SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h5l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5h5l GLUTATHIONE
S-TRANSFERASE S2
(Nilaparvata
lugens) 		4 / 5 PRO A  17
ILE A 159
GLY A  13
TYR A   8
 None
None
PEG  A 302 (-3.5A)
GSH  A 301 ( 4.9A)
 1.12A 2jkjD-5h5lA:
undetectable		 2jkjD-5h5lA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5h5l GLUTATHIONE
S-TRANSFERASE S2
(Nilaparvata
lugens) 		4 / 5 PRO A  17
ILE A 159
GLY A  13
TYR A   8
 None
None
PEG  A 302 (-3.5A)
GSH  A 301 ( 4.9A)
 1.12A 2jkjF-5h5lA:
undetectable		 2jkjF-5h5lA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 5h5l GLUTATHIONE
S-TRANSFERASE S2
(Nilaparvata
lugens) 		4 / 5 PRO A  17
ILE A  18
PRO A  52
TYR A   8
 None
None
GSH  A 301 (-4.3A)
GSH  A 301 ( 4.9A)
 1.22A 3d9lA-5h5lA:
2.5
3d9lY-5h5lA:
undetectable		 3d9lA-5h5lA:
18.96
3d9lY-5h5lA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 5h5l GLUTATHIONE
S-TRANSFERASE S2
(Nilaparvata
lugens) 		5 / 12 PHE A  29
GLY A  15
ALA A  12
ARG A 197
ASP A  31
 None
 1.14A 4a6eA-5h5lA:
undetectable		 4a6eA-5h5lA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 5h5l GLUTATHIONE
S-TRANSFERASE S2
(Nilaparvata
lugens) 		4 / 6 ILE A  88
ASP A  89
ARG A  69
GLY A  72
 None
 0.65A 4oltA-5h5lA:
undetectable		 4oltA-5h5lA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 5h5l GLUTATHIONE
S-TRANSFERASE S2
(Nilaparvata
lugens) 		4 / 6 ILE A  88
ASP A  89
ARG A  69
GLY A  72
 None
 0.69A 4oltB-5h5lA:
0.9		 4oltB-5h5lA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 5h5l GLUTATHIONE
S-TRANSFERASE S2
(Nilaparvata
lugens) 		5 / 12 ASP A  31
ILE A  18
PRO A  17
ALA A  68
ILE A  67
 None
 1.16A 4uroC-5h5lA:
undetectable		 4uroC-5h5lA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 5h5l GLUTATHIONE
S-TRANSFERASE S2
(Nilaparvata
lugens) 		5 / 11 PHE A 133
ILE A  92
ILE A 154
ILE A 170
ILE A 171
 None
 1.05A 5hw8A-5h5lA:
undetectable
5hw8D-5h5lA:
undetectable		 5hw8A-5h5lA:
23.83
5hw8D-5h5lA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 5h5l GLUTATHIONE
S-TRANSFERASE S2
(Nilaparvata
lugens) 		4 / 8 ILE A  88
ASP A  89
ARG A  69
GLY A  72
 None
 0.70A 5hwaA-5h5lA:
undetectable		 5hwaA-5h5lA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 5h5l GLUTATHIONE
S-TRANSFERASE S2
(Nilaparvata
lugens) 		5 / 12 ASP A  31
PRO A  17
ARG A  19
GLY A  13
LEU A  14
 None
None
None
PEG  A 302 (-3.5A)
GSH  A 301 (-4.2A)
 1.24A 5m50B-5h5lA:
undetectable		 5m50B-5h5lA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 5h5l GLUTATHIONE
S-TRANSFERASE S2
(Nilaparvata
lugens) 		4 / 5 ARG A  69
ALA A  68
TYR A 155
GLN A  63
 None
None
None
GSH  A 301 (-3.1A)
 1.34A 6g9bA-5h5lA:
undetectable
6g9bB-5h5lA:
undetectable		 6g9bA-5h5lA:
18.50
6g9bB-5h5lA:
18.18