SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h5y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 5h5y NON-LEE ENCODED
EFFECTOR PROTEIN
NLEB
(Escherichia
coli) 		4 / 4 ILE A  85
MET A 219
VAL A  59
GLY A  86
 None
 1.04A 1e06B-5h5yA:
undetectable		 1e06B-5h5yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5h5y NON-LEE ENCODED
EFFECTOR PROTEIN
NLEB
(Escherichia
coli) 		5 / 12 ASP A  37
LEU A 264
LEU A 190
PRO A  41
GLY A 211
 None
 0.98A 1jffB-5h5yA:
undetectable		 1jffB-5h5yA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_2
(ANGIOTENSIN
CONVERTING ENZYME)		 5h5y NON-LEE ENCODED
EFFECTOR PROTEIN
NLEB
(Escherichia
coli) 		4 / 4 SER A 237
VAL A 240
PHE A 306
VAL A  24
 None
 1.46A 1o86A-5h5yA:
2.1		 1o86A-5h5yA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5h5y NON-LEE ENCODED
EFFECTOR PROTEIN
NLEB
(Escherichia
coli) 		5 / 12 ASP A  37
LEU A 264
LEU A 190
PRO A  41
GLY A 211
 None
 0.98A 2hxfB-5h5yA:
undetectable		 2hxfB-5h5yA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5h5y NON-LEE ENCODED
EFFECTOR PROTEIN
NLEB
(Escherichia
coli) 		5 / 12 ASP A  37
LEU A 264
LEU A 190
PRO A  41
GLY A 211
 None
 0.98A 2hxhB-5h5yA:
undetectable		 2hxhB-5h5yA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5h5y NON-LEE ENCODED
EFFECTOR PROTEIN
NLEB
(Escherichia
coli) 		5 / 12 ASP A  37
LEU A 264
LEU A 190
PRO A  41
GLY A 211
 None
 0.98A 2p4nB-5h5yA:
undetectable		 2p4nB-5h5yA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 5h5y NON-LEE ENCODED
EFFECTOR PROTEIN
NLEB
(Escherichia
coli) 		5 / 12 ASP A  37
LEU A 264
LEU A 190
PRO A  41
GLY A 211
 None
 0.98A 2wbeB-5h5yA:
undetectable		 2wbeB-5h5yA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 5h5y NON-LEE ENCODED
EFFECTOR PROTEIN
NLEB
(Escherichia
coli) 		5 / 12 ASP A  37
LEU A 264
LEU A 190
PRO A  41
GLY A 211
 None
 0.98A 3dcoB-5h5yA:
undetectable		 3dcoB-5h5yA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 5h5y NON-LEE ENCODED
EFFECTOR PROTEIN
NLEB
(Escherichia
coli) 		5 / 12 ASP A  37
LEU A 264
LEU A 190
PRO A  41
GLY A 211
 None
 0.98A 3edlB-5h5yA:
undetectable		 3edlB-5h5yA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_2
(PROTEASE)		 5h5y NON-LEE ENCODED
EFFECTOR PROTEIN
NLEB
(Escherichia
coli) 		5 / 10 GLY A 287
GLY A 267
LEU A 268
VAL A 256
ILE A 254
 None
 1.06A 3em4V-5h5yA:
undetectable		 3em4V-5h5yA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 5h5y NON-LEE ENCODED
EFFECTOR PROTEIN
NLEB
(Escherichia
coli) 		5 / 12 ASP A  37
LEU A 264
LEU A 190
PRO A  41
GLY A 211
 None
 0.96A 3iz0B-5h5yA:
undetectable		 3iz0B-5h5yA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_1
(ENDOTHIAPEPSIN)		 5h5y NON-LEE ENCODED
EFFECTOR PROTEIN
NLEB
(Escherichia
coli) 		5 / 12 GLY A 228
PHE A 309
ILE A 255
THR A  40
ILE A  36
 None
 1.09A 3pwwA-5h5yA:
undetectable		 3pwwA-5h5yA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 5h5y NON-LEE ENCODED
EFFECTOR PROTEIN
NLEB
(Escherichia
coli) 		3 / 3 ASP A  37
GLU A 212
GLY A 211
 None
 0.46A 3w9tA-5h5yA:
undetectable		 3w9tA-5h5yA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 5h5y NON-LEE ENCODED
EFFECTOR PROTEIN
NLEB
(Escherichia
coli) 		4 / 7 ILE A 314
HIS A 311
GLY A 225
LYS A 226
 None
 1.01A 4z69A-5h5yA:
2.4		 4z69A-5h5yA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5h5y NON-LEE ENCODED
EFFECTOR PROTEIN
NLEB
(Escherichia
coli) 		5 / 9 LEU A  43
ILE A 196
GLY A 194
GLY A 213
ALA A 189
 None
 0.94A 5o96A-5h5yA:
2.3
5o96B-5h5yA:
undetectable		 5o96A-5h5yA:
undetectable
5o96B-5h5yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_D_SAMD501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5h5y NON-LEE ENCODED
EFFECTOR PROTEIN
NLEB
(Escherichia
coli) 		5 / 10 LEU A  43
ILE A 196
GLY A 194
GLY A 213
ALA A 189
 None
 0.79A 5o96C-5h5yA:
2.3
5o96D-5h5yA:
undetectable		 5o96C-5h5yA:
undetectable
5o96D-5h5yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5h5y NON-LEE ENCODED
EFFECTOR PROTEIN
NLEB
(Escherichia
coli) 		5 / 12 LEU A 284
ARG A 186
ILE A 254
ILE A 249
LEU A 227
 None
 0.78A 5ycnA-5h5yA:
undetectable		 5ycnA-5h5yA:
undetectable