SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h5o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5h5o DIGUANYLATE CYCLASE
(Xanthomonas
campestris) 		4 / 8 ILE A  63
PHE A  36
VAL A 131
MET A 130
 None
 1.04A 1kb9A-5h5oA:
undetectable
1kb9C-5h5oA:
undetectable
1kb9D-5h5oA:
undetectable
1kb9E-5h5oA:
undetectable		 1kb9A-5h5oA:
15.13
1kb9C-5h5oA:
15.82
1kb9D-5h5oA:
22.94
1kb9E-5h5oA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 5h5o DIGUANYLATE CYCLASE
(Xanthomonas
campestris) 		5 / 11 HIS A 117
ALA A 116
MET A  61
GLY A  40
VAL A 131
 None
 1.32A 2uxpB-5h5oA:
undetectable		 2uxpB-5h5oA:
23.85