None
 1.28A 3ik3B-5h5cA:
undetectable		 3ik3B-5h5cA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5h5c MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Kluyveromyces
lactis) 		4 / 7 ARG A  11
ILE A  10
PRO A  51
ASP A  99
 None
 0.99A 4w5oA-5h5cA:
undetectable		 4w5oA-5h5cA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5h5c MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Kluyveromyces
lactis) 		4 / 7 ARG A  11
ILE A  10
PRO A  51
ASP A  99
 None
 1.02A 4z4eA-5h5cA:
undetectable		 4z4eA-5h5cA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5h5c MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Kluyveromyces
lactis) 		4 / 7 ARG A  11
ILE A  10
PRO A  51
ASP A  99
 None
 0.96A 4z4gA-5h5cA:
undetectable		 4z4gA-5h5cA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 5h5c MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Kluyveromyces
lactis) 		4 / 8 VAL A  92
LEU A  90
ILE A   5
VAL A   3
 None
 0.83A 5nujA-5h5cA:
2.0		 5nujA-5h5cA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5h5c MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12
(Kluyveromyces
lactis) 		4 / 9 ILE A 221
ILE A 186
ILE A 188
LEU A 124
 None
 0.82A 5vkqB-5h5cA:
undetectable
5vkqC-5h5cA:
undetectable		 5vkqB-5h5cA:
9.65
5vkqC-5h5cA:
9.65