SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h5t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5h5t FLAGELLAR
HOOK-ASSOCIATED
PROTEIN 2
(Salmonella
enterica) 		5 / 10 THR A  86
ILE A 250
GLY A 249
GLY A  89
THR A  73
 None
 1.37A 2y7wB-5h5tA:
undetectable		 2y7wB-5h5tA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 5h5t FLAGELLAR
HOOK-ASSOCIATED
PROTEIN 2
(Salmonella
enterica) 		5 / 9 ALA A 208
ILE A 167
LEU A 183
ILE A 160
ILE A 144
 None
 0.84A 5nunA-5h5tA:
undetectable		 5nunA-5h5tA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CB4_A_BEZA501_0
(CANAVALIN)		 5h5t FLAGELLAR
HOOK-ASSOCIATED
PROTEIN 2
(Salmonella
enterica) 		4 / 8 LEU A 121
VAL A 197
LEU A 207
ILE A 131
 None
 0.87A 6cb4A-5h5tA:
undetectable		 6cb4A-5h5tA:
18.65